Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q02818

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
26	unknown peptidase	1-461	P		NT	<%Agarwal et al., 2012[]%>
53	trypsin 1	27-461	N		MS	Schilling & Overall, 2008
56	meprin beta subunit	27-461	N		MS	Becker-Pauly et al., 2011
69	trypsin 1	27-461	N		MS	Schilling & Overall, 2008
167	meprin alpha subunit	27-461	N		MS	Becker-Pauly et al., 2011
167	meprin beta subunit	27-461	N		MS	Becker-Pauly et al., 2011
220	meprin alpha subunit	27-461	N		MS	Becker-Pauly et al., 2011
223	meprin alpha subunit	27-461	N		MS	Becker-Pauly et al., 2011
223	meprin beta subunit	27-461	N		MS	Becker-Pauly et al., 2011
226	meprin alpha subunit	27-461	N		MS	Becker-Pauly et al., 2011
226	meprin beta subunit	27-461	N		MS	Becker-Pauly et al., 2011
327	meprin beta subunit	27-461	N		MS	Becker-Pauly et al., 2011
357	meprin beta subunit	27-461	N		MS	Becker-Pauly et al., 2011