Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q02539

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-215	P		NT	<%Agarwal et al., 2012[]%>
64	matrix metallopeptidase-2	63-74	N		MS	Schilling & Overall, 2008
66	trypsin 1	2-215	N		MS	Schilling & Overall, 2008
67	trypsin 1	2-215	N		MS	Schilling & Overall, 2008
69	cathepsin G	67-78	N		MS	Schilling & Overall, 2008
70	granzyme A	1-215	N			Van Damme et al., 2010
74	chymotrypsin A (cattle-type)	2-215	N		MS	Schilling & Overall, 2008
77	peptidyl-Lys metallopeptidase	1-215	N		MS
78	trypsin 1	2-215	N		MS	Schilling & Overall, 2008
89	matrix metallopeptidase-2	87-108	N		MS	Schilling & Overall, 2008
108	chymotrypsin A (cattle-type)	2-215	N		MS	Schilling & Overall, 2008