Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P62633

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-177	P	release of an initiating methionine	MS	Van Damme P et al., 2005
45	meprin beta subunit	42-56	N		MS	Becker-Pauly et al., 2011
99	astacin	96-109	N		MS	Becker-Pauly et al., 2011
118	lysyl endopeptidase (bacteria)	1-177	N		MS
130	lysyl endopeptidase (bacteria)	1-177	N		MS
139	trypsin 1	1-177	N		MS	Schilling & Overall, 2008
152	trypsin 1	1-177	N		MS	Schilling & Overall, 2008