Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P62269

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-152	P		NT	<%Agarwal et al., 2012[]%>
14	trypsin 1	2-152	N		MS	Schilling & Overall, 2008
23	trypsin 1	2-152	N		MS	Schilling & Overall, 2008
46	granzyme A	1-152	N			Van Damme et al., 2010
55	granzyme A	1-152	N			Van Damme et al., 2010
55	trypsin 1	2-152	N		MS	Schilling & Overall, 2008
66	trypsin 1	2-152	N		MS	Schilling & Overall, 2008
75	trypsin 1	2-152	N		MS	Schilling & Overall, 2008
77	meprin beta subunit	2-152	N		MS	Becker-Pauly et al., 2011
78	trypsin 1	2-152	N		MS	Schilling & Overall, 2008
86	trypsin 1	2-152	N		MS	Schilling & Overall, 2008
93	peptidyl-Lys metallopeptidase	1-152	N		MS
94	trypsin 1	2-152	N		MS	Schilling & Overall, 2008
105	peptidyl-Lys metallopeptidase	1-152	N		MS
106	trypsin 1	2-152	N		MS	Schilling & Overall, 2008
114	peptidyl-Lys metallopeptidase	1-152	N		MS