Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P60660

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-151	P		NT	<%Agarwal et al., 2012[]%>
10	meprin beta subunit	2-151	N		MS	Becker-Pauly et al., 2011
13	trypsin 1	2-151	N		MS	Schilling & Overall, 2008
21	trypsin 1	2-151	N		MS	Schilling & Overall, 2008
37	trypsin 1	2-151	N		MS	Schilling & Overall, 2008
50	trypsin 1	2-151	N		MS	Schilling & Overall, 2008
67	meprin beta subunit	64-79	N		MS	Becker-Pauly et al., 2011
79	trypsin 1	2-151	N		MS	Schilling & Overall, 2008
81	trypsin 1	2-151	N		MS	Schilling & Overall, 2008
94	trypsin 1	2-151	N		MS	Schilling & Overall, 2008
110	trypsin 1	2-151	N		MS	Schilling & Overall, 2008
119	trypsin 1	2-151	N		MS	Schilling & Overall, 2008