Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P58772

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
12	calpain-2	1-284	P			Goll et al., 2003
27	calpain-2	1-284	P			Goll et al., 2003
183	calpain-2	1-284	P			Goll et al., 2003
204	calpain-2	1-284	P			Goll et al., 2003
205	calpain-2	1-284	P			Goll et al., 2003
208	calpain-2	1-284	P			Goll et al., 2003
212	calpain-2	1-284	P			Goll et al., 2003
219	calpain-2	1-284	P	normal turnover		Goll et al., 2003
223	calpain-2	1-284	P			Goll et al., 2003
241	calpain-2	1-284	P			Goll et al., 2003
256	calpain-2	1-284	P			Goll et al., 2003