Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P48739

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-271	P		NT	<%Agarwal et al., 2012[]%>
33	meprin alpha subunit	30-44	N		MS	Becker-Pauly et al., 2011
73	trypsin 1	2-271	N		MS	Schilling & Overall, 2008
86	trypsin 1	2-271	N		MS	Schilling & Overall, 2008
104	trypsin 1	2-271	N		MS	Schilling & Overall, 2008
110	trypsin 1	2-271	N		MS	Schilling & Overall, 2008
134	trypsin 1	2-271	N		MS	Schilling & Overall, 2008
146	trypsin 1	2-271	N		MS	Schilling & Overall, 2008
155	trypsin 1	2-271	N		MS	Schilling & Overall, 2008
167	trypsin 1	2-271	N		MS	Schilling & Overall, 2008