Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P40429

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-203	P		NT	<%Agarwal et al., 2012[]%>
105	meprin beta subunit	102-115	N		MS	Becker-Pauly et al., 2011
106	astacin	103-115	N		MS	Becker-Pauly et al., 2011
117	trypsin 1	2-203	N		MS	Schilling & Overall, 2008
125	trypsin 1	2-203	N		MS	Schilling & Overall, 2008
133	peptidyl-Lys metallopeptidase	1-203	N		MS
140	trypsin 1	2-203	N		MS	Schilling & Overall, 2008
147	peptidyl-Lys metallopeptidase	1-203	N		MS
148	granzyme A	1-203	N			Van Damme et al., 2010
148	trypsin 1	2-203	N		MS	Schilling & Overall, 2008