Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P39019

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-145	P		NT	<%Agarwal et al., 2012[]%>
43	trypsin 1	2-145	N		MS	Schilling & Overall, 2008
56	trypsin 1	2-145	N		MS	Schilling & Overall, 2008
102	granzyme A	1-145	N			Van Damme et al., 2010
102	trypsin 1	2-145	N		MS	Schilling & Overall, 2008
105	meprin alpha subunit	2-145	N		MS	Becker-Pauly et al., 2011
106	meprin alpha subunit	2-145	N		MS	Becker-Pauly et al., 2011
111	trypsin 1	2-145	N		MS	Schilling & Overall, 2008
121	peptidyl-Lys metallopeptidase	1-145	N		MS
133	trypsin 1	2-145	N		MS	Schilling & Overall, 2008
143	trypsin 1	2-145	N		MS	Schilling & Overall, 2008