Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P37889

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
26	unknown peptidase	1-1174	P	release of a signal peptide	NT	Pan et al., 1993
235	matrix metallopeptidase-3	27-1221	P	normal turnover		Nagase, 2004
259	matrix metallopeptidase-3	27-1221	P	normal turnover		Nagase, 2004
569	matrix metallopeptidase-3	27-1221	P	normal turnover		Nagase, 2004