Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P30885

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
19	unknown peptidase	1-401	P		NT	<%Agarwal et al., 2012[]%>
252	furin	20-401	P		MU	Nelson & Christian, 2009
252	PCSK5 peptidase	20-401	P		MU	Nelson & Christian, 2009
287	furin	20-401	P	release of an activation peptide	MU	Nelson & Christian, 2009
287	PCSK5 peptidase	20-401	P	release of an activation peptide	MU	Nelson & Christian, 2009