Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P29476

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site Peptidase Residue range Cleavage type Description Evidence Reference
188 trypsin 1 1-1429 N Lowe et al., 1996
220 trypsin 1 1-1429 N Lowe et al., 1996
270 chymotrypsin A (cattle-type) 1-1429 N Lowe et al., 1996
274 chymotrypsin A (cattle-type) 1-1429 N Lowe et al., 1996
343 trypsin 1 1-1429 N Lowe et al., 1996
349 trypsin 1 1-1429 N Lowe et al., 1996
727 trypsin 1 1-1429 N Lowe et al., 1996
743 trypsin 1 1-1429 N Lowe et al., 1996
844 trypsin 1 1-1429 N Lowe et al., 1996
851 chymotrypsin A (cattle-type) 1-1429 N Lowe et al., 1996
855 trypsin 1 1-1429 N Lowe et al., 1996
952 trypsin 1 1-1429 N Lowe et al., 1996
1409 trypsin 1 1-1429 N Lowe et al., 1996