Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P26583

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-209	P		NT	<%Agarwal et al., 2012[]%>
11	peptidyl-Lys metallopeptidase	1-209	N		MS
27	peptidyl-Lys metallopeptidase	1-209	N		MS
65	granzyme A	8-208	P			Fan et al., 2002
114	trypsin 1	2-209	N		MS	Schilling & Overall, 2008
127	trypsin 1	2-209	N		MS	Schilling & Overall, 2008
128	trypsin 1	2-209	N		MS	Schilling & Overall, 2008
139	trypsin 1	2-209	N		MS	Schilling & Overall, 2008
141	lysyl endopeptidase (bacteria)	1-209	N		MS