Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P20029

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
19	unknown peptidase	1-655	P	release of a signal peptide	NT	Merrick et al., 1994
38	matrix metallopeptidase-2	20-655	N		MS	auf dem Keller et al., 2010
50	matrix metallopeptidase-2	20-655	N		MS	auf dem Keller et al., 2010
52	matrix metallopeptidase-2	20-655	N		MS	auf dem Keller et al., 2010
66	cathepsin E	20-655	P		MS	Impens et al., 2010
66	matrix metallopeptidase-2	20-655	N		MS	auf dem Keller et al., 2010
75	matrix metallopeptidase-2	20-655	N		MS	auf dem Keller et al., 2010
84	matrix metallopeptidase-2	20-655	N		MS	auf dem Keller et al., 2010
207	matrix metallopeptidase-2	20-655	N		MS	auf dem Keller et al., 2010
267	cathepsin E	20-655	P		MS	Impens et al., 2010
312	matrix metallopeptidase-2	20-655	N		MS	auf dem Keller et al., 2010
313	cathepsin E	20-655	P		MS	Impens et al., 2010
330	matrix metallopeptidase-2	20-655	N		MS	auf dem Keller et al., 2010
417	cytotoxin SubAB	20-655	P			Paton et al., 2006
549	cathepsin E	20-655	P		MS	Impens et al., 2010