Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P18827

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
22	unknown peptidase	1-310	P		NT	<%Agarwal et al., 2012[]%>
82	membrane-type matrix metallopeptidase-1	23-310	P			Li et al., 2004
96	meprin beta subunit	23-310	N		MS	Becker-Pauly et al., 2011
213	meprin beta subunit	23-310	N		MS	Becker-Pauly et al., 2011
214	meprin beta subunit	23-310	N		MS	Becker-Pauly et al., 2011
216	meprin beta subunit	23-310	N		MS	Becker-Pauly et al., 2011
242	unknown peptidase	1-310	P		NT	<%Agarwal et al., 2012[]%>
245	membrane-type matrix metallopeptidase-1	23-310	P			Endo et al., 2003