Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P13727

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
16	unknown peptidase	1-222	P	release of a signal peptide	NT	Shikata et al., 1993
33	thermolysin	17-222	N			Glerup et al., 2005
53	thermolysin	17-222	N			Glerup et al., 2005
86	thermolysin	17-222	N			Glerup et al., 2005
95	thermolysin	17-222	N			Glerup et al., 2005
97	thermolysin	17-222	N			Glerup et al., 2005
105	unknown peptidase	1-222	P		NT	<%Agarwal et al., 2012[]%>
109	thermolysin	17-222	N			Glerup et al., 2005
122	thermolysin	17-222	N			Glerup et al., 2005
128	thermolysin	17-222	N			Glerup et al., 2005
142	thermolysin	17-222	N			Glerup et al., 2005
162	thermolysin	17-222	N			Glerup et al., 2005
171	thermolysin	17-222	N			Glerup et al., 2005
190	thermolysin	17-222	N			Glerup et al., 2005
193	thermolysin	17-222	N			Glerup et al., 2005
209	thermolysin	17-222	N			Glerup et al., 2005
212	thermolysin	17-222	N			Glerup et al., 2005
215	thermolysin	17-222	N			Glerup et al., 2005