Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P09237

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
17	unknown peptidase	1-267	P	release of a signal peptide	NT	Miyazaki et al., 1990
22	meprin alpha subunit	95-267	N		MS	Becker-Pauly et al., 2011
22	meprin beta subunit	18-267	N		MS	Becker-Pauly et al., 2011
23	meprin alpha subunit	18-94	N		MS	Becker-Pauly et al., 2011
23	meprin beta subunit	18-267	N		MS	Becker-Pauly et al., 2011
29	meprin beta subunit	18-267	N		MS	Becker-Pauly et al., 2011
32	meprin alpha subunit	95-267	N		MS	Becker-Pauly et al., 2011
32	meprin beta subunit	18-267	N		MS	Becker-Pauly et al., 2011
86	trypsin 1	18-267	N			Crabbe et al., 1992
94	matrix metallopeptidase-3	18-267	P	release of an activation peptide		Nagase, 2004
94	matrix metallopeptidase-7	18-267	P	release of an activation peptide		Woessner, 2004
178	meprin alpha subunit	95-267	N		MS	Becker-Pauly et al., 2011
180	meprin alpha subunit	18-94	N		MS	Becker-Pauly et al., 2011
180	meprin beta subunit	95-267	N		MS	Becker-Pauly et al., 2011
183	meprin alpha subunit	95-267	N		MS	Becker-Pauly et al., 2011
183	meprin beta subunit	95-267	N		MS	Becker-Pauly et al., 2011
188	meprin alpha subunit	18-94	N		MS	Becker-Pauly et al., 2011
188	meprin beta subunit	95-267	N		MS	Becker-Pauly et al., 2011