Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P07602

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
16	unknown peptidase	1-527	P	release of a signal peptide	NT	Kondoh et al., 1991
58	unknown peptidase	1-524	P		NT	<%Agarwal et al., 2012[]%>
59	unknown peptidase	1-524	P		NT	<%Agarwal et al., 2012[]%>
67	trypsin 1	60-142	N		MS	Schilling & Overall, 2008
107	trypsin 1	60-142	N		MS	Schilling & Overall, 2008
122	trypsin 1	60-142	N		MS	Schilling & Overall, 2008
142	unknown peptidase	1-524	P		NT	<%Agarwal et al., 2012[]%>
194	unknown peptidase	1-524	P		NT	<%Agarwal et al., 2012[]%>
273	unknown peptidase	1-524	P		NT	<%Agarwal et al., 2012[]%>
274	unknown peptidase	1-524	P		NT	<%Agarwal et al., 2012[]%>
309	unknown peptidase	1-524	P		NT	<%Agarwal et al., 2012[]%>
310	unknown peptidase	1-524	P		NT	<%Agarwal et al., 2012[]%>
391	unknown peptidase	1-524	P		NT	<%Agarwal et al., 2012[]%>
403	unknown peptidase	1-524	P		NT	<%Agarwal et al., 2012[]%>
404	unknown peptidase	1-524	P		NT	<%Agarwal et al., 2012[]%>
405	unknown peptidase	1-524	P		MS	Van Damme et al., 2005
486	unknown peptidase	1-524	P		NT	<%Agarwal et al., 2012[]%>
487	unknown peptidase	1-524	P		NT	<%Agarwal et al., 2012[]%>