Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P04405

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
18	signalase (animal) 21 kDa component	1-485	P	release of a signal peptide	NT	Staswick et al., 1984
296	unknown peptidase	1-485	P		NT	<%Agarwal et al., 2012[]%>
300	unknown peptidase	1-485	P		NT	<%Agarwal et al., 2012[]%>
480	unknown peptidase	1-485	P		NT	<%Agarwal et al., 2012[]%>