Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P02649

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
18	unknown peptidase	1-317	P	release of a signal peptide	NT	Rall et al., 1982
85	membrane-type matrix metallopeptidase-1	19-317	P			Aoki et al., 2005
93	membrane-type matrix metallopeptidase-1	19-317	P			Aoki et al., 2005
194	membrane-type matrix metallopeptidase-1	19-317	P			Park et al., 2008
201	membrane-type matrix metallopeptidase-1	19-317	P			Park et al., 2008
220	membrane-type matrix metallopeptidase-1	19-317	P			Park et al., 2008
246	membrane-type matrix metallopeptidase-1	19-317	P			Aoki et al., 2005
255	membrane-type matrix metallopeptidase-1	19-317	P			Aoki et al., 2005
267	membrane-type matrix metallopeptidase-1	19-317	P			Park et al., 2008
296	membrane-type matrix metallopeptidase-1	19-317	P			Aoki et al., 2005