Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P02545

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-664	P	release of an initiating methionine	MS
30	meprin alpha subunit	1-646	N		MS	Becker-Pauly et al., 2011
30	meprin beta subunit	1-646	N		MS	Becker-Pauly et al., 2011
230	caspase-6	1-664	P			Lee et al., 2006
252	meprin alpha subunit	1-661	N		MS	Becker-Pauly et al., 2011
252	meprin beta subunit	1-646	N		MS	Becker-Pauly et al., 2011
253	meprin alpha subunit	1-661	N		MS	Becker-Pauly et al., 2011
253	meprin beta subunit	1-664	N		MS	Becker-Pauly et al., 2011
646	farnesylated-protein converting enzyme 1	1-664	P		MU	Corrigan et al., 2005
661	unknown peptidase	1-664	P		NT	<%Agarwal et al., 2012[]%>