Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P01012

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-386	P		NT	<%Agarwal et al., 2012[]%>
25	legumain, animal-type	20-28	N		NT	Dando et al., 1999
27	unknown peptidase	1-386	P	release of a signal peptide	NT	Thompson & Fisher, 1978
48	unknown peptidase	1-386	P		NT	<%Agarwal et al., 2012[]%>
55	legumain, animal-type	53-62	N		NT	Dando et al., 1999
95	legumain, animal-type	93-102	N		NT	Dando et al., 1999
155	legumain, animal-type	149-162	N		NT	Dando et al., 1999
160	legumain, animal-type	149-162	N		NT	Dando et al., 1999
177	legumain, animal-type	173-183	N		NT	Dando et al., 1999
226	peptidyl-Lys metallopeptidase	1-386	N		MS
261	legumain, animal-type	258-265	N		NT	Dando et al., 1999
263	peptidyl-Lys metallopeptidase	1-386	N		MS
353	unknown peptidase	1-386	P		NT	<%Agarwal et al., 2012[]%>
359	unknown peptidase	1-386	P		NT	<%Agarwal et al., 2012[]%>
375	legumain, animal-type	368-378	N		NT	Dando et al., 1999