Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00720

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
18	pepsin A	16-24	N		NT	Amagase et al., 1969
18	nepenthesin	16-24	N		NT	Amagase et al., 1969
20	nepenthesin	16-24	N		NT	Amagase et al., 1969
66	pepsin A	66-76	N		NT	Amagase et al., 1969
67	pepsin A	66-76	N		NT	Amagase et al., 1969
72	nepenthesin	66-76	N		NT	Amagase et al., 1969
84	pepsin A	84-96	N		NT	Amagase et al., 1969
88	pepsin A	84-96	N		NT	Amagase et al., 1969
88	nepenthesin	84-96	N		NT	Amagase et al., 1969
91	pepsin A	84-96	N		NT	Amagase et al., 1969
91	nepenthesin	84-96	N		NT	Amagase et al., 1969
126	pepsin A	126-135	N		NT	Amagase et al., 1969
129	pepsin A	126-135	N		NT	Amagase et al., 1969
129	nepenthesin	126-135	N		NT	Amagase et al., 1969
130	pepsin A	126-135	N		NT	Amagase et al., 1969
132	pepsin A	126-135	N		NT	Amagase et al., 1969
133	pepsin A	126-135	N		NT	Amagase et al., 1969
158	pepsin A	155-162	N		NT	Amagase et al., 1969
160	pepsin A	155-162	N		NT	Amagase et al., 1969
160	nepenthesin	155-162	N		NT	Amagase et al., 1969