Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00508

,

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
22	unknown peptidase	1-423	P		NT	<%Agarwal et al., 2012[]%>
44	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
46	trypsin 1	1-423	N			Graf-Hausner et al., 1983
60	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
61	trypsin 1	1-423	N			Graf-Hausner et al., 1983
68	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
83	trypsin 1	1-423	N			Graf-Hausner et al., 1983
84	trypsin 1	1-423	N			Graf-Hausner et al., 1983
87	trypsin 1	1-423	N			Graf-Hausner et al., 1983
100	trypsin 1	1-423	N			Graf-Hausner et al., 1983
118	trypsin 1	1-423	N			Graf-Hausner et al., 1983
132	trypsin 1	1-423	N			Graf-Hausner et al., 1983
140	trypsin 1	1-423	N			Graf-Hausner et al., 1983
146	trypsin 1	1-423	N			Graf-Hausner et al., 1983
163	trypsin 1	1-423	N			Graf-Hausner et al., 1983
173	trypsin 1	1-423	N			Graf-Hausner et al., 1983
178	trypsin 1	1-423	N			Graf-Hausner et al., 1983
193	trypsin 1	1-423	N			Graf-Hausner et al., 1983
197	trypsin 1	1-423	N			Graf-Hausner et al., 1983
201	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
203	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
207	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
215	trypsin 1	1-423	N			Graf-Hausner et al., 1983
219	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
229	trypsin 1	1-423	N			Graf-Hausner et al., 1983
232	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
249	trypsin 1	1-423	N			Graf-Hausner et al., 1983
255	trypsin 1	1-423	N			Graf-Hausner et al., 1983
266	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
270	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
277	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
280	trypsin 1	1-423	N			Graf-Hausner et al., 1983
281	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
284	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
289	trypsin 1	1-423	N			Graf-Hausner et al., 1983
296	trypsin 1	1-423	N			Graf-Hausner et al., 1983
301	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
304	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
318	trypsin 1	1-423	N			Graf-Hausner et al., 1983
330	trypsin 1	1-423	N			Graf-Hausner et al., 1983
333	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
343	trypsin 1	1-423	N			Graf-Hausner et al., 1983
348	trypsin 1	1-423	N			Graf-Hausner et al., 1983
351	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
355	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
362	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
376	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
386	trypsin 1	1-423	N			Graf-Hausner et al., 1983
387	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
391	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
394	chymotrypsin A (cattle-type)	1-423	N			Graf-Hausner et al., 1983
400	trypsin 1	1-423	N			Graf-Hausner et al., 1983