Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00434

,

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
5	thermolysin	1-296	N			Mazza et al., 1980
7	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
14	thermolysin	1-296	N			Mazza et al., 1980
15	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
17	thermolysin	1-296	N			Mazza et al., 1980
19	trypsin 1	1-296	N			Mazza et al., 1980
23	trypsin 1	1-296	N			Mazza et al., 1980
24	thermolysin	1-296	N			Mazza et al., 1980
29	thermolysin	1-296	N			Mazza et al., 1980
31	trypsin 1	1-296	N			Mazza et al., 1980
37	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
38	trypsin 1	1-296	N			Mazza et al., 1980
40	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
61	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
71	trypsin 1	1-296	N			Mazza et al., 1980
72	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
75	trypsin 1	1-296	N			Mazza et al., 1980
77	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
84	trypsin 1	1-296	N			Mazza et al., 1980
89	trypsin 1	1-296	N			Mazza et al., 1980
101	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
106	trypsin 1	1-296	N			Mazza et al., 1980
112	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
117	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
120	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
120	trypsin 1	1-296	N			Mazza et al., 1980
123	trypsin 1	1-296	N			Mazza et al., 1980
124	trypsin 1	1-296	N			Mazza et al., 1980
127	trypsin 1	1-296	N			Mazza et al., 1980
152	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
157	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
160	trypsin 1	1-296	N			Mazza et al., 1980
162	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
164	thermolysin	1-296	N			Mazza et al., 1980
165	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
169	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
170	thermolysin	1-296	N			Mazza et al., 1980
175	trypsin 1	1-296	N			Mazza et al., 1980
178	thermolysin	1-296	N			Mazza et al., 1980
179	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
180	trypsin 1	1-296	N			Mazza et al., 1980
182	trypsin 1	1-296	N			Mazza et al., 1980
184	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
192	thermolysin	1-296	N			Mazza et al., 1980
193	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
195	thermolysin	1-296	N			Mazza et al., 1980
196	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
197	trypsin 1	1-296	N			Mazza et al., 1980
199	trypsin 1	1-296	N			Mazza et al., 1980
203	trypsin 1	1-296	N			Mazza et al., 1980
211	thermolysin	1-296	N			Mazza et al., 1980
214	thermolysin	1-296	N			Mazza et al., 1980
215	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
223	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
228	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
229	trypsin 1	1-296	N			Mazza et al., 1980
235	trypsin 1	1-296	N			Mazza et al., 1980
237	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
238	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
245	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
255	trypsin 1	1-296	N			Mazza et al., 1980
257	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
264	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
268	chymotrypsin A (cattle-type)	1-296	N			Mazza et al., 1980
274	trypsin 1	1-296	N			Mazza et al., 1980
289	trypsin 1	1-296	N			Mazza et al., 1980
294	trypsin 1	1-296	N			Mazza et al., 1980