Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00325

,

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-375	P		NT	<%Agarwal et al., 2012[]%>
6	trypsin 1	1-375	N			Hempel et al., 1984
9	trypsin 1	1-375	N			Hempel et al., 1984
11	trypsin 1	1-375	N			Hempel et al., 1984
19	trypsin 1	1-375	N			Hempel et al., 1984
33	trypsin 1	1-375	N			Hempel et al., 1984
38	trypsin 1	1-375	N			Hempel et al., 1984
40	trypsin 1	1-375	N			Hempel et al., 1984
48	trypsin 1	1-375	N			Hempel et al., 1984
89	trypsin 1	1-375	N			Hempel et al., 1984
100	trypsin 1	1-375	N			Hempel et al., 1984
105	trypsin 1	1-375	N			Hempel et al., 1984
114	trypsin 1	1-375	N			Hempel et al., 1984
121	trypsin 1	1-375	N			Hempel et al., 1984
130	trypsin 1	1-375	N			Hempel et al., 1984
134	trypsin 1	1-375	N			Hempel et al., 1984
160	trypsin 1	1-375	N			Hempel et al., 1984
169	trypsin 1	1-375	N			Hempel et al., 1984
189	trypsin 1	1-375	N			Hempel et al., 1984
213	trypsin 1	1-375	N			Hempel et al., 1984
219	trypsin 1	1-375	N			Hempel et al., 1984
229	trypsin 1	1-375	N			Hempel et al., 1984
232	trypsin 1	1-375	N			Hempel et al., 1984
234	trypsin 1	1-375	N			Hempel et al., 1984
248	trypsin 1	1-375	N			Hempel et al., 1984
256	trypsin 1	1-375	N			Hempel et al., 1984
272	trypsin 1	1-375	N			Hempel et al., 1984
313	trypsin 1	1-375	N			Hempel et al., 1984
316	trypsin 1	1-375	N			Hempel et al., 1984
324	trypsin 1	1-375	N			Hempel et al., 1984
326	trypsin 1	1-375	N			Hempel et al., 1984
331	trypsin 1	1-375	N			Hempel et al., 1984
339	trypsin 1	1-375	N			Hempel et al., 1984
367	trypsin 1	1-375	N			Hempel et al., 1984
370	trypsin 1	1-375	N			Hempel et al., 1984