Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00222

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site Peptidase Residue range Cleavage type Description Evidence Reference
2 thermolysin 1-97 N Rao et al., 1970
3 chymotrypsin A (cattle-type) 1-97 N Rao et al., 1970
4 thermolysin 1-97 N Rao et al., 1970
6 thermolysin 1-97 N Rao et al., 1970
7 thermolysin 1-97 N Rao et al., 1970
7 chymotrypsin A (cattle-type) 1-97 N Rao et al., 1970
23 thermolysin 1-97 N Rao et al., 1970
23 chymotrypsin A (cattle-type) 1-97 N Rao et al., 1970
30 thermolysin 1-97 N Rao et al., 1970
32 thermolysin 1-97 N Rao et al., 1970
36 thermolysin 1-97 N Rao et al., 1970
37 chymotrypsin A (cattle-type) 1-97 N Rao et al., 1970
50 thermolysin 1-97 N Rao et al., 1970
52 thermolysin 1-97 N Rao et al., 1970
55 thermolysin 1-97 N Rao et al., 1970
63 thermolysin 1-97 N Rao et al., 1970
68 thermolysin 1-97 N Rao et al., 1970
73 thermolysin 1-97 N Rao et al., 1970
73 chymotrypsin A (cattle-type) 1-97 N Rao et al., 1970
77 thermolysin 1-97 N Rao et al., 1970
81 thermolysin 1-97 N Rao et al., 1970
86 thermolysin 1-97 N Rao et al., 1970
94 thermolysin 1-97 N Rao et al., 1970