Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00049

,

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
2	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
14	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
17	trypsin 1	1-107	N			Bitar et al., 1972
30	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
31	trypsin 1	1-107	N			Bitar et al., 1972
35	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
37	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
40	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
42	trypsin 1	1-107	N			Bitar et al., 1972
50	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
52	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
63	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
69	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
71	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
72	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
76	trypsin 1	1-107	N			Bitar et al., 1972
77	trypsin 1	1-107	N			Bitar et al., 1972
78	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
83	trypsin 1	1-107	N			Bitar et al., 1972
84	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
86	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
89	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
90	trypsin 1	1-107	N			Bitar et al., 1972
91	trypsin 1	1-107	N			Bitar et al., 1972
93	trypsin 1	1-107	N			Bitar et al., 1972
95	trypsin 1	1-107	N			Bitar et al., 1972
101	chymotrypsin A (cattle-type)	1-107	N			Bitar et al., 1972
103	trypsin 1	1-107	N			Bitar et al., 1972