Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00042

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
4	chymotrypsin A (cattle-type)	1-109	N			Becam et al., 1981
5	trypsin 1	1-109	N			Becam et al., 1981
10	trypsin 1	1-109	N			Becam et al., 1981
16	chymotrypsin A (cattle-type)	1-109	N			Becam et al., 1981
17	trypsin 1	1-109	N			Becam et al., 1981
19	trypsin 1	1-109	N			Becam et al., 1981
28	trypsin 1	1-109	N			Becam et al., 1981
33	trypsin 1	1-109	N			Becam et al., 1981
44	trypsin 1	1-109	N			Becam et al., 1981
48	trypsin 1	1-109	N			Becam et al., 1981
52	chymotrypsin A (cattle-type)	1-109	N			Becam et al., 1981
54	chymotrypsin A (cattle-type)	1-109	N			Becam et al., 1981
60	trypsin 1	1-109	N			Becam et al., 1981
70	chymotrypsin A (cattle-type)	1-109	N			Becam et al., 1981
80	chymotrypsin A (cattle-type)	1-109	N			Becam et al., 1981
85	trypsin 1	1-109	N			Becam et al., 1981
86	chymotrypsin A (cattle-type)	1-109	N			Becam et al., 1981
91	chymotrypsin A (cattle-type)	1-109	N			Becam et al., 1981
92	trypsin 1	1-109	N			Becam et al., 1981
93	trypsin 1	1-109	N			Becam et al., 1981
97	trypsin 1	1-109	N			Becam et al., 1981
103	chymotrypsin A (cattle-type)	1-109	N			Becam et al., 1981