Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00032

,

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
5	trypsin 1	1-104	N			Brown et al., 1972
8	trypsin 1	1-104	N			Brown et al., 1972
10	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
13	trypsin 1	1-104	N			Brown et al., 1972
25	trypsin 1	1-104	N			Brown et al., 1972
26	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
27	trypsin 1	1-104	N			Brown et al., 1972
32	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
36	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
38	trypsin 1	1-104	N			Brown et al., 1972
39	trypsin 1	1-104	N			Brown et al., 1972
46	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
48	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
53	trypsin 1	1-104	N			Brown et al., 1972
55	trypsin 1	1-104	N			Brown et al., 1972
59	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
60	trypsin 1	1-104	N			Brown et al., 1972
65	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
67	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
68	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
72	trypsin 1	1-104	N			Brown et al., 1972
73	trypsin 1	1-104	N			Brown et al., 1972
74	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
79	trypsin 1	1-104	N			Brown et al., 1972
80	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
82	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
85	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
86	trypsin 1	1-104	N			Brown et al., 1972
91	trypsin 1	1-104	N			Brown et al., 1972
94	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
97	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972
98	chymotrypsin A (cattle-type)	1-104	N			Brown et al., 1972