Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence O94985

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
28	unknown peptidase	1-971	P	release of a signal peptide	NT	Araki et al., 2004
55	meprin alpha subunit	29-981	N		MS	Becker-Pauly et al., 2011
55	meprin beta subunit	29-981	N		MS	Becker-Pauly et al., 2011
96	meprin alpha subunit	29-981	N		MS	Becker-Pauly et al., 2011
96	meprin beta subunit	29-981	N		MS	Becker-Pauly et al., 2011
825	unknown peptidase	1-981	P		NT	<%Agarwal et al., 2012[]%>