Literature for peptidase C01.036: cathepsin K

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

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    2025
  1. Brizuela,L., Buchet,R., Bougault,C. and Mebarek,S.
    Cathepsin K Inhibitors as Potential Drugs for the Treatment of Osteoarthritis
    Int J Mol Sci26, PubMed  Europe PubMed DOI  V
  2. 2024
  3. Janin,Y.L.
    On the origins of SARS-CoV-2 main protease inhibitors
    RSC Med Chem15, 81-118. PubMed  Europe PubMed DOI  V  I
  4. Moon,D.O.
    Review of Cathepsin K Inhibitor Development and the Potential Role of Phytochemicals
    Molecules30, PubMed  Europe PubMed DOI  V
  5. 2022
  6. Mijanovic,O., Jakovleva,A., Brankovic,A., Zdravkova,K., Pualic,M., Belozerskaya,T.A., Nikitkina,A.I., Parodi,A. and Zamyatnin,A.A., Jr.
    Cathepsin K in Pathological Conditions and New Therapeutic and Diagnostic Perspectives
    Int J Mol Sci23, PubMed  Europe PubMed DOI  V
  7. Qian,D., He,L., Zhang,Q., Li,W., Tang,D., Wu,C., Yang,F., Li,K. and Zhang,H.
    Cathepsin K: A Versatile Potential Biomarker and Therapeutic Target for Various Cancers
    Curr Oncol29, 5963-5987. PubMed  Europe PubMed DOI  V
  8. Zou,N., Liu,R. and Li,C.
    Cathepsin K(+) Non-Osteoclast Cells in the Skeletal System: Function, Models, Identity, and Therapeutic Implications
    Front Cell Dev Biol10, 818462-818462. PubMed  Europe PubMed DOI  V
  9. 2021
  10. Calio,A., Brunelli,M., Gobbo,S., Argani,P., Munari,E., Netto,G. and Martignoni,G.
    Cathepsin K: A Novel Diagnostic and Predictive Biomarker for Renal Tumors
    Cancers (Basel)13, PubMed  Europe PubMed DOI  V
  11. 2020
  12. Kensara,A., Hefni,E., Williams,M.A., Saito,H., Mongodin,E. and Masri,R.
    Microbiological Profile and Human Immune Response Associated with Peri-Implantitis: A Systematic Review
    J Prosthodont PubMed  Europe PubMed DOI  V
  13. 2018
  14. Lu,J., Wang,M., Wang,Z., Fu,Z., Lu,A. and Zhang,G.
    Advances in the discovery of cathepsin K inhibitors on bone resorption
    J Enzyme Inhib Med Chem33, 890-904. PubMed  Europe PubMed DOI  V  I
  15. 2013
  16. Helali,A.M., Iti,F.M. and Mohamed,I.N.
    Cathepsin K inhibitors: a novel target but promising approach in the treatment of osteoporosis
    Curr Drug Targets14, 1591-1600. PubMed  Europe PubMed DOI  V  I
  17. Novinec,M. and Lenarcic,B.
    Cathepsin K: a unique collagenolytic cysteine peptidase
    Biol Chem394, 1163-1179. PubMed  Europe PubMed DOI  V
  18. 2011
  19. Costa,A.G., Cusano,N.E., Silva,B.C., Cremers,S. and Bilezikian,J.P.
    Cathepsin K: its skeletal actions and role as a therapeutic target in osteoporosis
    Nat Rev Rheumatol7, 447-456. PubMed  Europe PubMed DOI  V  I
  20. Xue,Y., Cai,T., Shi,S., Wang,W., Zhang,Y., Mao,T. and Duan,X.
    Clinical and animal research findings in pycnodysostosis and gene mutations of cathepsin K from 1996 to 2011
    Orphanet J Rare Dis6, 20-20. PubMed  Europe PubMed DOI  M  V
  21. 2010
  22. Kometani,M., Nonomura,K., Tomoo,T. and Niwa,S.
    Hurdles in the drug discovery of cathepsin K inhibitors
    Curr Top Med Chem10, 733-744. PubMed  Europe PubMed DOI  V  I
  23. Teno,N. and Masuya,K.
    Orally bioavailable cathepsin K inhibitors with pyrrolopyrimidine scaffold
    Curr Top Med Chem10, 752-766. PubMed  Europe PubMed DOI  V  I
  24. 2009
  25. Zhao,Q., Jia,Y. and Xiao,Y.
    Cathepsin K: a therapeutic target for bone diseases
    Biochem Biophys Res Commun380, 721-723. PubMed  Europe PubMed DOI  V
  26. 2008
  27. Lecaille,F., Bromme,D. and Lalmanach,G.
    Biochemical properties and regulation of cathepsin K activity
    Biochimie90, 208-226. PubMed  Europe PubMed DOI  V  T
  28. Stoch,S.A. and Wagner,J.A.
    Cathepsin K inhibitors: a novel target for osteoporosis therapy
    Clin Pharmacol Ther83, 172-176. PubMed  Europe PubMed DOI  V
  29. 2007
  30. Cameron Black,W. and David Percival,M.
    Chapter 8 Cathepsin K Inhibitors
    Annu Rep Med Chem42, 111-127. DOI  V
  31. 2005
  32. Cai,J.Q., Jamieson,C., Moir,J. and Rankovic,Z.
    Cathepsin K inhibitors, 2000-2004
    Expert Opin Ther Pat15, 33-48.  V
  33. Deaton,D.N. and Tavares,F.X.
    Design of cathepsin K inhibitors for osteoporosis
    Curr Top Med Chem5, 1639-1675. PubMed  Europe PubMed DOI  V  I
  34. Grabowskal,U., Chambers,T.J. and Shiroo,M.
    Recent developments in cathepsin K inhibitor design
    Curr Opin Drug Discov Devel8, 619-630. PubMed  Europe PubMed  V
  35. 2004
  36. Bromme,D.
    Cathepsin K
    [ISSN:0-12-079610-4]2, 1092-1097.  V
  37. Marquis,R.W.
    Inhibition of the cysteine protease cathepsin K (EC 3.4.22.38)
    Annu Rep Med Chem39, 79-98. DOI  V  I
  38. 1997
  39. Gowen,M.
    Inhibition of cathepsin K - a novel approach to antiresorptive therapy
    Expert Opin Investig Drugs6, 1199-1202. PubMed  Europe PubMed DOI  V