Literature for peptidase C01.036: cathepsin K

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

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    2018
  1. Roy,S., Das Chakraborty,S. and Biswas,S.
    Not all pycnodysostosis-related mutants of human cathepsin K are inactive - crystal structure and biochemical studies of an active mutant I249T
    FEBS J285, 4265-4280. PubMed  Europe PubMed DOI  M  S
  2. 2017
  3. Law,S., Andrault,P.M., Aguda,A.H., Nguyen,N.T., Kruglyak,N., Brayer,G.D. and Bromme,D.
    Identification of mouse cathepsin K structural elements that regulate the potency of odanacatib
    Biochem J474, 851-864. PubMed  Europe PubMed DOI  S  I
  4. 2014
  5. Novinec,M., Korenc,M., Caflisch,A., Ranganathan,R., Lenarcic,B. and Baici,A.
    A novel allosteric mechanism in the cysteine peptidase cathepsin K discovered by computational methods
    Nat Commun5, 3287-3287. PubMed  Europe PubMed DOI  S  I
  6. 2013
  7. Yuan,X.Y., Fu,D.Y., Ren,X.F., Fang,X., Wang,L., Zou,S. and Wu,Y.
    Highly selective aza-nitrile inhibitors for cathepsin K, structural optimization and molecular modeling
    Org Biomol Chem11, 5847-5852. PubMed  Europe PubMed DOI  S  I
  8. 2008
  9. Li,Z., Kienetz,M., Cherney,M.M., James,M.N. and Bromme,D.
    The crystal and molecular structures of a cathepsin K:chondroitin sulfate complex
    J Mol Biol383, 78-91. PubMed  Europe PubMed DOI  S
  10. 2005
  11. [YEAR:1-4-2005]Deaton,D.N., Hassell,A.M., McFadyen,R.B., Miller,A.B., Miller,L.R., Shewchuk,L.M., Tavares,F.X., Willard,D.H., Jr. and Wright,L.L.
    Novel and potent cyclic cyanamide-based cathepsin K inhibitors
    Bioorg Med Chem Lett15, 1815-1819. PubMed  Europe PubMed DOI  S  I
  12. [YEAR:1-12-2005]Palmer,J.T., Bryant,C., Wang,D.X., Davis,D.E., Setti,E.L., Rydzewski,R.M., Venkatraman,S., Tian,Z.Q., Burrill,L.C., Mendonca,R.V., Springman,E., McCarter,J., Chung,T., Cheung,H., Janc,J.W., McGrath,M., Somoza,J.R., Enriquez,P., Yu,Z.W., Strickley,R.M., Liu,L., Venuti,M.C., Percival,M.D., Falgueyret,J.P., Prasit,P., Oballa,R., Riendeau,D., Young,R.N., Wesolowski,G., Rodan,S.B., Johnson,C., Kimmel,D.B. and Rodan,G.
    Design and synthesis of tri-ring P3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K
    J Med Chem48, 7520-7534. PubMed  Europe PubMed DOI  S  I
  13. 2004
  14. [YEAR:18-11-2004]Altmann,E., Cowan-Jacob,S.W. and Missbach,M.
    Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K
    J Med Chem47, 5833-5836. PubMed  Europe PubMed DOI  S  I
  15. 2003
  16. [YEAR:30-12-2003]McGrath,M.E., Sprengeler,P.A., Hill,C.M., Martichonok,V., Cheung,H., Somoza,J.R., Palmer,J.T. and Janc,J.W.
    Peptide ketobenzoxazole inhibitors bound to cathepsin K
    Biochemistry42, 15018-15028. PubMed  Europe PubMed DOI  S  I
  17. 1999
  18. Sivaraman,J., Lalumiere,M., Menard,R. and Cygler,M.
    Crystal structure of wild-type human procathepsin K
    Protein Sci8, 283-290. PubMed  Europe PubMed DOI  S
  19. 1998
  20. [YEAR:5-11-1998]LaLonde,J.M., Zhao,B., Smith,W.W., Janson,C.A., DesJarlais,R.L., Tomaszek,T.A., Carr,T.J., Thompson,S.K., Oh,H.J., Yamashita,D.S., Veber,D.F. and Abdel-Meguid,S.S.
    Use of papain as a model for the structure-based design of cathepsin K inhibitors: crystal structures of two papain-inhibitor complexes demonstrate binding to S'-subsites
    J Med Chem41, 4567-4576. PubMed  Europe PubMed DOI  S  I
  21. 1997
  22. McGrath,M.E., Klaus,J.L., Barnes,M.G. and Bromme,D.
    Crystal structure of human cathepsin K complexed with a potent inhibitor
    Nat Struct Biol4, 105-109. PubMed  Europe PubMed DOI  S  I
  23. Zhao,B., Janson,C.A., Amegadzie,B.Y., D'Alessio,K., Griffin,C., Hanning,C.R., Jones,C., Kurdyla,J., McQueney,M., Qiu,X., Smith,W.W. and Abdel-Meguid,S.S.
    Crystal structure of human osteoclast cathepsin K complex with E-64
    Nat Struct Biol4, 109-111. PubMed  Europe PubMed DOI  S