Literature for peptidase C01.036: cathepsin K

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma

(References are filtered for relevance to Structure. To remove the filter click here. See explanation.)

    2018
  1. Roy,S., Das Chakraborty,S. and Biswas,S.
    Not all pycnodysostosis-related mutants of human cathepsin K are inactive - crystal structure and biochemical studies of an active mutant I249T
    FEBS J (2018) 285, 4265-4280. PubMed  Europe PubMed DOI  M  S
  2. 2017
  3. Law,S., Andrault,P.M., Aguda,A.H., Nguyen,N.T., Kruglyak,N., Brayer,G.D. and Bromme,D.
    Identification of mouse cathepsin K structural elements that regulate the potency of odanacatib
    Biochem J (2017) 474, 851-864. PubMed  Europe PubMed DOI  S  I
  4. 2014
  5. Novinec,M., Korenc,M., Caflisch,A., Ranganathan,R., Lenarcic,B. and Baici,A.
    A novel allosteric mechanism in the cysteine peptidase cathepsin K discovered by computational methods
    Nat Commun (2014) 5, 3287-3287. PubMed  Europe PubMed DOI  S  I
  6. 2013
  7. Yuan,X.Y., Fu,D.Y., Ren,X.F., Fang,X., Wang,L., Zou,S. and Wu,Y.
    Highly selective aza-nitrile inhibitors for cathepsin K, structural optimization and molecular modeling
    Org Biomol Chem (2013) 11, 5847-5852. PubMed  Europe PubMed DOI  S  I
  8. 2008
  9. Li,Z., Kienetz,M., Cherney,M.M., James,M.N. and Bromme,D.
    The crystal and molecular structures of a cathepsin K:chondroitin sulfate complex
    J Mol Biol (2008) 383, 78-91. PubMed  Europe PubMed DOI  S
  10. 2005
  11. [YEAR:1-4-2005]Deaton,D.N., Hassell,A.M., McFadyen,R.B., Miller,A.B., Miller,L.R., Shewchuk,L.M., Tavares,F.X., Willard,D.H., Jr. and Wright,L.L.
    Novel and potent cyclic cyanamide-based cathepsin K inhibitors
    Bioorg Med Chem Lett (1-4-2005) 15, 1815-1819. PubMed  Europe PubMed DOI  S  I
  12. [YEAR:1-12-2005]Palmer,J.T., Bryant,C., Wang,D.X., Davis,D.E., Setti,E.L., Rydzewski,R.M., Venkatraman,S., Tian,Z.Q., Burrill,L.C., Mendonca,R.V., Springman,E., McCarter,J., Chung,T., Cheung,H., Janc,J.W., McGrath,M., Somoza,J.R., Enriquez,P., Yu,Z.W., Strickley,R.M., Liu,L., Venuti,M.C., Percival,M.D., Falgueyret,J.P., Prasit,P., Oballa,R., Riendeau,D., Young,R.N., Wesolowski,G., Rodan,S.B., Johnson,C., Kimmel,D.B. and Rodan,G.
    Design and synthesis of tri-ring P3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K
    J Med Chem (1-12-2005) 48, 7520-7534. PubMed  Europe PubMed DOI  S  I
  13. 2004
  14. [YEAR:18-11-2004]Altmann,E., Cowan-Jacob,S.W. and Missbach,M.
    Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K
    J Med Chem (18-11-2004) 47, 5833-5836. PubMed  Europe PubMed DOI  S  I
  15. 2003
  16. [YEAR:30-12-2003]McGrath,M.E., Sprengeler,P.A., Hill,C.M., Martichonok,V., Cheung,H., Somoza,J.R., Palmer,J.T. and Janc,J.W.
    Peptide ketobenzoxazole inhibitors bound to cathepsin K
    Biochemistry (30-12-2003) 42, 15018-15028. PubMed  Europe PubMed DOI  S  I
  17. 1999
  18. Sivaraman,J., Lalumiere,M., Menard,R. and Cygler,M.
    Crystal structure of wild-type human procathepsin K
    Protein Sci (1999) 8, 283-290. PubMed  Europe PubMed DOI  PMC  EPMC  S
  19. 1998
  20. [YEAR:5-11-1998]LaLonde,J.M., Zhao,B., Smith,W.W., Janson,C.A., DesJarlais,R.L., Tomaszek,T.A., Carr,T.J., Thompson,S.K., Oh,H.J., Yamashita,D.S., Veber,D.F. and Abdel-Meguid,S.S.
    Use of papain as a model for the structure-based design of cathepsin K inhibitors: crystal structures of two papain-inhibitor complexes demonstrate binding to S'-subsites
    J Med Chem (5-11-1998) 41, 4567-4576. PubMed  Europe PubMed DOI  S  I
  21. 1997
  22. McGrath,M.E., Klaus,J.L., Barnes,M.G. and Bromme,D.
    Crystal structure of human cathepsin K complexed with a potent inhibitor
    Nat Struct Biol (1997) 4, 105-109. PubMed  Europe PubMed DOI  S  I
  23. Zhao,B., Janson,C.A., Amegadzie,B.Y., D'Alessio,K., Griffin,C., Hanning,C.R., Jones,C., Kurdyla,J., McQueney,M., Qiu,X., Smith,W.W. and Abdel-Meguid,S.S.
    Crystal structure of human osteoclast cathepsin K complex with E-64
    Nat Struct Biol (1997) 4, 109-111. PubMed  Europe PubMed DOI  S