$VAR1 = undef;

Summary for peptidase homologue T01.971: proteasome subunit alpha 6

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature

 

Names
MEROPS Nameproteasome subunit alpha 6
Other namesC7 g.p. (Saccharomyces cerevisiae), PRS2 g.p. (Saccharomyces cerevisiae), proteasome subunit iota (Homo sapiens), PSMA6 g.p. (Homo sapiens)
Domain architecture
MEROPS Classification
Classification Clan PB >> Subclan PB(T) >> Family T1 >> Subfamily A >> T01.971
Holotypeproteasome subunit alpha 6 (Homo sapiens), Uniprot accession P60900 (peptidase unit: 24-140), MERNUM MER0000557
History Identifier created: MEROPS 3.02 (25 June 1998)
Activity
Catalytic typeNon-peptidase homologue
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.25 (Threonine-type endopeptidases) >> Peptidase 3.4.25.1
EnzymologyBRENDA database
Activity statushuman: inactive
mouse: inactive
PhysiologyOne of the seven non-peptidase subunits of the 20 S proteasome, but homologous with the beta subunits, several of which express peptidase activity.
Pathways KEGGProteasome
Other databases TREEFAMhttp://www.treefam.org/family/TF106210
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
PSMA6 14q13 ENSG00000100902 5687 PSMA6 602855
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Psma6 12:C1 ENSMUSG00000021024 26443 MGI:1347006