$VAR1 = undef;
Summary for peptidase M12.235: ADAMTS10 peptidase
| Names | |
|---|---|
| MEROPS Name | ADAMTS10 peptidase |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan MA >> Subclan MA(M) >> Family M12 >> Subfamily B >> M12.235 |
| Holotype | ADAMTS10 peptidase (Homo sapiens), Uniprot accession Q9H324 (peptidase unit: 234-457), MERNUM MER0014331 |
| History | Identifier created: MEROPS 5.5 (16 June 2001) |
| Activity | |||
|---|---|---|---|
| Catalytic type | Metallo | ||
| NC-IUBMB | Not yet included in IUBMB recommendations. | ||
| Activity status | human: putative mouse: putative | ||
| Knockout | A study of the autosomal recessive Weill-Marchesani syndrome led to the conclusion that ADAMTS10 endopeptidase plays a major role in growth and in skin, lens, and heart development in humans (Dagoneau et al., 2004). | ||
| Other databases | WIKIPEDIA | http://en.wikipedia.org/wiki/ADAMTS10 | |
| Human genetics | ||||||
|---|---|---|---|---|---|---|
| Gene symbol | Locus | Megabases | Ensembl | Entrez gene | Gene Cards | OMIM |
| ADAMTS10 | 19p13.3 | ENSG00000142303 | 81794 | ADAMTS10 | ||
| Mouse genetics | ||||||
| Gene symbol | Position | Megabases | Ensembl | Entrez gene | MGI | |
| Adamts10 | 17:B1 | ENSMUSG00000024299 | 224697 | MGI:2449112 | ||
