Grimm C, Jungwirth S, Fischer U
To Be Published
- Mrna-capping enzyme regulatory subunit opg124 (33 kDa, Protein from Vaccinia virus)
- Vaccinia dna-directed rna polymerase open promoter intermediate pre-initiation complex (750 kDa, Complex)
- Dna-directed rna polymerase 18 kda subunit (17 kDa, Protein from Vaccinia virus)
- Intermediate transcription factor 3 small subunit (33 kDa, Protein from Vaccinia virus)
- Dna-directed rna polymerase 133 kda polypeptide (133 kDa, Protein from Vaccinia virus)
- Vaccinia dna-directed rna polymerase open promoter intermediate pre-initiation complex (Complex from Vaccinia virus)
- Dna-directed rna polymerase 147 kda polypeptide (146 kDa, Protein from Vaccinia virus)
- Dna-directed rna polymerase 22 kda subunit (21 kDa, Protein from Vaccinia virus)
- Template dna oligomer (21 kDa, DNA from Vaccinia virus)
- Dna-directed rna polymerase 7 kda subunit (7 kDa, Protein from Vaccinia virus)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase 30 kda polypeptide (29 kDa, Protein from Vaccinia virus)
- Intermediate transcription factor 3 large subunit (44 kDa, Protein from Vaccinia virus)
- Dna-directed rna polymerase 19 kda subunit (19 kDa, Protein from Vaccinia virus)
- Non-template dna oligomer and template dna oligomer (Complex from Vaccinia virus)
- Water (18 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerase 35 kda subunit (35 kDa, Protein from Vaccinia virus)
- Non-template dna oligomer (21 kDa, DNA from Vaccinia virus)
- Mrna-capping enzyme catalytic subunit (96 kDa, Protein from Vaccinia virus)
Grimm C, Jungwirth S, Fischer U
To Be Published
- Non-template dna oligomer (21 kDa, DNA from Vaccinia virus)
- Intermediate transcription factor 3 large subunit (44 kDa, Protein from Vaccinia virus)
- Intermediate transcription factor 3 small subunit (33 kDa, Protein from Vaccinia virus)
- Template dna oligomer (Complex from Vaccinia virus)
- Dna-directed rna polymerase 133 kda polypeptide (133 kDa, Protein from Vaccinia virus)
- Vaccinia dna-directed rna polymerase open promoter intermediate pre-initiation complex (Complex from Vaccinia virus)
- Dna-directed rna polymerase 147 kda polypeptide (146 kDa, Protein from Vaccinia virus)
- Dna-directed rna polymerase 19 kda subunit (19 kDa, Protein from Vaccinia virus)
- Mrna-capping enzyme catalytic subunit (96 kDa, Protein from Vaccinia virus)
- Dna-directed rna polymerase 22 kda subunit (21 kDa, Protein from Vaccinia virus)
- Vaccinia dna-directed rna polymerase open promoter intermediate pre-initiation complex (750 kDa, Complex)
- Template dna oligomer (21 kDa, DNA from Vaccinia virus)
- Dna-directed rna polymerase 7 kda subunit (7 kDa, Protein from Vaccinia virus)
- Magnesium ion (24 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase 30 kda polypeptide (29 kDa, Protein from Vaccinia virus)
- Dna-directed rna polymerase 35 kda subunit (35 kDa, Protein from Vaccinia virus)
- Dna-directed rna polymerase 18 kda subunit (17 kDa, Protein from Vaccinia virus)
Grimm C, Jungwirth S, Fischer U
To Be Published
- Mrna-capping enzyme regulatory subunit opg124 (33 kDa, Protein from Vaccinia virus)
- Intermediate transcription factor 3 large subunit (44 kDa, Protein from Vaccinia virus)
- Non-template dna oligomer (21 kDa, DNA from Vaccinia virus)
- Intermediate transcription factor 3 small subunit (33 kDa, Protein from Vaccinia virus)
- Dna-directed rna polymerase 133 kda polypeptide (133 kDa, Protein from Vaccinia virus)
- Dna-directed rna polymerase 19 kda subunit (19 kDa, Protein from Vaccinia virus)
- Dna-directed rna polymerase 147 kda polypeptide (146 kDa, Protein from Vaccinia virus)
- Zinc ion (65 Da, Ligand)
- Mrna-capping enzyme catalytic subunit (96 kDa, Protein from Vaccinia virus)
- Dna-directed rna polymerase 22 kda subunit (21 kDa, Protein from Vaccinia virus)
- Template dna oligomer (21 kDa, DNA from Vaccinia virus)
- Dna-directed rna polymerase 7 kda subunit (7 kDa, Protein from Vaccinia virus)
- Magnesium ion (24 Da, Ligand)
- Vaccinia dna-directed rna polymerase open promoter intermediate pre-initiation complex (750 kDa, Complex from Vaccinia virus)
- Dna-directed rna polymerase 30 kda polypeptide (29 kDa, Protein from Vaccinia virus)
- Dna-directed rna polymerase 35 kda subunit (35 kDa, Protein from Vaccinia virus)
- Dna-directed rna polymerase 18 kda subunit (17 kDa, Protein from Vaccinia virus)
RNA polymerase II core initially transcribing complex with an ordered RNA of 8 nt
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8s51
Q-score: 0.415
Zhan Y, Grabbe F, Oberbeckmann E, Dienemann C, Cramer P
Mol Cell (2024) 84 pp. 1699-1710.e6 [ DOI: doi:10.1016/j.molcel.2024.03.016 Pubmed: 38604172 ]
- Core initially transcribing complex with an ordered rna of 8 nt (Complex)
- Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Sus scrofa)
- General transcription factor iie subunit 1 (49 kDa, Protein from Homo sapiens)
- Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
- General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb11-a (13 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Sus scrofa)
- Tata-box-binding protein, transcription initiation factor iia (Complex from Homo sapiens)
- Transcription initiation factor iib (34 kDa, Protein from Homo sapiens)
- Rna (2 kDa, RNA from unidentified adenovirus)
- Zinc ion (65 Da, Ligand)
- Transcription initiation factor iib, iie and iif (Complex from Homo sapiens)
- Rna polymerase ii subunit k (7 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase subunit (217 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase subunit beta (147 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Sus scrofa)
- Transcription initiation factor iia subunit 1 (41 kDa, Protein from Homo sapiens)
- Template dna (42 kDa, DNA from unidentified adenovirus)
- Magnesium ion (24 Da, Ligand)
- Transcription initiation factor iie subunit beta (33 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Sus scrofa)
- General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Sus scrofa)
- Dna and rna (Complex from unidentified adenovirus)
- Rna polymerase ii subunit d (20 kDa, Protein from Sus scrofa)
- Rna polymerase ii (Complex from Sus scrofa)
- Transcription initiation factor iia subunit 2 (12 kDa, Protein from Homo sapiens)
- Non-template dna (43 kDa, DNA from unidentified adenovirus)
RNA polymerase II core initially transcribing complex with an ordered RNA of 10 nt
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8s52
Q-score: 0.431
Zhan Y, Grabbe F, Oberbeckmann E, Dienemann C, Cramer P
Mol Cell (2024) 84 pp. 1699-1710.e6 [ DOI: doi:10.1016/j.molcel.2024.03.016 Pubmed: 38604172 ]
- Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Sus scrofa)
- General transcription factor iie subunit 1 (49 kDa, Protein from Homo sapiens)
- Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
- Core initially transcribing complex with an ordered rna of 10 nt (Complex)
- General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb11-a (13 kDa, Protein from Sus scrofa)
- Transcription initiation factor iia (Complex from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Sus scrofa)
- Transcription initiation factor iib (34 kDa, Protein from Homo sapiens)
- Tata-box-binding protein, transcription initiation factor iib, iie and iif (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Rna polymerase ii subunit k (7 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase subunit (218 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase subunit beta (147 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Sus scrofa)
- Transcription initiation factor iia subunit 1 (41 kDa, Protein from Homo sapiens)
- Template dna (42 kDa, DNA from unidentified adenovirus)
- Magnesium ion (24 Da, Ligand)
- Transcription initiation factor iie subunit beta (33 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Sus scrofa)
- General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Sus scrofa)
- Rna (3 kDa, RNA from unidentified adenovirus)
- Dna and rna (Complex from unidentified adenovirus)
- Rna polymerase ii subunit d (20 kDa, Protein from Sus scrofa)
- Rna polymerase ii (Complex from Sus scrofa)
- Transcription initiation factor iia subunit 2 (12 kDa, Protein from Homo sapiens)
- Non-template dna (43 kDa, DNA from unidentified adenovirus)
RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state b (composite structure)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8s54
Q-score: 0.368
Zhan Y, Grabbe F, Oberbeckmann E, Dienemann C, Cramer P
Mol Cell (2024) 84 pp. 1699-1710.e6 [ DOI: doi:10.1016/j.molcel.2024.03.016 Pubmed: 38604172 ]
- Transcription factor iie subunit 1 and transcription factor iif (Complex from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Sus scrofa)
- Rna (4 kDa, RNA from unidentified adenovirus)
- General transcription factor iie subunit 1 (49 kDa, Protein from Homo sapiens)
- General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb11-a (13 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Rna polymerase ii subunit k (7 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase subunit (218 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase subunit beta (147 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Sus scrofa)
- Template dna (42 kDa, DNA from unidentified adenovirus)
- Rna polymerase ii early elongation complex bound to tfiie and tfiif - state b (Complex)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Sus scrofa)
- General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Sus scrofa)
- Dna and rna (Complex from unidentified adenovirus)
- Rna polymerase ii subunit d (20 kDa, Protein from Sus scrofa)
- Rna polymerase ii (Complex from Sus scrofa)
- Non-template dna (43 kDa, DNA from unidentified adenovirus)
RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state a (composite structure)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8s55
Q-score: 0.365
Zhan Y, Grabbe F, Oberbeckmann E, Dienemann C, Cramer P
Mol Cell (2024) 84 pp. 1699-1710.e6 [ DOI: doi:10.1016/j.molcel.2024.03.016 Pubmed: 38604172 ]
- Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Sus scrofa)
- Rna (4 kDa, RNA from unidentified adenovirus)
- General transcription factor iie subunit 1 (49 kDa, Protein from Homo sapiens)
- General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb11-a (13 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Rna polymerase ii subunit k (7 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase subunit (218 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase subunit beta (147 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Sus scrofa)
- Template dna (42 kDa, DNA from unidentified adenovirus)
- Magnesium ion (24 Da, Ligand)
- Transcription initiation factor iie subunit beta (33 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Sus scrofa)
- Rna polymerase ii early elongation complex bound to tfiie and tfiif - state a (Complex)
- Transcription factor iie and iif (Cell from Homo sapiens)
- General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Sus scrofa)
- Dna and rna (Complex from unidentified adenovirus)
- Rna polymerase ii subunit d (20 kDa, Protein from Sus scrofa)
- Rna polymerase ii (Complex from Sus scrofa)
- Non-template dna (43 kDa, DNA from unidentified adenovirus)
RNA polymerase II initially transcribing complex with an ordered RNA of 8 nt
Zhan Y, Grabbe F, Oberbeckmann E, Dienemann C, Cramer P
Mol Cell (2024) 84 pp. 1699-1710.e6 [ DOI: doi:10.1016/j.molcel.2024.03.016 Pubmed: 38604172 ]
RNA polymerase II initially transcribing complex with an ordered RNA of 10 nt
Zhan Y, Grabbe F, Oberbeckmann E, Dienemann C, Cramer P
Mol Cell (2024) 84 pp. 1699-1710.e6 [ DOI: doi:10.1016/j.molcel.2024.03.016 Pubmed: 38604172 ]
RNA polymerase II initially transcribing complex with an ordered RNA of 12 nt
Zhan Y, Grabbe F, Oberbeckmann E, Dienemann C, Cramer P
Mol Cell (2024) 84 pp. 1699-1710.e6 [ DOI: doi:10.1016/j.molcel.2024.03.016 Pubmed: 38604172 ]