Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"SARS-CoV-2 backtracked complex bound to nsp13 helicase - nsp13(1)-BTC"

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EMD-23007

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Structure of SARS-CoV-2 backtracked complex bound to nsp13 helicase - nsp13(1)-BTC

Release date: April 21, 2021
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7krn
Q-score: 0.476

Malone B, Chen J, Wang Q, Llewellyn E, Choi YJ, Olinares PDB, Cao X, Hernandez C, Eng ET, Chait BT, Shaw DE, Landick R, Darst SA, Campbell EA

PNAS (2021) 118 [ DOI: doi:10.1073/pnas.2102516118 Pubmed: 33883267 ]

Sample:

Sars-cov-2 backtracked complex bound to nsp13 helicase - nsp13(1)-btc (Complex from Severe acute respiratory syndrome coronavirus 2)
Chapso (631 Da, Ligand)
Non-structural protein 8 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Aluminum fluoride (83 Da, Ligand)
Rna-directed rna polymerase (106 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Rna (43-mer) (17 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
Adenosine-5'-diphosphate (427 Da, Ligand)
Magnesium ion (24 Da, Ligand)
Zinc ion (65 Da, Ligand)
Helicase (67 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Rna (37-mer) (12 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
Non-structural protein 7 (9 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)

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