Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"RAF1-HSP90-CDC37 complex, RHC-I"

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EMD-14473

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Structure of the RAF1-HSP90-CDC37 complex (RHC-I)

Release date: Sept. 14, 2022
Resolution: 3.16 Å
EM Method: Single-particle
Fitted PDBs: 7z38
Q-score: 0.447

Garcia-Alonso S, Mesa P, Ovejero LP, Aizpurua G, Lechuga CG, Zarzuela E, Santiveri CM, Sanclemente M, Munoz J, Musteanu M, Campos-Olivas R, Martinez-Torrecuadrada J, Barbacid M, Montoya G

Mol Cell (2022) 82 pp. 3438-3452.e8 [ DOI: doi:10.1016/j.molcel.2022.08.012 Pubmed: 36055235 ]

Sample:

Adenosine-5'-triphosphate (507 Da, Ligand)
Heat shock protein hsp 90-beta (84 kDa, Protein from Homo sapiens)
Raf1-hsp90-cdc37 complex, rhc-i (289 kDa, Complex from Homo sapiens)
Raf proto-oncogene serine/threonine-protein kinase (74 kDa, Protein from Homo sapiens)
Hsp90 co-chaperone cdc37 (46 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)

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