Structure of human KCNQ4-ML213 complex with PIP2
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 7vnp
Q-score: 0.376
Zheng Y, Liu H, Chen Y, Dong S, Wang F, Wang S, Li GL, Shu Y, Xu F
Neuron (2022) 110 pp. 237- [ Pubmed: 34767770 DOI: doi:10.1016/j.neuron.2021.10.029 ]
- Calmodulin-3 (16 kDa, Protein from Homo sapiens)
- Potassium voltage-gated channel subfamily kqt member 4,maltodextrin-binding protein (116 kDa, Protein from Escherichia coli (strain B / BL21-DE3))
- Kcnq4-ml213 complex with pip2 (Complex from Homo sapiens)
- (1s,2s,4r)-n-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid (257 Da, Ligand)
- [(2r)-1-octadecanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8z)-icosa-5,8,11,14-tetraenoate (1 kDa, Ligand)
- Potassium ion (39 Da, Ligand)
Structure of human KCNQ4-ML213 complex in nanodisc
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 7vnq
Q-score: 0.238
Zheng Y, Liu H, Chen Y, Dong S, Wang F, Wang S, Li GL, Shu Y, Xu F
Neuron (2022) 110 pp. 237- [ Pubmed: 34767770 DOI: doi:10.1016/j.neuron.2021.10.029 ]
- Calmodulin-3 (16 kDa, Protein from Homo sapiens)
- Potassium voltage-gated channel subfamily kqt member 4,maltodextrin-binding protein (116 kDa, Protein from Escherichia coli (strain B / BL21-DE3))
- Kcnq4-ml213 complex in nanodisc (Complex from Homo sapiens)
- (1s,2s,4r)-n-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid (257 Da, Ligand)
- Potassium ion (39 Da, Ligand)
Structure of human KCNQ4-ML213 complex in digitonin
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7vnr
Q-score: 0.27
Zheng Y, Liu H, Chen Y, Dong S, Wang F, Wang S, Li GL, Shu Y, Xu F
Neuron (2022) 110 pp. 237- [ Pubmed: 34767770 DOI: doi:10.1016/j.neuron.2021.10.029 ]
- Calmodulin-3 (16 kDa, Protein from Homo sapiens)
- Potassium voltage-gated channel subfamily kqt member 4,maltodextrin-binding protein (116 kDa, Protein from Escherichia coli (strain B / BL21-DE3))
- (1s,2s,4r)-n-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid (257 Da, Ligand)
- Kcnq4-ml213 complex in digitonin (Complex from Homo sapiens)
- Potassium ion (39 Da, Ligand)
Cryo-EM structure of human Apo CNGA1 channel in K+/Ca2+
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7lft
Q-score: 0.638
Xue J, Han Y, Zeng W, Wang Y, Jiang Y
Neuron (2021) 109 pp. 1302-1313.e4 [ Pubmed: 33651975 DOI: doi:10.1016/j.neuron.2021.02.007 ]
- Apo cnga1 homotetramer in k+/ca2+ (Cell from Homo sapiens)
- 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine (758 Da, Ligand)
- Water (18 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Cgmp-gated cation channel alpha-1 (64 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)