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sample_name:"NDUFB10"
Cryo-EM structure of Euglena gracilis super-complex I+III2+IV, composite
Release date: Feb. 28, 2024
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 8iuf
Q-score: 0.615
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 8iuf
Q-score: 0.615
He Z, Wu M, Tian H, Wang L, Hu Y, Han F, Zhou J, Wang Y, Zhou L
Nat Commun (2024) 15 pp. 1628-1628 [ Pubmed: 38388527 DOI: doi:10.1038/s41467-024-46018-z ]
Sample:
- Coxeg3 (16 kDa, Protein from Euglena gracilis)
- Uqcr9 (6 kDa, Protein from Euglena gracilis)
- Cardiolipin (1 kDa, Ligand)
- Ndufb10 (17 kDa, Protein from Euglena gracilis)
- Ndueg9 (18 kDa, Protein from Euglena gracilis)
- Ndufs1a (43 kDa, Protein from Euglena gracilis)
- Ndufs4 (23 kDa, Protein from Euglena gracilis)
- Ndufa5 (20 kDa, Protein from Euglena gracilis)
- Uqcrq (9 kDa, Protein from Euglena gracilis)
- Nduca1 (48 kDa, Protein from Euglena gracilis)
- Ndueg3 (63 kDa, Protein from Euglena gracilis)
- Uqcrh (8 kDa, Protein from Euglena gracilis)
- Ndufa13 (22 kDa, Protein from Euglena gracilis)
- Coxeg5 (19 kDa, Protein from Euglena gracilis)
- Cox7a (20 kDa, Protein from Euglena gracilis)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Mpp-beta (53 kDa, Protein from Euglena gracilis)
- Ndufs7 (22 kDa, Protein from Euglena gracilis)
- Ndufa8 (25 kDa, Protein from Euglena gracilis)
- Nd1 (79 kDa, Protein from Euglena gracilis)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Uqcrfs1 (27 kDa, Protein from Euglena gracilis)
- Ndueg10 (14 kDa, Protein from Euglena gracilis)
- Ndufs8 (24 kDa, Protein from Euglena gracilis)
- Ndufa7 (16 kDa, Protein from Euglena gracilis)
- Ndufb6 (10 kDa, Protein from Euglena gracilis)
- Ndufb11 (13 kDa, Protein from Euglena gracilis)
- Ndufab1-beta (14 kDa, Protein from Euglena gracilis)
- Ndufs3 (32 kDa, Protein from Euglena gracilis)
- Nduca3 (28 kDa, Protein from Euglena gracilis)
- Heme-a (852 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (56 kDa, Protein from Euglena gracilis)
- Euglena gracilis respirasome supercomplex i+iii2+iv (Complex from Euglena gracilis)
- Ndufa3 (14 kDa, Protein from Euglena gracilis)
- Cytochrome b (42 kDa, Protein from Euglena gracilis)
- 1,2-dilauroyl-sn-glycero-3-phosphate (535 Da, Ligand)
- Ubiquinol-cytochrome-c reductase complex subunit ix, mitochondrial (11 kDa, Protein from Euglena gracilis)
- Ndufs6 (17 kDa, Protein from Euglena gracilis)
- O-[(s)-hydroxy{[(2s)-2-hydroxy-3-(octadec-9-enoyloxy)propyl]oxy}phosphoryl]-l-serine (523 Da, Ligand)
- Ndueg5 (29 kDa, Protein from Euglena gracilis)
- Uqcrb (27 kDa, Protein from Euglena gracilis)
- Ndufa11 (32 kDa, Protein from Euglena gracilis)
- Cox7c (19 kDa, Protein from Euglena gracilis)
- Ndufa2 (21 kDa, Protein from Euglena gracilis)
- Cox4 (20 kDa, Protein from Euglena gracilis)
- Ndufa6 (48 kDa, Protein from Euglena gracilis)
- Ndueg6 (43 kDa, Protein from Euglena gracilis)
- Nd5 (68 kDa, Protein from Euglena gracilis)
- Ndufs5 (14 kDa, Protein from Euglena gracilis)
- Ndufa1 (15 kDa, Protein from Euglena gracilis)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Heme c (618 Da, Ligand)
- Ndufb5 (15 kDa, Protein from Euglena gracilis)
- Ndueg11 (11 kDa, Protein from Euglena gracilis)
- Ndufv1 (57 kDa, Protein from Euglena gracilis)
- Nd4l (19 kDa, Protein from Euglena gracilis)
- Ndufc2 (22 kDa, Protein from Euglena gracilis)
- Copper (ii) ion (63 Da, Ligand)
- Putative nadh dehydrogenase subunit 6 (19 kDa, Protein from Euglena gracilis)
- Ndufa9 (54 kDa, Protein from Euglena gracilis)
- Coxeg4 (19 kDa, Protein from Euglena gracilis)
- Cytochrome c oxidase subunit 2 (22 kDa, Protein from Euglena gracilis)
- Nd3 (34 kDa, Protein from Euglena gracilis)
- Uqcr10 (17 kDa, Protein from Euglena gracilis)
- Ndueg2 (51 kDa, Protein from Euglena gracilis)
- Nd2b (15 kDa, Protein from Euglena gracilis)
- Coxeg10 (10 kDa, Protein from Euglena gracilis)
- Ndueg1 (53 kDa, Protein from Euglena gracilis)
- Coxeg6 (8 kDa, Protein from Euglena gracilis)
- Ndueg7 (26 kDa, Protein from Euglena gracilis)
- Cox5c (23 kDa, Protein from Euglena gracilis)
- Cox6a (13 kDa, Protein from Euglena gracilis)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Ndufb2 (17 kDa, Protein from Euglena gracilis)
- Cox5b-2 (19 kDa, Protein from Euglena gracilis)
- Ndueg4 (41 kDa, Protein from Euglena gracilis)
- Ndufb8 (20 kDa, Protein from Euglena gracilis)
- Ndueg13 (17 kDa, Protein from Euglena gracilis)
- Nduca2 (28 kDa, Protein from Euglena gracilis)
- Ndufb9 (18 kDa, Protein from Euglena gracilis)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Coxeg1 (27 kDa, Protein from Euglena gracilis)
- Nd2a (35 kDa, Protein from Euglena gracilis)
- Zinc ion (65 Da, Ligand)
- Ndufb3 (6 kDa, Protein from Euglena gracilis)
- Cytochrome c oxidase subunit 1 (55 kDa, Protein from Euglena gracilis)
- Ndufab1-alpha (14 kDa, Protein from Euglena gracilis)
- Coxeg9 (31 kDa, Protein from Euglena gracilis)
- Ndueg11 (11 kDa, Protein from Euglena gracilis)
- Ndueg8 (23 kDa, Protein from Euglena gracilis)
- Ubiquinone-10 (863 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Ndufs1b (59 kDa, Protein from Euglena gracilis)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Ndufs2 (45 kDa, Protein from Euglena gracilis)
- Ndufb7 (12 kDa, Protein from Euglena gracilis)
- Magnesium ion (24 Da, Ligand)
- Cytochrome c1, heme protein (27 kDa, Protein from Euglena gracilis)
- Coxeg7 (35 kDa, Protein from Euglena gracilis)
- Ndufa12 (33 kDa, Protein from Euglena gracilis)
- Ndufx (37 kDa, Protein from Euglena gracilis)
- Ubiquinol-cytochrome-c reductase complex core protein 2, mitochondrial (51 kDa, Protein from Euglena gracilis)
- Cox6b-1 (32 kDa, Protein from Euglena gracilis)
- Ndufb4 (19 kDa, Protein from Euglena gracilis)
- Coxeg8 (24 kDa, Protein from Euglena gracilis)
- Euglena gracilis respirasome supercomplex i+iii2+iv (2 MDa, Complex from Euglena gracilis)
- Ndufv2 (25 kDa, Protein from Euglena gracilis)
- Poly(unk) (1 kDa, Protein from Euglena gracilis)
Cryo-EM composite map of Euglena gracilis respiratory complex I, deactive state
Release date: Feb. 28, 2024
Resolution: 3.11 Å
EM Method: Single-particle
Fitted PDBs: 8j9h
Q-score: 0.528
Resolution: 3.11 Å
EM Method: Single-particle
Fitted PDBs: 8j9h
Q-score: 0.528
He Z, Wu M, Tian H, Wang L, Hu Y, Han F, Zhou J, Wang Y, Zhou L
Nat Commun (2024) 15 pp. 1628-1628 [ Pubmed: 38388527 DOI: doi:10.1038/s41467-024-46018-z ]
Sample:
- Ndueg10 (14 kDa, Protein from Euglena gracilis)
- Ndueg13 (17 kDa, Protein from Euglena gracilis)
- Nduca2 (28 kDa, Protein from Euglena gracilis)
- Ndufb5 (15 kDa, Protein from Euglena gracilis)
- Ndueg11 (11 kDa, Protein from Euglena gracilis)
- Ndufb9 (18 kDa, Protein from Euglena gracilis)
- Nd2a (35 kDa, Protein from Euglena gracilis)
- Ndufv1 (57 kDa, Protein from Euglena gracilis)
- Ndufs8 (24 kDa, Protein from Euglena gracilis)
- Nd4l (19 kDa, Protein from Euglena gracilis)
- Ndueg2 (50 kDa, Protein from Euglena gracilis)
- Ndufa7 (16 kDa, Protein from Euglena gracilis)
- Ndufb6 (10 kDa, Protein from Euglena gracilis)
- Ndufb11 (13 kDa, Protein from Euglena gracilis)
- Ndufab1-beta (14 kDa, Protein from Euglena gracilis)
- Ndus1a (43 kDa, Protein from Euglena gracilis)
- Ndufs3 (32 kDa, Protein from Euglena gracilis)
- Zinc ion (65 Da, Ligand)
- Nduca3 (28 kDa, Protein from Euglena gracilis)
- Unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk (1 kDa, Protein from Euglena gracilis)
- Ndufc2 (22 kDa, Protein from Euglena gracilis)
- Cardiolipin (1 kDa, Ligand)
- Ndufb3 (6 kDa, Protein from Euglena gracilis)
- Nadh-ubiquinone oxidoreductase chain 4 (56 kDa, Protein from Euglena gracilis)
- Ndufa3 (14 kDa, Protein from Euglena gracilis)
- Ndufa9 (54 kDa, Protein from Euglena gracilis)
- Ndufab1-alpha (14 kDa, Protein from Euglena gracilis)
- Ndufb10 (17 kDa, Protein from Euglena gracilis)
- Ndufs4 (23 kDa, Protein from Euglena gracilis)
- Ndueg8 (23 kDa, Protein from Euglena gracilis)
- Ubiquinone-10 (863 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Ndufs6 (17 kDa, Protein from Euglena gracilis)
- Potassium ion (39 Da, Ligand)
- Ndufa5 (20 kDa, Protein from Euglena gracilis)
- Nduca1 (48 kDa, Protein from Euglena gracilis)
- Nd3 (34 kDa, Protein from Euglena gracilis)
- Ndueg5 (29 kDa, Protein from Euglena gracilis)
- Ndufa11 (32 kDa, Protein from Euglena gracilis)
- Ndueg1 (53 kDa, Protein from Euglena gracilis)
- Ndueg7 (26 kDa, Protein from Euglena gracilis)
- Ndufa13 (22 kDa, Protein from Euglena gracilis)
- Ndufa2 (21 kDa, Protein from Euglena gracilis)
- Ndufv2 (25 kDa, Protein from Euglena gracilis)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Ndufa6 (48 kDa, Protein from Euglena gracilis)
- Ndueg6 (43 kDa, Protein from Euglena gracilis)
- Nadh dehydrogenase subunit 5 (15 kDa, Protein from Euglena gracilis)
- Nd5 (68 kDa, Protein from Euglena gracilis)
- Ndufs2 (45 kDa, Protein from Euglena gracilis)
- Ndufs5 (14 kDa, Protein from Euglena gracilis)
- Ndufb7 (12 kDa, Protein from Euglena gracilis)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Ndufa1 (15 kDa, Protein from Euglena gracilis)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Ndufb2 (17 kDa, Protein from Euglena gracilis)
- Ndueg12 (11 kDa, Protein from Euglena gracilis)
- Ndufs7 (22 kDa, Protein from Euglena gracilis)
- Ndufa12 (33 kDa, Protein from Euglena gracilis)
- Ndueg3 (46 kDa, Protein from Euglena gracilis)
- Ndufa8 (25 kDa, Protein from Euglena gracilis)
- Ndus1b (59 kDa, Protein from Euglena gracilis)
- Euglena gracilis respiratory complex i, deactive state (1 MDa, Complex from Euglena gracilis)
- Ndufx (37 kDa, Protein from Euglena gracilis)
- Nd1 (79 kDa, Protein from Euglena gracilis)
- Ndufb4 (19 kDa, Protein from Euglena gracilis)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Ndueg4 (41 kDa, Protein from Euglena gracilis)
- Ndufb8 (20 kDa, Protein from Euglena gracilis)
Cryo-EM composite map of Euglena gracilis complex I, turnover state
Release date: Feb. 28, 2024
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 8j9i
Q-score: 0.584
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 8j9i
Q-score: 0.584
He Z, Wu M, Tian H, Wang L, Hu Y, Han F, Zhou J, Wang Y, Zhou L
Nat Commun (2024) 15 pp. 1628-1628 [ Pubmed: 38388527 DOI: doi:10.1038/s41467-024-46018-z ]
Sample:
- Ndueg10 (14 kDa, Protein from Euglena gracilis)
- Ndueg13 (17 kDa, Protein from Euglena gracilis)
- Nduca2 (28 kDa, Protein from Euglena gracilis)
- Ndufb5 (15 kDa, Protein from Euglena gracilis)
- Ndueg11 (11 kDa, Protein from Euglena gracilis)
- Euglena gracilis respiratory complex i, turnover state (1 MDa, Complex from Euglena gracilis)
- Ndufb9 (18 kDa, Protein from Euglena gracilis)
- Nd2a (35 kDa, Protein from Euglena gracilis)
- Ndufv1 (57 kDa, Protein from Euglena gracilis)
- Ndufs8 (24 kDa, Protein from Euglena gracilis)
- Nd4l (19 kDa, Protein from Euglena gracilis)
- Ndueg2 (50 kDa, Protein from Euglena gracilis)
- Ndufa7 (16 kDa, Protein from Euglena gracilis)
- Ndufb6 (10 kDa, Protein from Euglena gracilis)
- Ndufb11 (13 kDa, Protein from Euglena gracilis)
- Ndufab1-beta (14 kDa, Protein from Euglena gracilis)
- Zinc ion (65 Da, Ligand)
- Ndufs3 (32 kDa, Protein from Euglena gracilis)
- Nduca3 (28 kDa, Protein from Euglena gracilis)
- Unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk (1 kDa, Protein from Euglena gracilis)
- Ndufc2 (22 kDa, Protein from Euglena gracilis)
- Cardiolipin (1 kDa, Ligand)
- Ndufb3 (6 kDa, Protein from Euglena gracilis)
- Nadh-ubiquinone oxidoreductase chain 4 (56 kDa, Protein from Euglena gracilis)
- Ndufa3 (14 kDa, Protein from Euglena gracilis)
- Ndufa9 (54 kDa, Protein from Euglena gracilis)
- Ndufab1-alpha (14 kDa, Protein from Euglena gracilis)
- Ndufb10 (17 kDa, Protein from Euglena gracilis)
- Ndufs4 (23 kDa, Protein from Euglena gracilis)
- Ndueg8 (23 kDa, Protein from Euglena gracilis)
- Ubiquinone-10 (863 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Ndufs6 (17 kDa, Protein from Euglena gracilis)
- Potassium ion (39 Da, Ligand)
- Ndufa5 (20 kDa, Protein from Euglena gracilis)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Nduca1 (48 kDa, Protein from Euglena gracilis)
- Nd3 (34 kDa, Protein from Euglena gracilis)
- Ndueg5 (29 kDa, Protein from Euglena gracilis)
- Nd2b (15 kDa, Protein from Euglena gracilis)
- Ndufa11 (32 kDa, Protein from Euglena gracilis)
- Ndueg1 (53 kDa, Protein from Euglena gracilis)
- Ndueg7 (26 kDa, Protein from Euglena gracilis)
- Ndufa13 (22 kDa, Protein from Euglena gracilis)
- Ndufa2 (21 kDa, Protein from Euglena gracilis)
- Ndufv2 (25 kDa, Protein from Euglena gracilis)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Ndufs1b (59 kDa, Protein from Euglena gracilis)
- Ndufa6 (48 kDa, Protein from Euglena gracilis)
- Ndueg6 (43 kDa, Protein from Euglena gracilis)
- Nd5 (68 kDa, Protein from Euglena gracilis)
- Ndufs2 (45 kDa, Protein from Euglena gracilis)
- Ndufs5 (14 kDa, Protein from Euglena gracilis)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Ndufb7 (12 kDa, Protein from Euglena gracilis)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Ndufa1 (15 kDa, Protein from Euglena gracilis)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Ndufb2 (17 kDa, Protein from Euglena gracilis)
- Ndueg12 (11 kDa, Protein from Euglena gracilis)
- Ndufs1a (43 kDa, Protein from Euglena gracilis)
- Ndufs7 (22 kDa, Protein from Euglena gracilis)
- Ndufa12 (33 kDa, Protein from Euglena gracilis)
- Ndueg3 (46 kDa, Protein from Euglena gracilis)
- Ndufa8 (25 kDa, Protein from Euglena gracilis)
- Ndufx (37 kDa, Protein from Euglena gracilis)
- Nd1 (79 kDa, Protein from Euglena gracilis)
- Ndufb4 (19 kDa, Protein from Euglena gracilis)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Ndueg4 (41 kDa, Protein from Euglena gracilis)
- Ndufb8 (20 kDa, Protein from Euglena gracilis)
Cryo-EM composite map of Euglena gracilis complex I, NADH state
Release date: Feb. 28, 2024
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8j9j
Q-score: 0.531
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8j9j
Q-score: 0.531
He Z, Wu M, Tian H, Wang L, Hu Y, Han F, Zhou J, Wang Y, Zhou L
Nat Commun (2024) 15 pp. 1628-1628 [ Pubmed: 38388527 DOI: doi:10.1038/s41467-024-46018-z ]
Sample:
- Ndueg10 (14 kDa, Protein from Euglena gracilis)
- Ndueg13 (17 kDa, Protein from Euglena gracilis)
- Nduca2 (28 kDa, Protein from Euglena gracilis)
- Ndufb5 (15 kDa, Protein from Euglena gracilis)
- Ndueg11 (11 kDa, Protein from Euglena gracilis)
- Ndufb9 (18 kDa, Protein from Euglena gracilis)
- Nd2a (35 kDa, Protein from Euglena gracilis)
- Ndufv1 (57 kDa, Protein from Euglena gracilis)
- Ndufs8 (24 kDa, Protein from Euglena gracilis)
- Nd4l (19 kDa, Protein from Euglena gracilis)
- Ndueg2 (50 kDa, Protein from Euglena gracilis)
- Ndufa7 (16 kDa, Protein from Euglena gracilis)
- Ndufb6 (10 kDa, Protein from Euglena gracilis)
- Ndufb11 (13 kDa, Protein from Euglena gracilis)
- Ndufab1-beta (14 kDa, Protein from Euglena gracilis)
- Zinc ion (65 Da, Ligand)
- Ndufs3 (32 kDa, Protein from Euglena gracilis)
- Nduca3 (28 kDa, Protein from Euglena gracilis)
- Unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk (1 kDa, Protein from Euglena gracilis)
- Ndufc2 (22 kDa, Protein from Euglena gracilis)
- Cardiolipin (1 kDa, Ligand)
- Ndufb3 (6 kDa, Protein from Euglena gracilis)
- Euglena gracilis respiratory complex i, nadh state (1 MDa, Complex from Euglena gracilis)
- Nadh-ubiquinone oxidoreductase chain 4 (56 kDa, Protein from Euglena gracilis)
- Ndufa3 (14 kDa, Protein from Euglena gracilis)
- Ndufa9 (54 kDa, Protein from Euglena gracilis)
- Ndufab1-alpha (14 kDa, Protein from Euglena gracilis)
- Ndufb10 (17 kDa, Protein from Euglena gracilis)
- Ndufs4 (23 kDa, Protein from Euglena gracilis)
- Ndueg8 (23 kDa, Protein from Euglena gracilis)
- Ubiquinone-10 (863 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Ndufs6 (17 kDa, Protein from Euglena gracilis)
- Potassium ion (39 Da, Ligand)
- Ndufa5 (20 kDa, Protein from Euglena gracilis)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Nduca1 (48 kDa, Protein from Euglena gracilis)
- Nd3 (34 kDa, Protein from Euglena gracilis)
- Ndueg5 (29 kDa, Protein from Euglena gracilis)
- Nd2b (15 kDa, Protein from Euglena gracilis)
- Ndufa11 (32 kDa, Protein from Euglena gracilis)
- Ndueg1 (53 kDa, Protein from Euglena gracilis)
- Ndueg7 (26 kDa, Protein from Euglena gracilis)
- Ndufa13 (22 kDa, Protein from Euglena gracilis)
- Ndufa2 (21 kDa, Protein from Euglena gracilis)
- Ndufv2 (25 kDa, Protein from Euglena gracilis)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Ndufs1b (59 kDa, Protein from Euglena gracilis)
- Ndufa6 (48 kDa, Protein from Euglena gracilis)
- Ndueg6 (43 kDa, Protein from Euglena gracilis)
- Nd5 (68 kDa, Protein from Euglena gracilis)
- Ndufs2 (45 kDa, Protein from Euglena gracilis)
- Ndufs5 (14 kDa, Protein from Euglena gracilis)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Ndufb7 (12 kDa, Protein from Euglena gracilis)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Ndufa1 (15 kDa, Protein from Euglena gracilis)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Ndufb2 (17 kDa, Protein from Euglena gracilis)
- Ndueg12 (11 kDa, Protein from Euglena gracilis)
- Ndufs1a (43 kDa, Protein from Euglena gracilis)
- Ndufs7 (22 kDa, Protein from Euglena gracilis)
- Ndufa12 (33 kDa, Protein from Euglena gracilis)
- Ndueg3 (46 kDa, Protein from Euglena gracilis)
- Ndufa8 (25 kDa, Protein from Euglena gracilis)
- Ndufx (37 kDa, Protein from Euglena gracilis)
- Nd1 (79 kDa, Protein from Euglena gracilis)
- Ndufb4 (19 kDa, Protein from Euglena gracilis)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Ndueg4 (41 kDa, Protein from Euglena gracilis)
- Ndufb8 (20 kDa, Protein from Euglena gracilis)
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM)
Release date: Nov. 30, 2022
Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 7zm7
Q-score: 0.598
Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 7zm7
Q-score: 0.598
Laube E, Meier-Credo J, Langer JD, Kuhlbrandt W
Sci Adv (2022) 8 pp. eadc9952-eadc9952 [ DOI: doi:10.1126/sciadv.adc9952 Pubmed: 36427319 ]
Sample:
- Nadh dehydrogenase subunit 2 (64 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb3 of nadh-ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb10 of nadh-ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 3 (16 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Mitochondrial nadh:ubiquinone oxidoreductase in ddm (970 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Oxidoreductase-like protein (25 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (23 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (29 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase 49 kda subunit-like protein (55 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Oxidoreductase-like domain-containing protein (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (82 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Cardiolipin (1 kDa, Ligand)
- Subunit ndufb2 of nadh-ubiquinone oxidoreductase (complex i) (5 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (43 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb4 of nadh-ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (23 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4 (60 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Flavin mononucleotide (456 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Water (18 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (24 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-b22 (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase 30.4 kda subunit-like protein (33 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb6 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (18 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase b14 subunit-like protein (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Subunit ndufb5 of nadh-ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (25 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Subunit ndufs5 of nadh-ubiquinone oxidoreductase (complex i) (87 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa3 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufv2 of nadh-ubiquinone oxidoreductase (complex i) (35 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Acyl carrier protein (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-esss (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufc2 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 5 (75 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase-like protein (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (55 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- Subunit ndufa1 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
Release date: Nov. 30, 2022
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 7zm8
Q-score: 0.604
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 7zm8
Q-score: 0.604
Laube E, Meier-Credo J, Langer JD, Kuhlbrandt W
Sci Adv (2022) 8 pp. eadc9952-eadc9952 [ DOI: doi:10.1126/sciadv.adc9952 Pubmed: 36427319 ]
Sample:
- Nadh dehydrogenase subunit 2 (64 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb3 of nadh-ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb10 of nadh-ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 3 (16 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Mitochondrial nadh:ubiquinone oxidoreductase in ddm (970 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (89 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Cardiolipin (1 kDa, Ligand)
- Subunit ndufb2 of nadh-ubiquinone oxidoreductase (complex i) (5 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb4 of nadh-ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4 (60 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Water (18 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (24 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-b22 (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb6 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Subunit ndufb5 of nadh-ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufs5 of nadh-ubiquinone oxidoreductase (complex i) (87 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa3 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Acyl carrier protein (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-esss (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufc2 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 5 (75 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- Subunit ndufa1 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 2)
Release date: Nov. 30, 2022
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 7zmb
Q-score: 0.598
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 7zmb
Q-score: 0.598
Laube E, Meier-Credo J, Langer JD, Kuhlbrandt W
Sci Adv (2022) 8 pp. eadc9952-eadc9952 [ DOI: doi:10.1126/sciadv.adc9952 Pubmed: 36427319 ]
Sample:
- Nadh dehydrogenase subunit 2 (64 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Mitochondrial nadh:ubiquinone oxidoreductase in lmng (970 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb3 of nadh-ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb10 of nadh-ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 3 (16 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Oxidoreductase-like protein (25 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (23 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (29 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase 49 kda subunit-like protein (55 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Oxidoreductase-like domain-containing protein (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (82 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Cardiolipin (1 kDa, Ligand)
- Subunit ndufb2 of nadh-ubiquinone oxidoreductase (complex i) (5 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (43 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb4 of nadh-ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (23 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4 (60 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Flavin mononucleotide (456 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Water (18 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (24 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-b22 (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase 30.4 kda subunit-like protein (33 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Subunit ndufb6 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (18 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase b14 subunit-like protein (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Subunit ndufb5 of nadh-ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (25 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Subunit ndufs5 of nadh-ubiquinone oxidoreductase (complex i) (87 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa3 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufv2 of nadh-ubiquinone oxidoreductase (complex i) (35 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Acyl carrier protein (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-esss (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufc2 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 5 (75 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase-like protein (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (55 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Subunit ndufa1 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 2) - membrane arm
Release date: Nov. 30, 2022
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 7zme
Q-score: 0.596
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 7zme
Q-score: 0.596
Laube E, Meier-Credo J, Langer JD, Kuhlbrandt W
Sci Adv (2022) 8 pp. eadc9952-eadc9952 [ DOI: doi:10.1126/sciadv.adc9952 Pubmed: 36427319 ]
Sample:
- Nadh dehydrogenase subunit 2 (64 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Mitochondrial nadh:ubiquinone oxidoreductase in lmng (970 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb3 of nadh-ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb10 of nadh-ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 3 (16 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (89 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Cardiolipin (1 kDa, Ligand)
- Subunit ndufb2 of nadh-ubiquinone oxidoreductase (complex i) (5 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb4 of nadh-ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4 (60 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Water (18 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (24 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-b22 (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Subunit ndufb6 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Subunit ndufb5 of nadh-ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufs5 of nadh-ubiquinone oxidoreductase (complex i) (87 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa3 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Acyl carrier protein (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-esss (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufc2 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 5 (75 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa1 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1)
Release date: Nov. 30, 2022
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 7zmg
Q-score: 0.667
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 7zmg
Q-score: 0.667
Laube E, Meier-Credo J, Langer JD, Kuhlbrandt W
Sci Adv (2022) 8 pp. eadc9952-eadc9952 [ DOI: doi:10.1126/sciadv.adc9952 Pubmed: 36427319 ]
Sample:
- Nadh dehydrogenase subunit 2 (64 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Mitochondrial nadh:ubiquinone oxidoreductase in lmng (970 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb3 of nadh-ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb10 of nadh-ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 3 (16 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Oxidoreductase-like protein (25 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (23 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (29 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase 49 kda subunit-like protein (55 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Oxidoreductase-like domain-containing protein (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (82 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Cardiolipin (1 kDa, Ligand)
- Subunit ndufb2 of nadh-ubiquinone oxidoreductase (complex i) (5 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (43 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb4 of nadh-ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (23 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4 (60 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Flavin mononucleotide (456 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Water (18 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (24 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-b22 (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase 30.4 kda subunit-like protein (33 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Subunit ndufb6 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (18 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase b14 subunit-like protein (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Subunit ndufb5 of nadh-ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (25 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Subunit ndufs5 of nadh-ubiquinone oxidoreductase (complex i) (87 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa3 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufv2 of nadh-ubiquinone oxidoreductase (complex i) (35 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Acyl carrier protein (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-esss (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufc2 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 5 (75 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase-like protein (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (55 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Subunit ndufa1 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1) - membrane arm
Release date: Nov. 30, 2022
Resolution: 2.47 Å
EM Method: Single-particle
Fitted PDBs: 7zmh
Q-score: 0.672
Resolution: 2.47 Å
EM Method: Single-particle
Fitted PDBs: 7zmh
Q-score: 0.672
Laube E, Meier-Credo J, Langer JD, Kuhlbrandt W
Sci Adv (2022) 8 pp. eadc9952-eadc9952 [ DOI: doi:10.1126/sciadv.adc9952 Pubmed: 36427319 ]
Sample:
- Nadh dehydrogenase subunit 2 (64 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Mitochondrial nadh:ubiquinone oxidoreductase in lmng (970 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb3 of nadh-ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb10 of nadh-ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 3 (16 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (89 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Cardiolipin (1 kDa, Ligand)
- Subunit ndufb2 of nadh-ubiquinone oxidoreductase (complex i) (5 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb4 of nadh-ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4 (60 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Water (18 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (24 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-b22 (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Subunit ndufb6 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Subunit ndufb5 of nadh-ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufs5 of nadh-ubiquinone oxidoreductase (complex i) (87 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa3 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Acyl carrier protein (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-esss (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufc2 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 5 (75 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa1 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)