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sample_name:"NADH-ubiquinone oxidoreductase chain 3" AND author_orcid:"0000-0002-8838-3151"
Release date: March 29, 2023
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8b6f
Q-score: 0.463
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8b6f
Q-score: 0.463
Muhleip A, Flygaard RK, Baradaran R, Haapanen O, Gruhl T, Tobiasson V, Marechal A, Sharma V, Amunts A
Nature (2023) 615 pp. 934-938 [ Pubmed: 36949187 DOI: doi:10.1038/s41586-023-05817-y ]
Sample:
- Acyl carrier protein (15 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (9 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (8 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 7 (51 kDa, Protein from Tetrahymena thermophila SB210)
- Cx9c domain-containing protein (28 kDa, Protein from Tetrahymena thermophila SB210)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Ndub10 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Cox assembly mitochondrial protein (17 kDa, Protein from Tetrahymena thermophila SB210)
- Gamma-carbonic anhydrase (28 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf62 (30 kDa, Protein from Tetrahymena thermophila SB210)
- Chch domain-containing protein (13 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (52 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (23 kDa, Protein from Tetrahymena thermophila SB210)
- Atp synthase subunit e, mitochondrial (11 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 10 (18 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase 24 kda subunit (31 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase complex i, 21 kda subunit (17 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase chain 3 (14 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (24 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (8 kDa, Protein from Tetrahymena thermophila SB210)
- Iron/sulfur cluster (351 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Transmembrane protein, putative (26 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (21 kDa, Protein from Tetrahymena thermophila SB210)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase 75 kda subunit (80 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub4 (14 kDa, Protein from Tetrahymena thermophila SB210)
- Ndutt16 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Cardiolipin (1 kDa, Ligand)
- Transmembrane protein, putative (11 kDa, Protein from Tetrahymena thermophila SB210)
- 2 iron, 2 sulfur cluster-binding protein (19 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (16 kDa, Protein from Tetrahymena thermophila SB210)
- Ndutt15 (25 kDa, Protein from Tetrahymena thermophila SB210)
- Gamma-carbonic anhydrase (25 kDa, Protein from Tetrahymena thermophila SB210)
- Lipid-a-disaccharide synthase (59 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub8 (24 kDa, Protein from Tetrahymena thermophila SB210)
- Acyl carrier protein (16 kDa, Protein from Tetrahymena thermophila SB210)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Ph domain-containing protein (15 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (13 kDa, Protein from Tetrahymena thermophila SB210)
- Nd1b (7 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 9 (23 kDa, Protein from Tetrahymena thermophila SB210)
- Rnase iii domain-containing protein (35 kDa, Protein from Tetrahymena thermophila SB210)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Complex i-mnll (12 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (22 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (29 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf58 (13 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Nduph2 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Gram domain protein (10 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf65 (43 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein (24 kDa, Protein from Tetrahymena thermophila SB210)
- Magnesium ion (24 Da, Ligand)
- Ymf57 (12 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase, putative (20 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase chain 4 (58 kDa, Protein from Tetrahymena thermophila SB210)
- Dnaj domain protein (36 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh:ubiquinone oxidoreductase complex (complex-i) from respiratory supercomplex of tetrahymena thermophila (1 MDa, Complex from Tetrahymena thermophila)
- Nadh dehydrogenase subunit 2 (20 kDa, Protein from Tetrahymena thermophila SB210)
- Nad-dependent epimerase/dehydratase family protein (41 kDa, Protein from Tetrahymena thermophila SB210)
- Acyl-coa synthetase (amp-forming)/amp-acid ligase ii (36 kDa, Protein from Tetrahymena thermophila SB210)
- Ndua13 (21 kDa, Protein from Tetrahymena thermophila SB210)
- Zinc-finger protein (15 kDa, Protein from Tetrahymena thermophila SB210)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Transcription factor apfi protein, putative (39 kDa, Protein from Tetrahymena thermophila SB210)
- Ribosomal protein l51/s25/ci-b8 domain protein (12 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Tetrahymena thermophila SB210)
- 37s ribosomal protein s25, mitochondrial (33 kDa, Protein from Tetrahymena thermophila SB210)
- Ndutt17 (13 kDa, Protein from Tetrahymena thermophila SB210)
- 2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate (648 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Etc complex i subunit motif protein (24 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub6 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase chain 1 (32 kDa, Protein from Tetrahymena thermophila SB210)
- Thioredoxin (19 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub15 (14 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 5 (88 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase 1, chain, putative (28 kDa, Protein from Tetrahymena thermophila SB210)
- Uridine-5'-diphosphate (404 Da, Ligand)
Cryo-EM structure of respiratory complex I under turnover
Release date: Nov. 10, 2021
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7o6y
Q-score: 0.468
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7o6y
Q-score: 0.468
Parey K, Lasham J, Mills DJ, Djurabekova A, Haapanen O, Yoga EG, Xie H, Kuhlbrandt W, Sharma V, Vonck J, Zickermann V
Sci Adv (2021) 7 pp. eabj3221-eabj3221 [ Pubmed: 34767441 DOI: doi:10.1126/sciadv.abj3221 ]
Sample:
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (53 kDa, Protein from Candida lipolytica)
- Subunit ni8m of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Candida lipolytica)
- Subunit nupm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Subunit nuxm of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Candida lipolytica)
- Nadh-ubiquinone oxidoreductase chain 3 (14 kDa, Protein from Yarrowia lipolytica)
- Cardiolipin (1 kDa, Ligand)
- Subunit nimm of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Candida lipolytica)
- Subunit nuim of nadh:ubiquinone oxidoreductase (complex i) (25 kDa, Protein from Candida lipolytica)
- Nadh-ubiquinone oxidoreductase chain 1 (38 kDa, Protein from Yarrowia lipolytica)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Subunit nb4m of protein nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Candida lipolytica)
- Subunit nuzm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Subunit nugm of nadh:ubiquinone oxidoreductase (complex i) (32 kDa, Protein from Candida lipolytica)
- Subunit nuem of nadh:ubiquinone oxidoreductase (complex i) (42 kDa, Protein from Yarrowia lipolytica)
- Diundecyl phosphatidyl choline (622 Da, Ligand)
- Subunit ni2m of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Candida lipolytica)
- Subunit nujm of nadh:ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Yarrowia lipolytica)
- Phosphatidylinositol (887 Da, Ligand)
- Subunit niam of nadh:ubiquinone oxidoreductase (complex i) (17 kDa, Protein from Yarrowia lipolytica)
- Subunit nebm of nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Acyl carrier protein acpm1 of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Candida lipolytica)
- Mitochondrial nadh:ubiquinone oxidoreductase (1 MDa, Complex from Yarrowia lipolytica)
- Zinc ion (65 Da, Ligand)
- Subunit nunm of nadh:ubiquinone oxidoreductase (complex i) (15 kDa, Protein from Candida lipolytica)
- Nucm protein (52 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 6 (20 kDa, Protein from Candida lipolytica)
- 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine (758 Da, Ligand)
- Subunit nuhm of nadh:ubiquinone oxidoreductase (complex i) (27 kDa, Protein from Candida lipolytica)
- Ubiquinone-9 (795 Da, Ligand)
- Acyl carrier protein acpm2 of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Candida lipolytica)
- Subunit nuvm of nadh:ubiquinone oxidoreductase (complex i) (7 kDa, Protein from Yarrowia lipolytica)
- Subunit nuym of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Candida lipolytica)
- Subunit n7bm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nb8m of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Candida lipolytica)
- Subunit nipm of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Candida lipolytica)
- Subunit ni9m of protein nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Subunit nufm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nb6m of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Candida lipolytica)
- Subunit nuam of nadh:ubiquinone oxidoreductase (complex i) (79 kDa, Protein from Candida lipolytica)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Subunit nu5m of nadh:ubiquinone oxidoreductase (complex i) (73 kDa, Protein from Yarrowia lipolytica)
- Subunit nesm of nadh:ubiquinone oxidoreductase (complex i) (28 kDa, Protein from Yarrowia lipolytica)
- Subunit numm of protein nadh:ubiquinone oxidoreductase (complex i) (15 kDa, Protein from Candida lipolytica)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Subunit nukm of nadh:ubiquinone oxidoreductase (complex i) (23 kDa, Protein from Candida lipolytica)
- Subunit nu4m of nadh:ubiquinone oxidoreductase (complex i) (54 kDa, Protein from Yarrowia lipolytica)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Subunit nuum of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nidm of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Candida lipolytica)
- Subunit nb5m of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Candida lipolytica)
- Subunit nb2m of nadh:ubiquinone oxidoreductase (complex i) (6 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Yarrowia lipolytica)
- Nadh dehydrogenase subunit 2 (53 kDa, Protein from Yarrowia lipolytica)
Cryo-EM structure of a respiratory complex I
Release date: Nov. 10, 2021
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 7o71
Q-score: 0.644
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 7o71
Q-score: 0.644
Parey K, Lasham J, Mills DJ, Djurabekova A, Haapanen O, Yoga EG, Xie H, Kuhlbrandt W, Sharma V, Vonck J, Zickermann V
Sci Adv (2021) 7 pp. eabj3221-eabj3221 [ Pubmed: 34767441 DOI: doi:10.1126/sciadv.abj3221 ]
Sample:
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (53 kDa, Protein from Candida lipolytica)
- Subunit ni8m of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Candida lipolytica)
- Subunit nupm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Subunit nuxm of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Candida lipolytica)
- Nadh-ubiquinone oxidoreductase chain 3 (14 kDa, Protein from Yarrowia lipolytica)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase 78 kda subunit (79 kDa, Protein from Candida lipolytica)
- Subunit nimm of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Candida lipolytica)
- Subunit nuim of nadh:ubiquinone oxidoreductase (complex i) (25 kDa, Protein from Candida lipolytica)
- Nadh-ubiquinone oxidoreductase chain 1 (38 kDa, Protein from Yarrowia lipolytica)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Subunit nb4m of protein nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Candida lipolytica)
- Subunit nuzm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Subunit nugm of nadh:ubiquinone oxidoreductase (complex i) (32 kDa, Protein from Candida lipolytica)
- Diundecyl phosphatidyl choline (622 Da, Ligand)
- Subunit ni2m of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Candida lipolytica)
- Subunit nujm of nadh:ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Yarrowia lipolytica)
- Phosphatidylinositol (887 Da, Ligand)
- Subunit niam of nadh:ubiquinone oxidoreductase (complex i) (17 kDa, Protein from Yarrowia lipolytica)
- Subunit nebm of nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 4 (54 kDa, Protein from Yarrowia lipolytica)
- Acyl carrier protein acpm1 of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Candida lipolytica)
- Mitochondrial nadh:ubiquinone oxidoreductase (1 MDa, Complex from Yarrowia lipolytica)
- Zinc ion (65 Da, Ligand)
- Nucm protein (52 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase 40 kda subunit (42 kDa, Protein from Candida lipolytica)
- Nadh-ubiquinone oxidoreductase chain 6 (20 kDa, Protein from Candida lipolytica)
- 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine (758 Da, Ligand)
- Subunit nuhm of nadh:ubiquinone oxidoreductase (complex i) (27 kDa, Protein from Candida lipolytica)
- Subunit nunm of nadh:ubiquinone oxidoreductase (complex i) (13 kDa, Protein from Candida lipolytica)
- Water (18 Da, Ligand)
- Acyl carrier protein acpm2 of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Candida lipolytica)
- Subunit nuvm of nadh:ubiquinone oxidoreductase (complex i) (7 kDa, Protein from Yarrowia lipolytica)
- Subunit nuym of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Candida lipolytica)
- Subunit n7bm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nb8m of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Candida lipolytica)
- Subunit nipm of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Candida lipolytica)
- Subunit ni9m of protein nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Subunit nufm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nb6m of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Candida lipolytica)
- Iron/sulfur cluster (351 Da, Ligand)
- Subunit nesm of nadh:ubiquinone oxidoreductase (complex i) (28 kDa, Protein from Yarrowia lipolytica)
- Subunit numm of protein nadh:ubiquinone oxidoreductase (complex i) (15 kDa, Protein from Candida lipolytica)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Subunit nukm of nadh:ubiquinone oxidoreductase (complex i) (23 kDa, Protein from Candida lipolytica)
- Nadh-ubiquinone oxidoreductase chain 5 (73 kDa, Protein from Yarrowia lipolytica)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Subunit nuum of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nidm of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Candida lipolytica)
- Subunit nb5m of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Candida lipolytica)
- Subunit nb2m of nadh:ubiquinone oxidoreductase (complex i) (6 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Yarrowia lipolytica)
- Nadh dehydrogenase subunit 2 (53 kDa, Protein from Yarrowia lipolytica)