Do data resources managed by EMBL-EBI and our collaborators make a difference to your work? Please take 10 minutes to fill in our annual user survey, and help us make the case for why sustaining open data resources is critical for life sciences research.
Matrix arm of active state CI from Q1-NADH dataset
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 7vyn
Q-score: 0.681
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Water (18 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (12 kDa, Protein from pig)
- Magnesium ion (24 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Acyl carrier protein, mitochondrial (10 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (24 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (44 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Ubiquinone-1 (250 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (3 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
Matrix arm of deactive state CI from Q1-NADH dataset
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7vz1
Q-score: 0.665
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Water (18 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit a9 (38 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (5 kDa, Protein from pig)
- Magnesium ion (24 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Respiratory complex i (Complex from Sus scrofa)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (24 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (44 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (3 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
Matrix arm of active state CI from Q10-NADH dataset
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7vy8
Q-score: 0.645
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Nadh-ubiquinone oxidoreductase 13 kda-b subunit (12 kDa, Protein from pig)
- Magnesium ion (24 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase 30 kda subunit (24 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (44 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 9 kda subunit (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (3 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
Membrane arm of active state CI from Q10-NADH dataset
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7vy9
Q-score: 0.604
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (5 kDa, Protein from pig)
- Respiratory complex i (Complex from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from pig)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (15 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (13 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (8 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 3 (12 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from pig)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from pig)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from pig)
Matrix arm of deactive state CI from Q10-NADH dataset
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7vya
Q-score: 0.597
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3 (5 kDa, Protein from pig)
- Magnesium ion (24 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Respiratory complex i (Complex from Sus scrofa)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (44 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3 (24 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (3 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
Membrane arm of active state CI from Q1-NADH dataset
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7vys
Q-score: 0.657
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Water (18 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (15 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (5 kDa, Protein from pig)
- Respiratory complex i (Complex from Sus scrofa)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Acyl carrier protein, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (13 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (8 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 3 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from pig)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from pig)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Tyrosine (181 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from pig)
Matrix arm of active state CI from Q10 dataset
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7vxp
Q-score: 0.615
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Magnesium ion (24 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Acyl carrier protein, mitochondrial (10 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Complex i-9kd (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (44 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- Complex i-30kd (24 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Complex i subunit b13 (12 kDa, Protein from pig)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (3 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
Membrane arm of active state CI from Q10 dataset
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7vxs
Q-score: 0.578
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Complex i-b18 (15 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from pig)
- Complex i-b17 (15 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (5 kDa, Protein from pig)
- Respiratory complex i (Complex from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from pig)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (12 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (13 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (8 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 3 (12 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from pig)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from pig)
Matrix arm of deactive state CI from Q10 dataset
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7vxu
Q-score: 0.582
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (53 kDa, Protein from pig)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from pig)
- Magnesium ion (24 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Complex i-20kd (21 kDa, Protein from pig)
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (78 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Membrane arm of deactive state CI from Q10 dataset
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7vy1
Q-score: 0.538
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (53 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from pig)
- Complex i-kfyi (8 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from pig)
- Respiratory complex i (Complex from Sus scrofa)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from pig)
- Nadh dehydrogenase 1 beta subcomplex 6 (15 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from pig)
- Complex i-b15 (15 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from pig)
- Nd3 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (7 kDa, Protein from pig)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from pig)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from pig)
- Complex i-esss (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from pig)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from pig)
- Acyl carrier protein (17 kDa, Protein from pig)