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sample_name:"NADH dehydrogenase [ubiquinone] 1 subunit C2" AND sample_type:"complex" AND author_name:"Sazanov LA"

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EMD-17989

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CS respirasome from murine liver

Release date: April 24, 2024
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8pw5
Q-score: 0.465

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) [ Pubmed: 38575788 DOI: doi:10.1038/s41594-024-01255-0 ]

Sample:

Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6c (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Cytochrome c oxidase subunit 3 (29 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 9 (7 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
Heme-a (852 Da, Ligand)
Iron/sulfur cluster (351 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Cytochrome c oxidase subunit 8b, mitochondrial (7 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Mus musculus)
Sodium ion (22 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Heme c (618 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Mus musculus)
Sc respirasome from murine liver (1 MDa, Complex from Mus musculus)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Mus musculus)
Flavin mononucleotide (456 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Cox7a2l protein (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Mus musculus)
Tristearoylglycerol (891 Da, Ligand)
Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 2 (25 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Magnesium ion (24 Da, Ligand)
Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7b, mitochondrial (9 kDa, Protein from Mus musculus)
Protoporphyrin ix containing fe (616 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Copper (ii) ion (63 Da, Ligand)
Cytochrome b (43 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7a2, mitochondrial (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Mus musculus)
Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Dinuclear copper ion (127 Da, Ligand)
Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6a2, mitochondrial (10 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 1 (56 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (19 kDa, Protein from Mus musculus)

[Show more]

EMD-17990

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C respirasome from murine liver

Release date: April 24, 2024
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8pw6
Q-score: 0.514

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) [ Pubmed: 38575788 DOI: doi:10.1038/s41594-024-01255-0 ]

Sample:

Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6c (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Cytochrome c oxidase subunit 3 (29 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 9 (7 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
Heme-a (852 Da, Ligand)
Iron/sulfur cluster (351 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Cytochrome c oxidase subunit 8b, mitochondrial (7 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Mus musculus)
Sodium ion (22 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
C respirasome from murine liver (1 MDa, Complex from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Heme c (618 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Mus musculus)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Mus musculus)
Flavin mononucleotide (456 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Mus musculus)
Tristearoylglycerol (891 Da, Ligand)
Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 2 (25 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Magnesium ion (24 Da, Ligand)
Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7b, mitochondrial (9 kDa, Protein from Mus musculus)
Protoporphyrin ix containing fe (616 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Copper (ii) ion (63 Da, Ligand)
Cytochrome b (43 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7a2, mitochondrial (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Mus musculus)
Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Dinuclear copper ion (127 Da, Ligand)
Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6a2, mitochondrial (10 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 1 (56 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (19 kDa, Protein from Mus musculus)

[Show more]

EMD-17991

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A respirasome from murine liver

Release date: April 24, 2024
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8pw7
Q-score: 0.471

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) [ Pubmed: 38575788 DOI: doi:10.1038/s41594-024-01255-0 ]

Sample:

Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6c (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Cytochrome c oxidase subunit 3 (29 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
A respirasome from murine liver (1 MDa, Complex from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 9 (7 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
Heme-a (852 Da, Ligand)
Iron/sulfur cluster (351 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Cytochrome c oxidase subunit 8b, mitochondrial (7 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Mus musculus)
Sodium ion (22 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Heme c (618 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Mus musculus)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Mus musculus)
Flavin mononucleotide (456 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Mus musculus)
Tristearoylglycerol (891 Da, Ligand)
Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 2 (25 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Magnesium ion (24 Da, Ligand)
Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7b, mitochondrial (9 kDa, Protein from Mus musculus)
Protoporphyrin ix containing fe (616 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Copper (ii) ion (63 Da, Ligand)
Cytochrome b (43 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 7a2, mitochondrial (9 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Mus musculus)
Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Dinuclear copper ion (127 Da, Ligand)
Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Mus musculus)
Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 6a2, mitochondrial (10 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 1 (56 kDa, Protein from Mus musculus)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (19 kDa, Protein from Mus musculus)

[Show more]

EMD-19145

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Closed Complex I from murine brain

Release date: April 24, 2024
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8rgp
Q-score: 0.545

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) [ Pubmed: 38575788 DOI: doi:10.1038/s41594-024-01255-0 ]

Sample:

Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Closed complex i from murine brain (1 MDa, Complex from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
Iron/sulfur cluster (351 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Flavin mononucleotide (456 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)

[Show more]

EMD-19146

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Open Complex I from murine liver

Release date: April 24, 2024
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8rgq
Q-score: 0.515

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) [ Pubmed: 38575788 DOI: doi:10.1038/s41594-024-01255-0 ]

Sample:

Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Open complex i from murine liver (1 MDa, Complex from Mus musculus)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
Iron/sulfur cluster (351 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Flavin mononucleotide (456 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)

[Show more]

EMD-19147

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Closed Complex I from murine liver

Release date: April 24, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8rgr
Q-score: 0.545

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) [ Pubmed: 38575788 DOI: doi:10.1038/s41594-024-01255-0 ]

Sample:

Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Closed complex i from murine liver (1 MDa, Complex from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
Iron/sulfur cluster (351 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Flavin mononucleotide (456 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)

[Show more]

EMD-19148

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Open Complex I from murine brain

Release date: April 24, 2024
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8rgt
Q-score: 0.526

Vercellino I, Sazanov LA

Nat Struct Mol Biol (2024) [ Pubmed: 38575788 DOI: doi:10.1038/s41594-024-01255-0 ]

Sample:

Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Mus musculus)
Cardiolipin (1 kDa, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Mus musculus)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Mus musculus)
2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Mus musculus)
Potassium ion (39 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from Mus musculus)
Zinc ion (65 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Mus musculus)
Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Mus musculus)
Acyl carrier protein, mitochondrial (17 kDa, Protein from Mus musculus)
Magnesium ion (24 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from Mus musculus)
Iron/sulfur cluster (351 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Open complex i from murine brain (1 MDa, Complex from Mus musculus)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Mus musculus)
1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Mus musculus)
Flavin mononucleotide (456 Da, Ligand)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from Mus musculus)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Mus musculus)

[Show more]

EMD-11247

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Complex I during turnover, open3

Release date: Oct. 14, 2020
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6zkf
Q-score: 0.564

Kampjut D, Sazanov LA

Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]

Sample:

Nadh:ubiquinone oxidoreductase core subunit s1 (79 kDa, Protein from Sheep)
Adenosine monophosphate (347 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
Cardiolipin (1 kDa, Ligand)
Acyl carrier protein (17 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from Sheep)
Mitochondrial complex i, esss subunit (17 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from Sheep)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Mitochondrial complex i, b13 subunit (13 kDa, Protein from Sheep)
Mitochondrial complex i, tyky subunit (24 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit a6 (16 kDa, Protein from Sheep)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
Mitochondrial complex i, 24 kda subunit (27 kDa, Protein from Sheep)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
Mitochondrial complex i, pdsw subunit (20 kDa, Protein from Sheep)
Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sheep)
Flavin mononucleotide (456 Da, Ligand)
Mitochondrial complex i, 49 kda subunit (52 kDa, Protein from Sheep)
Potassium ion (39 Da, Ligand)
Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
Zinc ion (65 Da, Ligand)
Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)
Mitochondrial complex i, psst subunit (24 kDa, Protein from Sheep)
2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione (322 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
Mitochondrial complex i, b14.7 subunit (14 kDa, Protein from Sheep)
Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase core subunit s3 (30 kDa, Protein from Sheep)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
Mitochondrial complex i, 13 kda subunit (13 kDa, Protein from Sheep)
Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sheep)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit b5 (21 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit b2 (12 kDa, Protein from Sheep)
Mitochondrial complex i, kfyi subunit (8 kDa, Protein from Sheep)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sheep)
Mitochondrial complex i, b17 subunit (15 kDa, Protein from Sheep)
Mitochondrial complex i, mwfe subunit (8 kDa, Protein from Sheep)
Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sheep)
Mitochondrial complex i, mnll subunit (7 kDa, Protein from Sheep)
Complex i during turnover, open3 (1 MDa, Complex from Ovis aries)
Myristic acid (228 Da, Ligand)
Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from Sheep)
Mitochondrial complex i, 10 kda subunit (11 kDa, Protein from Sheep)
Iron/sulfur cluster (351 Da, Ligand)

[Show more]

EMD-11242

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Membrane domain of open complex I during turnover

Release date: Oct. 7, 2020
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 6zka
Q-score: 0.643

Kampjut D, Sazanov LA

Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]

Sample:

Adenosine monophosphate (347 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
Cardiolipin (1 kDa, Ligand)
Acyl carrier protein (17 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from Sheep)
Mitochondrial complex i, esss subunit (17 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
Membrane domain of open complex i during turnover (1 MDa, Complex from Ovis aries)
Mitochondrial complex i, pdsw subunit (20 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
Mitochondrial complex i, b14.7 subunit (14 kDa, Protein from Sheep)
Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
Water (18 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit b5 (21 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit b2 (12 kDa, Protein from Sheep)
Mitochondrial complex i, kfyi subunit (8 kDa, Protein from Sheep)
Mitochondrial complex i, b17 subunit (15 kDa, Protein from Sheep)
Mitochondrial complex i, mwfe subunit (8 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
Mitochondrial complex i, mnll subunit (7 kDa, Protein from Sheep)
2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione (322 Da, Ligand from Sheep)
Myristic acid (228 Da, Ligand)
Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)
Mitochondrial complex i, nd4l subunit (52 kDa, Protein from Sheep)

[Show more]

EMD-11243

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Membrane domain of closed complex I during turnover

Release date: Oct. 7, 2020
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6zkb
Q-score: 0.551

Kampjut D, Sazanov LA

Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]

Sample:

Adenosine monophosphate (347 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
Cardiolipin (1 kDa, Ligand)
Acyl carrier protein (17 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from Sheep)
Mitochondrial complex i, esss subunit (17 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
Mitochondrial complex i, pdsw subunit (20 kDa, Protein from Sheep)
Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
Mitochondrial complex i, b14.7 subunit (14 kDa, Protein from Sheep)
Mitochondrial complex i, 49 kda subunit (52 kDa, Protein from Sheep)
Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
Water (18 Da, Ligand)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit b5 (21 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit b2 (12 kDa, Protein from Sheep)
Mitochondrial complex i, kfyi subunit (8 kDa, Protein from Sheep)
Mitochondrial complex i, b17 subunit (15 kDa, Protein from Sheep)
Mitochondrial complex i, mwfe subunit (8 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
Mitochondrial complex i, mnll subunit (7 kDa, Protein from Sheep)
Membrane domain of closed complex i during turnover (1 MDa, Complex from Ovis aries)
Myristic acid (228 Da, Ligand)
Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from Sheep)
Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)

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