Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"Human GABA-A receptor alpha1-beta2-gamma2 subtype in complex with GABA and dehydroepiandrosterone sulfate" AND database:"EMDB"

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EMD-40506

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Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus dehydroepiandrosterone sulfate

Release date: Aug. 30, 2023
Resolution: 2.71 Å
EM Method: Single-particle
Fitted PDBs: 8sid
Q-score: 0.539

Legesse DH, Fan C, Teng J, Zhuang Y, Howard RJ, Noviello CM, Lindahl E, Hibbs RE

Nat Commun (2023) 14 pp. 5091-5091 [ DOI: doi:10.1038/s41467-023-40800-1 Pubmed: 37607940 ]

Sample:

2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Igg2b fab heavy chain (49 kDa, Protein from Mus musculus)
Gamma-aminobutyric acid receptor subunit gamma-2 (47 kDa, Protein from Homo sapiens)
Phosphatidylethanolamine (734 Da, Ligand)
Kappa fab light chain (23 kDa, Protein from Mus musculus)
Gamma-amino-butanoic acid (103 Da, Ligand)
17-oxoandrost-5-en-3beta-yl hydrogen sulfate (368 Da, Ligand)
Gamma-aminobutyric acid receptor subunit alpha-1 (41 kDa, Protein from Homo sapiens)
Human gaba-a receptor alpha1-beta2-gamma2 subtype in complex with gaba and dehydroepiandrosterone sulfate (Complex from Homo sapiens)
O-[(r)-[(2s)-2-(hexadecanoyloxy)-3-(octadecanoyloxy)propoxy](hydroxy)phosphoryl]-d-serine (764 Da, Ligand)
Gamma-aminobutyric acid receptor subunit beta-2 (41 kDa, Protein from Homo sapiens)
(2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)

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