HACE1 in complex with RAC1 Q61L
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8q0n
Q-score: 0.277
During J, Wolter M, Toplak JJ, Torres C, Dybkov O, Fokkens TJ, Bohnsack KE, Urlaub H, Steinchen W, Dienemann C, Lorenz S
Nat Struct Mol Biol (2024) 31 pp. 364-377 [ Pubmed: 38332367 DOI: doi:10.1038/s41594-023-01203-4 ]
- E3 ubiquitin-protein ligase hace1 (99 kDa, Protein from Homo sapiens)
- Hace1 in complex with rac1 q61l (Complex from Homo sapiens)
- Ras-related c3 botulinum toxin substrate 1 (23 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Iodoacetic acid (185 Da, Ligand)
Human spliceosomal PM5 C* complex
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8c6j
Q-score: 0.353
Dybkov O, Preussner M, El Ayoubi L, Feng VY, Harnisch C, Merz K, Leupold P, Yudichev P, Agafonov DE, Will CL, Girard C, Dienemann C, Urlaub H, Kastner B, Heyd F, Luehrmann R
Sci Adv (2023) 9 pp. eadf1785- [ DOI: doi:10.1126/sciadv.adf1785 Pubmed: 36867703 ]
- Peptidyl-prolyl cis-trans isomerase-like 3 (18 kDa, Protein from human)
- U5 snrna (36 kDa, RNA from human)
- Crooked neck-like protein 1 (83 kDa, Protein from human)
- Small nuclear ribonucleoprotein g (8 kDa, Protein from human)
- Small nuclear ribonucleoprotein sm d1 (13 kDa, Protein from human)
- Rna-binding protein 8a (19 kDa, Protein from human)
- Pre-mrna-splicing factor isy1 homolog (33 kDa, Protein from human)
- Pre-mrna-processing factor 17 (65 kDa, Protein from human)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Intron-binding protein aquarius (171 kDa, Protein from human)
- Pre-mrna-processing factor 19 (55 kDa, Protein from human)
- Protein mago nashi homolog (17 kDa, Protein from human)
- Small nuclear ribonucleoprotein f (9 kDa, Protein from human)
- Inositol hexakisphosphate (660 Da, Ligand)
- U6 snrna (34 kDa, RNA from human)
- U5 small nuclear ribonucleoprotein 200 kda helicase (244 kDa, Protein from human)
- Nitric oxide synthase-interacting protein (33 kDa, Protein from human)
- Pm5 5' exon (78 kDa, RNA from Homo sapiens)
- Small nuclear ribonucleoprotein sm d2 (13 kDa, Protein from human)
- Pleiotropic regulator 1 (57 kDa, Protein from human)
- Peptidyl-prolyl cis-trans isomerase-like 1 (18 kDa, Protein from human)
- U2 snrna (60 kDa, RNA from human)
- Small nuclear ribonucleoprotein sm d3 (13 kDa, Protein from human)
- Potassium ion (39 Da, Ligand)
- Pre-mrna-splicing factor cwc22 homolog (57 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- Atp-dependent rna helicase dhx8 (139 kDa, Protein from human)
- Splicing factor cactin (88 kDa, Protein from human)
- Splicing regulator sde2 (49 kDa, Protein from human)
- Pre-mrna-splicing factor slu7 (68 kDa, Protein from human)
- U2 small nuclear ribonucleoprotein b'' (25 kDa, Protein from human)
- Cell division cycle 5-like protein (92 kDa, Protein from human)
- Prkr-interacting protein 1 (21 kDa, Protein from human)
- Pre-mrna-splicing factor spf27 (26 kDa, Protein from human)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Human spliceosomal c* complex assembled on pm5 pre-mrna (Complex from Homo sapiens)
- Spliceosome-associated protein cwc15 homolog (26 kDa, Protein from human)
- Sting er exit protein (25 kDa, Protein from human)
- Protein fam32a (13 kDa, Protein from human)
- Pre-mrna-splicing factor rbm22 (46 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)
- U5 small nuclear ribonucleoprotein 40 kda protein (39 kDa, Protein from human)
- Small nuclear ribonucleoprotein e (10 kDa, Protein from human)
- Probable atp-dependent rna helicase ddx41 (69 kDa, Protein from human)
- Pre-mrna-splicing factor syf1 (100 kDa, Protein from human)
- 116 kda u5 small nuclear ribonucleoprotein component (109 kDa, Protein from human)
- Snw domain-containing protein 1 (61 kDa, Protein from human)
- Protein bud31 homolog (17 kDa, Protein from human)
- Nf-kappa-b-activating protein (47 kDa, Protein from human)
- Peptidyl-prolyl cis-trans isomerase e (33 kDa, Protein from human)
- U2 small nuclear ribonucleoprotein a' (28 kDa, Protein from human)
- Small nuclear ribonucleoprotein-associated proteins b and b' (24 kDa, Protein from human)
- Eukaryotic initiation factor 4a-iii (46 kDa, Protein from human)
- Splicing factor c9orf78 (33 kDa, Protein from human)
- Protein fam50a (40 kDa, Protein from human)
- Pm5 intron (74 kDa, RNA from Homo sapiens)
- Pre-mrna-splicing factor syf2 (28 kDa, Protein from human)
- Serine/arginine repetitive matrix protein 2 (300 kDa, Protein from human)
- Pre-mrna-processing-splicing factor 8 (273 kDa, Protein from human)
- Splicing factor ess-2 homolog (52 kDa, Protein from human)
Structural organization of a late activated human spliceosome (Baqr, core region)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7qtt
Q-score: 0.384
Schmitzova J, Cretu C, Dienemann C, Urlaub H, Pena V
Nature (2023) 617 pp. 842-850 [ DOI: doi:10.1038/s41586-023-06049-w Pubmed: 37165190 ]
- Putative pre-mrna-splicing factor atp-dependent rna helicase dhx16 (119 kDa, Protein from human)
- Pre-mrna-splicing factor cwc22 homolog (105 kDa, Protein from human)
- U2snrna (60 kDa, RNA from human)
- Crooked neck-like protein 1 (100 kDa, Protein from human)
- Small nuclear ribonucleoprotein g (8 kDa, Protein from human)
- Small nuclear ribonucleoprotein sm d1 (13 kDa, Protein from human)
- Phd finger-like domain-containing protein 5a (12 kDa, Protein from human)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Inositol hexakisphosphate (660 Da, Ligand)
- Small nuclear ribonucleoprotein f (9 kDa, Protein from human)
- Small nuclear ribonucleoprotein sm d2 (13 kDa, Protein from human)
- Pleiotropic regulator 1 (57 kDa, Protein from human)
- Snw domain-containing protein 1 (61 kDa, Protein from human)
- Peptidyl-prolyl cis-trans isomerase-like 1 (18 kDa, Protein from human)
- Late human activated spliceosome arrested with a dominant-negative mutant of the splicing helicase aquarius (aquarius k829a) (Complex from Homo sapiens)
- Small nuclear ribonucleoprotein sm d3 (13 kDa, Protein from human)
- Splicing factor 3a subunit 2 (49 kDa, Protein from human)
- Splicing factor 3b subunit 1 (146 kDa, Protein from human)
- Bud13 homolog (70 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- Ring-type e3 ubiquitin-protein ligase ppil2 (58 kDa, Protein from human)
- G-patch domain and kow motifs-containing protein (52 kDa, Protein from human)
- Peptidyl-prolyl cis-trans isomerase-like 4 (57 kDa, Protein from human)
- Cell division cycle 5-like protein (92 kDa, Protein from human)
- Splicing factor 3b subunit 2 (100 kDa, Protein from human)
- Minx (102 kDa, RNA from unidentified adenovirus)
- Splicing factor 3b subunit 3 (135 kDa, Protein from human)
- U6snrna (34 kDa, RNA from Homo sapiens)
- Spliceosome-associated protein cwc15 homolog (26 kDa, Protein from human)
- Pre-mrna-splicing factor rbm22 (46 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)
- Splicing factor 3b subunit 4 (44 kDa, Protein from human)
- Small nuclear ribonucleoprotein e (10 kDa, Protein from human)
- 116 kda u5 small nuclear ribonucleoprotein component (109 kDa, Protein from human)
- Protein bud31 homolog (17 kDa, Protein from human)
- Ring finger protein 113a (38 kDa, Protein from human)
- Small nuclear ribonucleoprotein-associated proteins b and b' (24 kDa, Protein from human)
- Splicing factor 3b subunit 5 (10 kDa, Protein from human)
- Splicing factor 3a subunit 3 (58 kDa, Protein from human)
- Serine/arginine repetitive matrix protein 2 (300 kDa, Protein from human)
- Pre-mrna-processing-splicing factor 8 (273 kDa, Protein from human)
- U5 snrna (37 kDa, RNA from human)
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 8ch6
Q-score: 0.154
Schmitzova J, Cretu C, Dienemann C, Urlaub H, Pena V
Nature (2023) 617 pp. 842-850 [ DOI: doi:10.1038/s41586-023-06049-w Pubmed: 37165190 ]
- Putative pre-mrna-splicing factor atp-dependent rna helicase dhx16 (119 kDa, Protein from human)
- Pre-mrna-splicing factor cwc22 homolog (105 kDa, Protein from human)
- Crooked neck-like protein 1 (100 kDa, Protein from human)
- Small nuclear ribonucleoprotein g (8 kDa, Protein from human)
- Small nuclear ribonucleoprotein sm d1 (13 kDa, Protein from human)
- Phd finger-like domain-containing protein 5a (12 kDa, Protein from human)
- Pre-mrna-splicing factor isy1 homolog (33 kDa, Protein from human)
- Pre-mrna-processing factor 17 (65 kDa, Protein from human)
- Intron-binding protein aquarius (171 kDa, Protein from human)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Pre-mrna-processing factor 19 (55 kDa, Protein from human)
- Inositol hexakisphosphate (660 Da, Ligand)
- Small nuclear ribonucleoprotein f (9 kDa, Protein from human)
- U5 small nuclear ribonucleoprotein 200 kda helicase (244 kDa, Protein from human)
- Splicing factor 3a subunit 1 (88 kDa, Protein from human)
- Small nuclear ribonucleoprotein sm d2 (13 kDa, Protein from human)
- Pleiotropic regulator 1 (57 kDa, Protein from human)
- Snw domain-containing protein 1 (61 kDa, Protein from human)
- Rnu2-1 (60 kDa, RNA from human)
- Small nuclear ribonucleoprotein sm d3 (13 kDa, Protein from human)
- Late human activated spliceosome arrested with a dominant-negative mutant of the splicing helicase aquarius (aquarius k829a) (Complex from Homo sapiens)
- Rnu6-1 (34 kDa, RNA from Homo sapiens)
- Peptidyl-prolyl cis-trans isomerase-like 1 (18 kDa, Protein from human)
- Splicing factor 3a subunit 2 (49 kDa, Protein from human)
- Splicing factor 3b subunit 1 (146 kDa, Protein from human)
- Bud13 homolog (70 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- Minx-m3 (102 kDa, RNA from unidentified adenovirus)
- Ring-type e3 ubiquitin-protein ligase ppil2 (58 kDa, Protein from human)
- G-patch domain and kow motifs-containing protein (52 kDa, Protein from human)
- Peptidyl-prolyl cis-trans isomerase-like 4 (57 kDa, Protein from human)
- Pre-mrna-splicing factor spf27 (26 kDa, Protein from human)
- Cell division cycle 5-like protein (92 kDa, Protein from human)
- Splicing factor 3b subunit 2 (100 kDa, Protein from human)
- U2 small nuclear ribonucleoprotein b'' (25 kDa, Protein from human)
- Splicing factor 3b subunit 3 (135 kDa, Protein from human)
- Spliceosome-associated protein cwc15 homolog (26 kDa, Protein from human)
- Rnu5a-1 (37 kDa, RNA from human)
- Pre-mrna-splicing factor rbm22 (46 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)
- U5 small nuclear ribonucleoprotein 40 kda protein (39 kDa, Protein from human)
- Splicing factor 3b subunit 4 (44 kDa, Protein from human)
- Small nuclear ribonucleoprotein e (10 kDa, Protein from human)
- Pre-mrna-splicing factor syf1 (100 kDa, Protein from human)
- 116 kda u5 small nuclear ribonucleoprotein component (109 kDa, Protein from human)
- Protein bud31 homolog (17 kDa, Protein from human)
- Peptidyl-prolyl cis-trans isomerase e (33 kDa, Protein from human)
- Ring finger protein 113a (38 kDa, Protein from human)
- U2 small nuclear ribonucleoprotein a' (28 kDa, Protein from human)
- Small nuclear ribonucleoprotein-associated proteins b and b' (24 kDa, Protein from human)
- Splicing factor 3b subunit 5 (10 kDa, Protein from human)
- Splicing factor 3a subunit 3 (58 kDa, Protein from human)
- Serine/arginine repetitive matrix protein 2 (300 kDa, Protein from human)
- Pre-mrna-processing-splicing factor 8 (273 kDa, Protein from human)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7of4
Q-score: 0.534
Hillen HS, Lavdovskaia E, Nadler F, Hanitsch E, Linden A, Bohnsack KE, Urlaub H, Richter-Dennerlein R
Nat Commun (2021) 12 pp. 3672-3672 [ Pubmed: 34135319 DOI: doi:10.1038/s41467-021-23702-y ]
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Human)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Human)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Human)
- Putative gtp-binding protein 6 (Complex from Homo sapiens)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Human)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Human)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Human)
- Mature human mitochondrial ribosome large subunit in complex with gtpbp6 (ptc conformation 1). (Complex)
- Mature human mitochondrial ribosome large subunit (Complex from Homo sapiens)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Human)
- Putative gtp-binding protein 6 (56 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l36, mitochondrial (11 kDa, Protein from Human)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Human)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Human)
- Mitochondrial trnaval (22 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Human)
- 39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Human)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Human)
- 39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Human)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Human)
- 39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Human)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Human)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Human)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Human)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Human)
- 16s ribosomal rna (500 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Human)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Human)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Human)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Human)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Human)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7of5
Q-score: 0.501
Hillen HS, Lavdovskaia E, Nadler F, Hanitsch E, Linden A, Bohnsack KE, Urlaub H, Richter-Dennerlein R
Nat Commun (2021) 12 pp. 3672-3672 [ Pubmed: 34135319 DOI: doi:10.1038/s41467-021-23702-y ]
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Human)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Human)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Human)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Human)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Human)
- 5-methylcytosine rrna methyltransferase nsun4 (43 kDa, Protein from Human)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Human)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Human)
- 39s ribosomal protein l36, mitochondrial (11 kDa, Protein from Human)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Human)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Human)
- 39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Human)
- Mief1 upstream open reading frame protein (8 kDa, Protein from Human)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Human)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Human)
- 39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Human)
- Mitochondrial trnaval (22 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Human)
- 39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Human)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Human)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from Human)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Human)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Human)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Human)
- 16s ribosomal rna (500 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Human)
- Mitochondrial ribosome-associated gtpase 2 (44 kDa, Protein from Human)
- Human mitochondrial ribosome large subunit assembly intermediate in complex with mterf4-nsun4 and gtpbp5 (dataset2). (Complex from Homo sapiens)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Human)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Human)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Human)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Human)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Human)
- Transcription termination factor 4, mitochondrial (44 kDa, Protein from Human)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Human)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7of6
Q-score: 0.543
Hillen HS, Lavdovskaia E, Nadler F, Hanitsch E, Linden A, Bohnsack KE, Urlaub H, Richter-Dennerlein R
Nat Commun (2021) 12 pp. 3672-3672 [ Pubmed: 34135319 DOI: doi:10.1038/s41467-021-23702-y ]
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Human)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Human)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Human)
- Mature human mitochondrial ribosome large subunit in complex with gtpbp6 (ptc conformation 2). (Complex from Homo sapiens)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Human)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Human)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Human)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Human)
- 39s ribosomal protein l36, mitochondrial (11 kDa, Protein from Human)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Human)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Human)
- 39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Human)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Human)
- 39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Human)
- Mitochondrial trnaval (22 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Human)
- 39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Human)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Human)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Human)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Human)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Human)
- 16s ribosomal rna (500 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Human)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Human)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Human)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Human)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Human)
- Putative gtp-binding protein 6 (56 kDa, Protein from Human)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Human)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7of2
Q-score: 0.537
Hillen HS, Lavdovskaia E, Nadler F, Hanitsch E, Linden A, Bohnsack KE, Urlaub H, Richter-Dennerlein R
Nat Commun (2021) 12 pp. 3672-3672 [ Pubmed: 34135319 DOI: doi:10.1038/s41467-021-23702-y ]
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Human)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Human)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Human)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Human)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Human)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Human)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Human)
- Putative gtp-binding protein 6 (56 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l36, mitochondrial (11 kDa, Protein from Human)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Human)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Human)
- Mitochondrial trnaval (22 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Human)
- 39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Human)
- Mief1 upstream open reading frame protein (8 kDa, Protein from Human)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Human)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Human)
- Human mitochondrial ribosome large subunit assembly intermediate in complex with gtpbp6. (Complex from Homo sapiens)
- 39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Human)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Human)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Human)
- 39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Human)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Human)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from Human)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Human)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Human)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Human)
- 16s ribosomal rna (500 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Human)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Human)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Human)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Human)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Human)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7of3
Q-score: 0.527
Hillen HS, Lavdovskaia E, Nadler F, Hanitsch E, Linden A, Bohnsack KE, Urlaub H, Richter-Dennerlein R
Nat Commun (2021) 12 pp. 3672-3672 [ Pubmed: 34135319 DOI: doi:10.1038/s41467-021-23702-y ]
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Human)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Human)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Human)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Human)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Human)
- 5-methylcytosine rrna methyltransferase nsun4 (43 kDa, Protein from Human)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Human)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Human)
- 39s ribosomal protein l36, mitochondrial (11 kDa, Protein from Human)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Human)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Human)
- 16s ribosomal rna (500 kDa, RNA from Human)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Human)
- 39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Human)
- Mief1 upstream open reading frame protein (8 kDa, Protein from Human)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Human)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Human)
- 39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Human)
- Mitochondrial trnaval (22 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Human)
- 39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Human)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Human)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from Human)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Human)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Human)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Human)
- Human mitochondrial ribosome large subunit assembly intermediate in complex with mterf4-nsun4 (dataset2). (Complex from Homo sapiens)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Human)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Human)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Human)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Human)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Human)
- Transcription termination factor 4, mitochondrial (44 kDa, Protein from Human)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Human)
Resolution: 8.0 Å
EM Method: Single-particle
Fitted PDBs: 7abi
Q-score: 0.152
Townsend C, Leelaram MN, Agafonov DE, Dybkov O, Will CL, Bertram K, Urlaub H, Kastner B, Stark H, Luhrmann R
Science (2020) 370 [ DOI: doi:10.1126/science.abc3753 Pubmed: 33243851 ]
- Inositol hexakisphosphate (660 Da, Ligand)
- U2 snrna (60 kDa, RNA from Human)
- U2 small nuclear ribonucleoprotein b'' (25 kDa, Protein from Human)
- Spliceosome-associated protein cwc15 homolog (26 kDa, Protein from Human)
- Human pre-bact-2 spliceosome (Complex)
- Crooked neck-like protein 1 (100 kDa, Protein from Human)
- U5 small nuclear ribonucleoprotein 40 kda protein (39 kDa, Protein from Human)
- Smad nuclear-interacting protein 1 (45 kDa, Protein from Human)
- U5 snrna (36 kDa, RNA from Human)
- Rna-binding motif protein, x-linked 2 (37 kDa, Protein from Human)
- Pre-mrna-processing factor 17 (65 kDa, Protein from Human)
- Bud13 homolog (70 kDa, Protein from Human)
- 116 kda u5 small nuclear ribonucleoprotein component (109 kDa, Protein from Human)
- Dna/rna-binding protein kin17 (45 kDa, Protein from Human)
- U2 small nuclear ribonucleoprotein a' (28 kDa, Protein from Human)
- Small nuclear ribonucleoprotein-associated proteins b and b' (24 kDa, Protein from Human)
- Splicing factor 3b subunit 2 (100 kDa, Protein from Human)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Small nuclear ribonucleoprotein sm d1 (13 kDa, Protein from Human)
- U5 small nuclear ribonucleoprotein 200 kda helicase (244 kDa, Protein from Human)
- Splicing factor 3b subunit 1 (146 kDa, Protein from Human)
- Splicing factor 3b subunit 6 (14 kDa, Protein from Human)
- Splicing factor 3b subunit 3 (135 kDa, Protein from Human)
- Splicing factor 3a subunit 1 (88 kDa, Protein from Human)
- Pleiotropic regulator 1 (57 kDa, Protein from Human)
- Splicing factor 3b subunit 5 (10 kDa, Protein from Human)
- Splicing factor 3a subunit 2 (49 kDa, Protein from Human)
- Intron-binding protein aquarius (171 kDa, Protein from Human)
- Ubiquitin-like protein 5 (8 kDa, Protein from Human)
- Minx m3 pre-mrna (103 kDa, RNA from synthetic construct)
- Human pre-bact-2 spliceosome (Complex from Homo sapiens)
- Beta-catenin-like protein 1 (65 kDa, Protein from Human)
- Zinc finger matrin-type protein 2 (23 kDa, Protein from Human)
- Peptidyl-prolyl cis-trans isomerase e (33 kDa, Protein from Human)
- Cell division cycle 5-like protein (92 kDa, Protein from Human)
- Small nuclear ribonucleoprotein f (9 kDa, Protein from Human)
- Snw domain-containing protein 1 (61 kDa, Protein from Human)
- Small nuclear ribonucleoprotein sm d2 (13 kDa, Protein from Human)
- Microfibrillar-associated protein 1 (52 kDa, Protein from Human)
- Protein bud31 homolog (17 kDa, Protein from Human)
- Small nuclear ribonucleoprotein sm d3 (13 kDa, Protein from Human)
- Small nuclear ribonucleoprotein e (10 kDa, Protein from Human)
- Small nuclear ribonucleoprotein g (8 kDa, Protein from Human)
- Splicing factor 3b subunit 4 (44 kDa, Protein from Human)
- Pre-mrna-splicing factor rbm22 (46 kDa, Protein from Human)
- Magnesium ion (24 Da, Ligand)
- Pre-mrna-splicing factor 38a (37 kDa, Protein from Human)
- Pre-mrna-splicing factor syf1 (100 kDa, Protein from Human)
- Splicing factor 3a subunit 3 (58 kDa, Protein from Human)
- Pre-mrna-processing-splicing factor 8 (273 kDa, Protein from Human)
- Minx m3 pre-mrna (Complex from synthetic construct)
- Phd finger-like domain-containing protein 5a (12 kDa, Protein from Human)
- Ring-type e3 ubiquitin-protein ligase ppil2 (58 kDa, Protein from Human)
- U6 snrna (34 kDa, RNA from Human)
- Serine/arginine repetitive matrix protein 1 (102 kDa, Protein from Human)