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MAP7 MTBD (microtubule binding domain) decorated microtubule protofilament
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8rc1
Q-score: 0.462
Adler A, Bangera M, Beugelink JW, Bahri S, van Ingen H, Moores CA, Baldus M
Nat Commun (2024) 15 pp. 1948-1948 [ Pubmed: 38431715 DOI: doi:10.1038/s41467-024-46260-5 ]
- Complex of map7 mtbd (microtubule binding domain) with 14pf microtubule (13 MDa, Complex from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (48 kDa, Protein from Sus scrofa)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Microtubule associated protein 7 (map7) (7 kDa, Protein from Homo sapiens)
P. berghei kinesin-8B motor domain in AMPPNP state bound to tubulin dimer
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7z2b
Q-score: 0.367
Liu T, Shilliday F, Cook AD, Zeeshan M, Brady D, Tewari R, Sutherland CJ, Roberts AJ, Moores CA
Nat Commun (2022) 13 pp. 6988-6988 [ DOI: doi:10.1038/s41467-022-34710-x Pubmed: 36384964 ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (47 kDa, Protein from pig)
- Detyrosinated tubulin alpha-1b chain (47 kDa, Protein from pig)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- P. berghei kinesin-8b motor domain in amppnp state bound to tubulin dimer (Complex from Plasmodium berghei)
- Kinesin-8, putative (38 kDa, Protein from Plasmodium berghei)
- Magnesium ion (24 Da, Ligand)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
P. berghei kinesin-8B motor domain in no nucleotide state bound to tubulin dimer
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7z2a
Q-score: 0.253
Liu T, Shilliday F, Cook AD, Zeeshan M, Brady D, Tewari R, Sutherland CJ, Roberts AJ, Moores CA
Nat Commun (2022) 13 pp. 6988-6988 [ DOI: doi:10.1038/s41467-022-34710-x Pubmed: 36384964 ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (47 kDa, Protein from pig)
- Detyrosinated tubulin alpha-1b chain (47 kDa, Protein from Pig)
- P. berghei kinesin-8b motor domain in no nucleotide state bound to tubulin dimer (Complex from Plasmodium berghei)
- Magnesium ion (24 Da, Ligand)
- Kinesin-8, putative (39 kDa, Protein from Plasmodium berghei)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
P. falciparum kinesin-8B motor domain in no nucleotide bound to tubulin dimer
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7z2c
Q-score: 0.296
Liu T, Shilliday F, Cook AD, Zeeshan M, Brady D, Tewari R, Sutherland CJ, Roberts AJ, Moores CA
Nat Commun (2022) 13 pp. 6988-6988 [ DOI: doi:10.1038/s41467-022-34710-x Pubmed: 36384964 ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin beta chain (47 kDa, Protein from pig)
- Detyrosinated tubulin alpha-1b chain (47 kDa, Protein from pig)
- Magnesium ion (24 Da, Ligand)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Kinesin-like protein (39 kDa, Protein from Plasmodium falciparum)
- P. falciparum kinesin-8b motor domain in no nucleotide state bound to tubulin dimer (Complex from Plasmodium berghei)
Resolution: 4.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 7nb8
Q-score: 0.268
Cook AD, Roberts AJ, Atherton J, Tewari R, Topf M, Moores CA
J Biol Chem (2021) 297 pp. 101063-101063 [ DOI: doi:10.1016/j.jbc.2021.101063 Pubmed: 34375637 ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 14 protofilament microtubule of alpha/beta-tubulin dimers, with kinesin-5 motor domain bound 1:1 to tubulin dimers. (Complex)
- Tubulin alpha-1b chain (50 kDa, Protein from Pig)
- Alpha/beta-tubulin (Complex from Sus scrofa)
- Kinesin-5 (46 kDa, Protein from Plasmodium falciparum (isolate 3D7))
- Kinesin-5 (Complex from Plasmodium falciparum (isolate 3D7))
- Magnesium ion (24 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Pig)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
Resolution: 4.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 7nba
Q-score: 0.268
Cook AD, Roberts AJ, Atherton J, Tewari R, Topf M, Moores CA
J Biol Chem (2021) 297 pp. 101063-101063 [ DOI: doi:10.1016/j.jbc.2021.101063 Pubmed: 34375637 ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Kinesin motor domain-containing protein,kinesin motor domain-containing protein (46 kDa, Protein from Plasmodium falciparum (isolate NF54))
- Tubulin alpha-1b chain (50 kDa, Protein from Pig)
- 14 protofilament microtubule complexed with plasmodium falciparum kinesin-5 motor domain bound to amppnp. asymmetric unit. (Complex from Plasmodium falciparum (isolate NF54))
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Pig)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
Microtubule complexed with Kif15 motor domain. Symmetrised asymmetric unit
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 6zpi
Q-score: 0.238
Atherton J, Hummel JJ, Olieric N, Locke J, Pena A, Rosenfeld SS, Steinmetz MO, Hoogenraad CC, Moores CA
eLife (2020) 9 [ Pubmed: 33252036 DOI: doi:10.7554/eLife.61481 ]
- Tubulin alpha-1b chain (48 kDa, Protein from Pig)
- Taxol (853 Da, Ligand)
- Microtubule (Complex from Sus scrofa)
- Tubulin beta chain (48 kDa, Protein from Pig)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Kif15 motor domain (amppnp bound) complexed with microtubule. symmetrised asymmetric unit. (72 kDa, Complex)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Kinesin-like protein kif15 (41 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Kif15 motor domain (Complex from Homo sapiens)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6rev
Q-score: 0.47
EMBO Rep (2020) 21 pp. e51534-e51534 [ Pubmed: 33051979 DOI: doi:10.15252/embr.202051534 ]
- Human doublecortin (Complex from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Tubulin beta-2b chain (48 kDa, Protein from Bos taurus)
- Neuronal migration protein doublecortin (11 kDa, Protein from Homo sapiens)
- Tubulin (Complex from Bos taurus)
- 5-component complex of n-terminal dc domain of human doublecortin bound to 13-protofilament gdp-microtubule lattice site composed of 4 tubulin subunits (two alpha-subunit and two beta-subunits) (Complex)
- Tubulin alpha-1b chain (48 kDa, Protein from Bos taurus)
- Magnesium ion (24 Da, Ligand)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6rf2
Q-score: 0.373
EMBO Rep (2020) 21 pp. e51534-e51534 [ Pubmed: 33051979 DOI: doi:10.15252/embr.202051534 ]
- Human doublecortin (Complex from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Neuronal migration protein doublecortin (9 kDa, Protein from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Tubulin beta-2b chain (48 kDa, Protein from Bos taurus)
- 5-component complex of c-terminal dc domain of human doublecortin bound to 13-protofilament gdp.pi-microtubule lattice site composed of 4 tubulin subunits (two alpha-subunits and two beta-subunits) (Complex)
- Tubulin (Complex from Bos taurus)
- Tubulin alpha-1b chain (48 kDa, Protein from Bos taurus)
- Magnesium ion (24 Da, Ligand)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6rfd
Q-score: 0.437
EMBO Rep (2020) 21 pp. e51534-e51534 [ Pubmed: 33051979 DOI: doi:10.15252/embr.202051534 ]
- Human doublecortin (Complex from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Tubulin beta-2b chain (48 kDa, Protein from Bos taurus)
- Neuronal migration protein doublecortin (11 kDa, Protein from Homo sapiens)
- 5-component complex of n-terminal dc domain (ndc) of ndc-ndc chimera (human doublecortin sequence) bound to 14-protofilament gdp-microtubule lattice site composed of 4 tubulin subunits (two alpha-subunits and two beta-subunits) (Complex)
- Tubulin (Complex from Bos taurus)
- Tubulin alpha-1b chain (48 kDa, Protein from Bos taurus)
- Magnesium ion (24 Da, Ligand)