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Partial DNA termination subcomplex of Xenopus laevis DNA polymerase alpha-primase
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8ucu
Q-score: 0.52
Mullins EA, Salay LE, Durie CL, Bradley NP, Jackman JE, Ohi MD, Chazin WJ, Eichman BF
Nat Struct Mol Biol (2024) 31 pp. 777-790 [ DOI: doi:10.1038/s41594-024-01227-4 Pubmed: 38491139 ]
- Dna template (18 kDa, DNA from synthetic construct)
- Dna termination substrate (30 kDa, Complex from synthetic construct)
- 2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
- Rna-dna primer (9 kDa, DNA from synthetic construct)
- Polymerase alpha-primase with a dna termination substrate (330 kDa, Complex)
- Dna polymerase alpha catalytic subunit (129 kDa, Protein from Xenopus laevis)
- Polymerase alpha (200 kDa, Complex from Xenopus laevis)
- Magnesium ion (24 Da, Ligand)
- Primase (110 kDa, Complex from Xenopus laevis)
Complete DNA termination subcomplex 1 of Xenopus laevis DNA polymerase alpha-primase
Resolution: 3.81 Å
EM Method: Single-particle
Fitted PDBs: 8ucv
Q-score: 0.337
Mullins EA, Salay LE, Durie CL, Bradley NP, Jackman JE, Ohi MD, Chazin WJ, Eichman BF
Nat Struct Mol Biol (2024) 31 pp. 777-790 [ DOI: doi:10.1038/s41594-024-01227-4 Pubmed: 38491139 ]
- Dna primase large subunit (59 kDa, Protein from Xenopus laevis)
- Dna termination substrate (30 kDa, Complex from synthetic construct)
- Dna template (18 kDa, DNA from synthetic construct)
- Iron/sulfur cluster (351 Da, Ligand)
- 2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
- Rna-dna/dna primer (9 kDa, Macromolecule from synthetic construct)
- Polymerase alpha-primase with a dna termination substrate (330 kDa, Complex)
- Dna polymerase alpha catalytic subunit (129 kDa, Protein from Xenopus laevis)
- Polymerase alpha (200 kDa, Complex from Xenopus laevis)
- Magnesium ion (24 Da, Ligand)
- Primase (110 kDa, Complex from Xenopus laevis)
Complete DNA termination subcomplex 2 of Xenopus laevis DNA polymerase alpha-primase
Resolution: 3.64 Å
EM Method: Single-particle
Fitted PDBs: 8ucw
Q-score: 0.377
Mullins EA, Salay LE, Durie CL, Bradley NP, Jackman JE, Ohi MD, Chazin WJ, Eichman BF
Nat Struct Mol Biol (2024) 31 pp. 777-790 [ DOI: doi:10.1038/s41594-024-01227-4 Pubmed: 38491139 ]
- Dna template (18 kDa, DNA from synthetic construct)
- Dna termination substrate (30 kDa, Complex from synthetic construct)
- 2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
- Rna-dna/dna primer (9 kDa, Macromolecule from synthetic construct)
- Polymerase alpha-primase with a dna termination substrate (330 kDa, Complex)
- Dna polymerase alpha catalytic subunit (129 kDa, Protein from Xenopus laevis)
- Polymerase alpha (200 kDa, Complex from Xenopus laevis)
- Magnesium ion (24 Da, Ligand)
- Primase (110 kDa, Complex from Xenopus laevis)
Partial DNA termination subcomplex of Xenopus laevis DNA polymerase alpha-primase
Mullins EA, Salay LE, Durie CL, Jackman JE, Ohi MD, Chazin WJ, Eichman BF
bioRxiv (2023) [ Pubmed: 36993335 DOI: doi:10.1101/2023.03.16.533013 ]
- Dna termination substrate (30 kDa, Complex from synthetic construct)
- Rna-dna primer (DNA from synthetic construct)
- Dna template (DNA from synthetic construct)
- Polymerase alpha-primase with a dna termination substrate (330 kDa, Complex)
- Polymerase alpha (200 kDa, Complex from Xenopus laevis)
- Pola1 (Protein from Xenopus laevis)
- Primase (110 kDa, Complex from Xenopus laevis)