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Resolution: 3.28 Å
EM Method: Single-particle
Fitted PDBs: 8ekk
Q-score: 0.538
Abeyawardhane DL, Adipietro KA, Ruiz RG, Varney KM, Rustandi RR, Silin VI, Pozharski E, Weber DJ
To Be Published
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8ekl
Q-score: 0.577
Abeyawardhane DL, Adipietro KA, Ruiz RG, Varney KM, Rustandi RR, Silin VI, Pozharski E, Weber DJ
To Be Published
Clostridioides difficile binary toxin translocase CDTb double mutant - D623A D734A
Resolution: 3.56 Å
EM Method: Single-particle
Fitted PDBs: 8ekm
Q-score: 0.502
Abeyawardhane DL, Adipietro KA, Ruiz RG, Varney KM, Rustandi RR, Silin VI, Pozharski E, Weber DJ
To Be Published
Resolution: 2.56 Å
EM Method: Single-particle
Fitted PDBs: 7vnj
Q-score: 0.536
Kawamoto A, Yamada T, Yoshida T, Sato Y, Kato T, Tsuge H
Nat Commun (2022) 13 pp. 6119-6119 [ DOI: doi:10.1038/s41467-022-33888-4 Pubmed: 36253419 ]
- Cdta (Complex)
- Adp-ribosyltransferase enzymatic component (49 kDa, Protein from Clostridioides difficile)
- Calcium ion (40 Da, Ligand)
- Cdtb (Complex from Clostridioides difficile)
- Adp-ribosylating binary toxin binding subunit cdtb (75 kDa, Protein from Clostridioides difficile)
- Cdta-bound cdtb-pore (long) (Complex from Clostridioides difficile)
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 7vnn
Q-score: 0.529
Kawamoto A, Yamada T, Yoshida T, Sato Y, Kato T, Tsuge H
Nat Commun (2022) 13 pp. 6119-6119 [ DOI: doi:10.1038/s41467-022-33888-4 Pubmed: 36253419 ]
- Calcium ion (40 Da, Ligand)
- Cdtb-pore (Complex from Clostridioides difficile)
- Cdta (Complex)
- Adp-ribosylating binary toxin binding subunit cdtb (75 kDa, Protein from Clostridioides difficile)
- Cdta (49 kDa, Protein from Clostridioides difficile)
- Cdta-bound cdtb-pore (long) (Complex from Clostridioides difficile)
Kawamoto A, Yamada T, Yoshida T, Sato Y, Kato T, Tsuge H
Nat Commun (2022) 13 pp. 6119-6119 [ DOI: doi:10.1038/s41467-022-33888-4 Pubmed: 36253419 ]
Complex structure of Clostridioides difficile binary toxin folded CDTa-bound CDTb-pore (short).
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 7yvq
Q-score: 0.494
Kawamoto A, Yamada T, Yoshida T, Sato Y, Kato T, Tsuge H
Nat Commun (2022) 13 pp. 6119-6119 [ DOI: doi:10.1038/s41467-022-33888-4 Pubmed: 36253419 ]
- Clostridioides difficile transferase complex (Complex from Clostridioides difficile)
- Adp-ribosylating binary toxin binding subunit cdtb (75 kDa, Protein from Clostridioides difficile)
- Adp-ribosylating binary toxin enzymatic subunit cdta (49 kDa, Protein from Clostridioides difficile)
- Calcium ion (40 Da, Ligand)
Complex structure of Clostridioides difficile binary toxin unfolded CDTa-bound CDTb-pore (short).
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7yvs
Q-score: 0.549
Kawamoto A, Yamada T, Yoshida T, Sato Y, Kato T, Tsuge H
Nat Commun (2022) 13 pp. 6119-6119 [ DOI: doi:10.1038/s41467-022-33888-4 Pubmed: 36253419 ]
- Clostridioides difficile transferase complex (Complex from Clostridioides difficile)
- Adp-ribosylating binary toxin binding subunit cdtb (75 kDa, Protein from Clostridioides difficile)
- Adp-ribosylating binary toxin enzymatic subunit cdta (49 kDa, Protein from Clostridioides difficile)
- Calcium ion (40 Da, Ligand)
Clostridium difficile binary toxin translocase CDTb in asymmetric tetradecamer conformation
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6uwr
Q-score: 0.594
Xu X, Godoy-Ruiz R, Adipietro KA, Peralta C, Ben-Hail D, Varney KM, Cook ME, Roth BM, Wilder PT, Cleveland T, Grishaev A, Neu HM, Michel SLJ, Yu W, Beckett D, Rustandi RR, Lancaster C, Loughney JW, Kristopeit A, Christanti S, Olson JW, MacKerell AD, Georges AD, Pozharski E, Weber DJ
PNAS (2020) 117 pp. 1049-1058 [ DOI: doi:10.1073/pnas.1919490117 Pubmed: 31896582 ]
- Calcium ion (40 Da, Ligand)
- Adp-ribosyltransferase binding component (74 kDa, Protein from Clostridioides difficile)
- Tetradecamer of cdtb (1 MDa, Complex from Clostridioides difficile)
Clostridium difficile binary toxin translocase CDTb tetradecamer in symmetric conformation
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6uwt
Q-score: 0.472
Xu X, Godoy-Ruiz R, Adipietro KA, Peralta C, Ben-Hail D, Varney KM, Cook ME, Roth BM, Wilder PT, Cleveland T, Grishaev A, Neu HM, Michel SLJ, Yu W, Beckett D, Rustandi RR, Lancaster C, Loughney JW, Kristopeit A, Christanti S, Olson JW, MacKerell AD, Georges AD, Pozharski E, Weber DJ
PNAS (2020) 117 pp. 1049-1058 [ DOI: doi:10.1073/pnas.1919490117 Pubmed: 31896582 ]
- Calcium ion (40 Da, Ligand)
- Adp-ribosyltransferase binding component (74 kDa, Protein from Clostridioides difficile)
- Cdtb tetradecamer (1 MDa, Complex from Clostridioides difficile)