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was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

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perform basic research in molecular biology

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offer vital services to scientists in the member states

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scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"40S ribosomal protein eS1"

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EMD-35634

Download Map 3D View

Wheat 80S ribosome stalled on AUG-Stop boron dependently

Release date: Feb. 21, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8ip8
Q-score: 0.579

Tanaka M, Yokoyama T, Saito H, Nishimoto M, Tsuda K, Sotta N, Shigematsu H, Shirouzu M, Iwasaki S, Ito T, Fujiwara T

Nat Chem Biol (2024) 20 pp. 605-614 [ Pubmed: 38267667 DOI: doi:10.1038/s41589-023-01513-0 ]

Sample:

40s ribosomal protein us11 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein es17 (16 kDa, Protein from Triticum aestivum)
60s ribosomal protein el6 (24 kDa, Protein from Triticum aestivum)
40s ribosomal protein us15 (17 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul5 (20 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul6 (21 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul22 (19 kDa, Protein from Triticum aestivum)
40s ribosomal protein el8 (29 kDa, Protein from Triticum aestivum)
60s ribosomal protein el21 (18 kDa, Protein from Triticum aestivum)
60s ribosomal protein el40 (14 kDa, Protein from Triticum aestivum)
60s ribosomal protein el34 (13 kDa, Protein from Triticum aestivum)
40s ribosomal protein us19 (17 kDa, Protein from Triticum aestivum)
40s ribosomal protein us8 (14 kDa, Protein from Triticum aestivum)
60s ribosomal rna (1 MDa, RNA from Triticum aestivum)
60s ribosomal protein el18 (21 kDa, Protein from Triticum aestivum)
60s ribosomal protein el41 (3 kDa, Protein from Oryza sativa)
60s ribosomal protein ul3 (44 kDa, Protein from Triticum aestivum)
60s ribosomal protein el31 (14 kDa, Protein from Triticum aestivum)
60s ribosomal protein el38 (8 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul15 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein es4 (30 kDa, Protein from Triticum aestivum)
40s ribosomal protein es25 (12 kDa, Protein from Triticum aestivum)
Wheat 80s ribosome stalled on aug-stop boron dependently (Complex from Triticum aestivum)
40s ribosomal protein es1 (30 kDa, Protein from Triticum aestivum)
60s ribosomal protein el29 (6 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul13 (23 kDa, Protein from Triticum aestivum)
60s ribosomal protein el33 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein es10 (20 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul2 (28 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul29 (14 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul23 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein us13 (17 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul4 (44 kDa, Protein from Triticum aestivum)
40s ribosomal protein us17 (17 kDa, Protein from Triticum aestivum)
40s ribosomal protein us10 (14 kDa, Protein from Triticum aestivum)
5.8s ribosomal rna (51 kDa, RNA from Triticum aestivum)
60s ribosomal protein el24 (18 kDa, Protein from Triticum aestivum)
40s ribosomal protein us4 (22 kDa, Protein from Triticum aestivum)
40s ribosomal protein es28 (9 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul30 (28 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul18 (34 kDa, Protein from Triticum aestivum)
60s ribosomal protein el30 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein us5 (29 kDa, Protein from Triticum aestivum)
60s ribosomal protein el37 (10 kDa, Protein from Triticum aestivum)
40s ribosomal protein es26 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein es19 (17 kDa, Protein from Triticum aestivum)
60s ribosomal protein el20 (21 kDa, Protein from Triticum aestivum)
Eukaryotic release factor 1 (49 kDa, Protein from Triticum aestivum)
60s ribosomal protein el14 (15 kDa, Protein from Triticum aestivum)
Rack1 (36 kDa, Protein from Triticum aestivum)
40s ribosomal protein es7 (22 kDa, Protein from Triticum aestivum)
60s ribosomal protein el42 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein us2 (33 kDa, Protein from Triticum aestivum)
40s ribosomal protein us9 (16 kDa, Protein from Triticum aestivum)
60s ribosomal protein el27 (15 kDa, Protein from Triticum aestivum)
40s ribosomal protein us14 (6 kDa, Protein from Triticum aestivum)
60s ribosomal protein el36 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein es6 (28 kDa, Protein from Triticum aestivum)
60s ribosomal protein el43 (10 kDa, Protein from Triticum aestivum)
5s ribosomal rna (38 kDa, RNA from Triticum aestivum)
Magnesium ion (24 Da, Ligand)
40s ribosomal protein us3 (25 kDa, Protein from Triticum aestivum)
18s ribosomal rna (583 kDa, RNA from Triticum aestivum)
60s ribosomal protein el39 (9 kDa, Protein from Triticum aestivum)
40s ribosomal protein us12 (15 kDa, Protein from Triticum aestivum)
40s ribosomal protein es30 (6 kDa, Protein from Triticum aestivum)
60s ribosomal protein el28 (16 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul16 (24 kDa, Protein from Triticum aestivum)
40s ribosomal protein es8 (25 kDa, Protein from Triticum aestivum)
60s ribosomal protein el19 (24 kDa, Protein from Triticum aestivum)
40s ribosomal protein es21 (9 kDa, Protein from Triticum aestivum)
40s ribosomal protein es27 (9 kDa, Protein from Triticum aestivum)
40s ribosomal protein es24 (15 kDa, Protein from Triticum aestivum)
60s ribosomal protein el15 (24 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul14 (15 kDa, Protein from Triticum aestivum)
Zinc ion (65 Da, Ligand)
60s ribosomal protein ul24 (17 kDa, Protein from Triticum aestivum)
60s ribosomal protein el22 (14 kDa, Protein from Triticum aestivum)
60s ribosomal protein el13 (24 kDa, Protein from Triticum aestivum)
Cca end of e-trna (894 Da, RNA from Triticum aestivum)
Trnai (24 kDa, RNA from Triticum aestivum)
60s ribosomal protein el32 (15 kDa, Protein from Triticum aestivum)
Mrna (2 kDa, RNA from Triticum aestivum)
40s ribosomal protein us7 (22 kDa, Protein from Triticum aestivum)

[Show more]

EMD-35635

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Wheat 40S ribosome in complex with a tRNAi

Release date: Feb. 21, 2024
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8ip9
Q-score: 0.53

Tanaka M, Yokoyama T, Saito H, Nishimoto M, Tsuda K, Sotta N, Shigematsu H, Shirouzu M, Iwasaki S, Ito T, Fujiwara T

Nat Chem Biol (2024) 20 pp. 605-614 [ Pubmed: 38267667 DOI: doi:10.1038/s41589-023-01513-0 ]

Sample:

40s ribosomal protein us11 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein es17 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein es1 (30 kDa, Protein from Triticum aestivum)
40s ribosomal protein us15 (17 kDa, Protein from Triticum aestivum)
Wheat 40s ribosome in complex with a trnai (Complex from Triticum aestivum)
40s ribosomal protein es10 (20 kDa, Protein from Triticum aestivum)
40s ribosomal protein es8 (25 kDa, Protein from Triticum aestivum)
Rack1 (36 kDa, Protein from Triticum aestivum)
40s ribosomal protein es21 (9 kDa, Protein from Triticum aestivum)
40s ribosomal protein es7 (22 kDa, Protein from Triticum aestivum)
40s ribosomal protein es27 (9 kDa, Protein from Triticum aestivum)
40s ribosomal protein es24 (15 kDa, Protein from Triticum aestivum)
40s ribosomal protein us19 (17 kDa, Protein from Triticum aestivum)
40s ribosomal protein us2 (33 kDa, Protein from Triticum aestivum)
40s ribosomal protein us8 (14 kDa, Protein from Triticum aestivum)
40s ribosomal protein us9 (16 kDa, Protein from Triticum aestivum)
Zinc ion (65 Da, Ligand)
40s ribosomal protein us13 (17 kDa, Protein from Triticum aestivum)
40s ribosomal protein us14 (6 kDa, Protein from Triticum aestivum)
40s ribosomal protein es6 (28 kDa, Protein from Triticum aestivum)
40s ribosomal protein us17 (17 kDa, Protein from Triticum aestivum)
40s ribosomal protein us10 (14 kDa, Protein from Triticum aestivum)
60s ribosomal protein el41 (3 kDa, Protein from Oryza sativa)
Trnai (24 kDa, RNA from Triticum aestivum)
Magnesium ion (24 Da, Ligand)
40s ribosomal protein us4 (22 kDa, Protein from Triticum aestivum)
40s ribosomal protein es28 (9 kDa, Protein from Triticum aestivum)
40s ribosomal protein us3 (25 kDa, Protein from Triticum aestivum)
18s ribosomal rna (583 kDa, RNA from Triticum aestivum)
Mrna (2 kDa, RNA from Triticum aestivum)
40s ribosomal protein es30 (6 kDa, Protein from Triticum aestivum)
40s ribosomal protein es4 (30 kDa, Protein from Triticum aestivum)
40s ribosomal protein es25 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein us7 (22 kDa, Protein from Triticum aestivum)
40s ribosomal protein us5 (29 kDa, Protein from Triticum aestivum)
40s ribosomal protein s23 (15 kDa, Protein from Triticum aestivum)
40s ribosomal protein es26 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein es19 (17 kDa, Protein from Triticum aestivum)

[Show more]

EMD-35637

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Wheat 80S ribosome stalled on AUG-Stop boron dependently with cycloheximide

Release date: Feb. 21, 2024
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8ipa
Q-score: 0.471

Tanaka M, Yokoyama T, Saito H, Nishimoto M, Tsuda K, Sotta N, Shigematsu H, Shirouzu M, Iwasaki S, Ito T, Fujiwara T

Nat Chem Biol (2024) 20 pp. 605-614 [ Pubmed: 38267667 DOI: doi:10.1038/s41589-023-01513-0 ]

Sample:

40s ribosomal protein us11 (16 kDa, Protein from Triticum aestivum)
Wheat 80s ribosome stalled on aug-stop boron dependently with cycloheximide (Complex from Triticum aestivum)
40s ribosomal protein es17 (16 kDa, Protein from Triticum aestivum)
60s ribosomal protein el6 (24 kDa, Protein from Triticum aestivum)
40s ribosomal protein us15 (17 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul5 (20 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul6 (21 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul22 (19 kDa, Protein from Triticum aestivum)
40s ribosomal protein el8 (29 kDa, Protein from Triticum aestivum)
60s ribosomal protein el21 (18 kDa, Protein from Triticum aestivum)
60s ribosomal protein el40 (14 kDa, Protein from Triticum aestivum)
60s ribosomal protein el34 (13 kDa, Protein from Triticum aestivum)
40s ribosomal protein us19 (17 kDa, Protein from Triticum aestivum)
40s ribosomal protein us8 (14 kDa, Protein from Triticum aestivum)
60s ribosomal rna (1 MDa, RNA from Triticum aestivum)
60s ribosomal protein el18 (21 kDa, Protein from Triticum aestivum)
60s ribosomal protein el41 (3 kDa, Protein from Oryza sativa)
60s ribosomal protein ul3 (44 kDa, Protein from Triticum aestivum)
60s ribosomal protein el31 (14 kDa, Protein from Triticum aestivum)
60s ribosomal protein el38 (8 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul15 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein es4 (30 kDa, Protein from Triticum aestivum)
40s ribosomal protein es25 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein es1 (30 kDa, Protein from Triticum aestivum)
60s ribosomal protein el29 (6 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul13 (23 kDa, Protein from Triticum aestivum)
60s ribosomal protein el33 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein es10 (20 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul2 (28 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul29 (14 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul23 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein us13 (17 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul4 (44 kDa, Protein from Triticum aestivum)
40s ribosomal protein us17 (17 kDa, Protein from Triticum aestivum)
40s ribosomal protein us10 (14 kDa, Protein from Triticum aestivum)
5.8s ribosomal rna (51 kDa, RNA from Triticum aestivum)
60s ribosomal protein el24 (18 kDa, Protein from Triticum aestivum)
40s ribosomal protein us4 (22 kDa, Protein from Triticum aestivum)
40s ribosomal protein es28 (9 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul30 (28 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul18 (34 kDa, Protein from Triticum aestivum)
60s ribosomal protein el30 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein us5 (29 kDa, Protein from Triticum aestivum)
60s ribosomal protein el37 (10 kDa, Protein from Triticum aestivum)
40s ribosomal protein es26 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein es19 (17 kDa, Protein from Triticum aestivum)
60s ribosomal protein el20 (21 kDa, Protein from Triticum aestivum)
Eukaryotic release factor 1 (49 kDa, Protein from Triticum aestivum)
60s ribosomal protein el14 (15 kDa, Protein from Triticum aestivum)
Rack1 (36 kDa, Protein from Triticum aestivum)
40s ribosomal protein es7 (22 kDa, Protein from Triticum aestivum)
60s ribosomal protein el42 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein us2 (33 kDa, Protein from Triticum aestivum)
40s ribosomal protein us9 (16 kDa, Protein from Triticum aestivum)
60s ribosomal protein el27 (15 kDa, Protein from Triticum aestivum)
40s ribosomal protein us14 (6 kDa, Protein from Triticum aestivum)
60s ribosomal protein el36 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein es6 (28 kDa, Protein from Triticum aestivum)
60s ribosomal protein el43 (10 kDa, Protein from Triticum aestivum)
5s ribosomal rna (38 kDa, RNA from Triticum aestivum)
Magnesium ion (24 Da, Ligand)
40s ribosomal protein us3 (25 kDa, Protein from Triticum aestivum)
18s ribosomal rna (583 kDa, RNA from Triticum aestivum)
60s ribosomal protein el39 (9 kDa, Protein from Triticum aestivum)
40s ribosomal protein us12 (15 kDa, Protein from Triticum aestivum)
4-{(2r)-2-[(1s,3s,5s)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione (281 Da, Ligand)
40s ribosomal protein es30 (6 kDa, Protein from Triticum aestivum)
60s ribosomal protein el28 (16 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul16 (24 kDa, Protein from Triticum aestivum)
40s ribosomal protein es8 (25 kDa, Protein from Triticum aestivum)
60s ribosomal protein el19 (24 kDa, Protein from Triticum aestivum)
40s ribosomal protein es21 (9 kDa, Protein from Triticum aestivum)
40s ribosomal protein es27 (9 kDa, Protein from Triticum aestivum)
40s ribosomal protein es24 (15 kDa, Protein from Triticum aestivum)
60s ribosomal protein el15 (24 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul14 (15 kDa, Protein from Triticum aestivum)
Zinc ion (65 Da, Ligand)
60s ribosomal protein ul24 (17 kDa, Protein from Triticum aestivum)
60s ribosomal protein el22 (14 kDa, Protein from Triticum aestivum)
60s ribosomal protein el13 (24 kDa, Protein from Triticum aestivum)
Trnai (24 kDa, RNA from Triticum aestivum)
60s ribosomal protein el32 (15 kDa, Protein from Triticum aestivum)
Mrna (2 kDa, RNA from Triticum aestivum)
40s ribosomal protein us7 (22 kDa, Protein from Triticum aestivum)

[Show more]

EMD-35638

Download Map 3D View

Wheat 80S ribosome pausing on AUG-Stop with cycloheximide

Release date: Feb. 21, 2024
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8ipb
Q-score: 0.466

Tanaka M, Yokoyama T, Saito H, Nishimoto M, Tsuda K, Sotta N, Shigematsu H, Shirouzu M, Iwasaki S, Ito T, Fujiwara T

Nat Chem Biol (2024) 20 pp. 605-614 [ Pubmed: 38267667 DOI: doi:10.1038/s41589-023-01513-0 ]

Sample:

40s ribosomal protein us11 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein es17 (16 kDa, Protein from Triticum aestivum)
60s ribosomal protein el6 (24 kDa, Protein from Triticum aestivum)
40s ribosomal protein us15 (17 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul5 (20 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul6 (21 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul22 (19 kDa, Protein from Triticum aestivum)
40s ribosomal protein el8 (29 kDa, Protein from Triticum aestivum)
60s ribosomal protein el21 (18 kDa, Protein from Triticum aestivum)
60s ribosomal protein el40 (14 kDa, Protein from Triticum aestivum)
60s ribosomal protein el34 (13 kDa, Protein from Triticum aestivum)
40s ribosomal protein us19 (17 kDa, Protein from Triticum aestivum)
40s ribosomal protein us8 (14 kDa, Protein from Triticum aestivum)
60s ribosomal rna (1 MDa, RNA from Triticum aestivum)
60s ribosomal protein el18 (21 kDa, Protein from Triticum aestivum)
60s ribosomal protein el41 (3 kDa, Protein from Oryza sativa)
60s ribosomal protein ul3 (44 kDa, Protein from Triticum aestivum)
60s ribosomal protein el31 (14 kDa, Protein from Triticum aestivum)
60s ribosomal protein el38 (8 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul15 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein es4 (30 kDa, Protein from Triticum aestivum)
40s ribosomal protein es25 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein es1 (30 kDa, Protein from Triticum aestivum)
60s ribosomal protein el29 (6 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul13 (23 kDa, Protein from Triticum aestivum)
60s ribosomal protein el33 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein es10 (20 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul2 (28 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul29 (14 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul23 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein us13 (17 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul4 (44 kDa, Protein from Triticum aestivum)
40s ribosomal protein us17 (17 kDa, Protein from Triticum aestivum)
40s ribosomal protein us10 (14 kDa, Protein from Triticum aestivum)
5.8s ribosomal rna (51 kDa, RNA from Triticum aestivum)
60s ribosomal protein el24 (18 kDa, Protein from Triticum aestivum)
40s ribosomal protein us4 (22 kDa, Protein from Triticum aestivum)
40s ribosomal protein es28 (9 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul30 (28 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul18 (34 kDa, Protein from Triticum aestivum)
60s ribosomal protein el30 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein us5 (29 kDa, Protein from Triticum aestivum)
60s ribosomal protein el37 (10 kDa, Protein from Triticum aestivum)
40s ribosomal protein es26 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein es19 (17 kDa, Protein from Triticum aestivum)
60s ribosomal protein el20 (21 kDa, Protein from Triticum aestivum)
60s ribosomal protein el14 (15 kDa, Protein from Triticum aestivum)
Rack1 (36 kDa, Protein from Triticum aestivum)
40s ribosomal protein es7 (22 kDa, Protein from Triticum aestivum)
60s ribosomal protein el42 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein us2 (33 kDa, Protein from Triticum aestivum)
40s ribosomal protein us9 (16 kDa, Protein from Triticum aestivum)
60s ribosomal protein el27 (15 kDa, Protein from Triticum aestivum)
40s ribosomal protein us14 (6 kDa, Protein from Triticum aestivum)
60s ribosomal protein el36 (12 kDa, Protein from Triticum aestivum)
40s ribosomal protein es6 (28 kDa, Protein from Triticum aestivum)
60s ribosomal protein el43 (10 kDa, Protein from Triticum aestivum)
5s ribosomal rna (38 kDa, RNA from Triticum aestivum)
Magnesium ion (24 Da, Ligand)
40s ribosomal protein us3 (25 kDa, Protein from Triticum aestivum)
18s ribosomal rna (583 kDa, RNA from Triticum aestivum)
60s ribosomal protein el39 (9 kDa, Protein from Triticum aestivum)
40s ribosomal protein us12 (15 kDa, Protein from Triticum aestivum)
4-{(2r)-2-[(1s,3s,5s)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione (281 Da, Ligand)
40s ribosomal protein es30 (6 kDa, Protein from Triticum aestivum)
60s ribosomal protein el28 (16 kDa, Protein from Triticum aestivum)
Wheat 80s ribosome pausing on aug-stop with cycloheximide (Complex from Triticum aestivum)
60s ribosomal protein ul16 (24 kDa, Protein from Triticum aestivum)
40s ribosomal protein es8 (25 kDa, Protein from Triticum aestivum)
60s ribosomal protein el19 (24 kDa, Protein from Triticum aestivum)
40s ribosomal protein es21 (9 kDa, Protein from Triticum aestivum)
40s ribosomal protein es27 (9 kDa, Protein from Triticum aestivum)
40s ribosomal protein es24 (15 kDa, Protein from Triticum aestivum)
60s ribosomal protein el15 (24 kDa, Protein from Triticum aestivum)
60s ribosomal protein ul14 (15 kDa, Protein from Triticum aestivum)
Zinc ion (65 Da, Ligand)
60s ribosomal protein ul24 (17 kDa, Protein from Triticum aestivum)
60s ribosomal protein el22 (14 kDa, Protein from Triticum aestivum)
60s ribosomal protein el13 (24 kDa, Protein from Triticum aestivum)
Trnai (24 kDa, RNA from Triticum aestivum)
60s ribosomal protein el32 (15 kDa, Protein from Triticum aestivum)
Mrna (2 kDa, RNA from Triticum aestivum)
40s ribosomal protein us7 (22 kDa, Protein from Triticum aestivum)

[Show more]

EMD-10760

Download Map 3D View

Mammalian 48S late-stage initiation complex with beta-globin mRNA

Release date: April 8, 2020
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6yal
Q-score: 0.379

Simonetti A, Guca E, Bochler A, Kuhn L, Hashem Y

Cell Rep (2020) 31 pp. 107497-107497 [ Pubmed: 32268096 DOI: doi:10.1016/j.celrep.2020.03.061 ]

Sample:

40s ribosomal protein us2 (23 kDa, Protein from Rabbit)
Ribosomal protein rack1 (34 kDa, Protein from Rabbit)
40s ribosomal protein es1 (29 kDa, Protein from Rabbit)
40s ribosomal protein es7 (21 kDa, Protein from Rabbit)
Beta-globin mrna (Complex from Homo sapiens)
40s ribosomal protein us7 (21 kDa, Protein from Rabbit)
Ls48s ic with beta-globin mrna (Complex)
40s ribosomal protein us8 (14 kDa, Protein from Rabbit)
40s ribosomal protein es28 (7 kDa, Protein from Rabbit)
Eukaryotic translation initiation factor 1a (12 kDa, Protein from Rabbit)
Ls48s ic (Complex from Oryctolagus cuniculus)
40s ribosomal protein es19 (15 kDa, Protein from Rabbit)
40s ribosomal protein es26 (12 kDa, Protein from Rabbit)
40s ribosomal protein es30 (14 kDa, Protein from Rabbit)
40s ribosomal protein es10 (11 kDa, Protein from Rabbit)
40s ribosomal protein us17 (18 kDa, Protein from Rabbit)
Beta-globin mrna (13 kDa, RNA from Homo sapiens)
40s ribosomal protein us11 (16 kDa, Protein from Rabbit)
40s ribosomal protein es27 (9 kDa, Protein from Rabbit)
40s ribosomal protein es6 (27 kDa, Protein from Rabbit)
40s ribosomal protein us19 (17 kDa, Protein from Rabbit)
40s ribosomal protein us5 (24 kDa, Protein from Rabbit)
40s ribosomal protein us10 (13 kDa, Protein from Rabbit)
40s ribosomal protein es21 (8 kDa, Protein from Rabbit)
40s ribosomal protein us3 (26 kDa, Protein from Rabbit)
40s ribosomal protein us9 (15 kDa, Protein from Rabbit)
40s ribosomal protein us14 (6 kDa, Protein from Rabbit)
Eukaryotic translation initiation factor 2 subunit alpha (32 kDa, Protein from Rabbit)
40s ribosomal protein us12 (15 kDa, Protein from Rabbit)
40s ribosomal protein es4 (29 kDa, Protein from Rabbit)
40s ribosomal protein es8 (23 kDa, Protein from Rabbit)
40s ribosomal protein us15 (17 kDa, Protein from Rabbit)
Initiator methionylated trna (24 kDa, RNA from Rabbit)
Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
40s ribosomal protein es24 (15 kDa, Protein from Rabbit)
Magnesium ion (24 Da, Ligand)
Atp-binding cassette sub-family e member 1 (abce1) (66 kDa, Protein from Rabbit)
40s ribosomal protein es25 (13 kDa, Protein from Rabbit)
40s ribosomal protein es12 (14 kDa, Protein from Rabbit)
40s ribosomal protein us13 (17 kDa, Protein from Rabbit)
60s ribosomal protein ul41 (3 kDa, Protein from Rabbit)
40s ribosomal protein es17 (15 kDa, Protein from Rabbit)
Eukaryotic translation initiation factor 2 subunit gamma (45 kDa, Protein from Rabbit)
40s ribosomal protein es31 (8 kDa, Protein from Rabbit)
18s ribosomal rna (601 kDa, RNA from Rabbit)
40s ribosomal protein us4 (21 kDa, Protein from Rabbit)
Iron/sulfur cluster (351 Da, Ligand)

[Show more]

EMD-10761

Download Map 3D View

Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA

Release date: April 8, 2020
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6yam
Q-score: 0.257

Simonetti A, Guca E, Bochler A, Kuhn L, Hashem Y

Cell Rep (2020) 31 pp. 107497-107497 [ Pubmed: 32268096 DOI: doi:10.1016/j.celrep.2020.03.061 ]

Sample:

Eukaryotic translation initiation factor 3 subunit a (163 kDa, Protein from Rabbit)
40s ribosomal protein us2 (23 kDa, Protein from Rabbit)
Ribosomal protein rack1 (34 kDa, Protein from Rabbit)
40s ribosomal protein es1 (29 kDa, Protein from Rabbit)
Eukaryotic translation initiation factor 2 subunit alpha (30 kDa, Protein from Rabbit)
60s ribosomal protein l41 (3 kDa, Protein from Rabbit)
Eukaryotic translation initiation factor 3 subunit e (52 kDa, Protein from Rabbit)
Beta-globin mrna (Complex from Homo sapiens)
Ls48s+eif3 ic with beta-globin mrna (Complex)
40s ribosomal protein us8 (14 kDa, Protein from Rabbit)
40s ribosomal protein es28 (7 kDa, Protein from Rabbit)
40s ribosomal protein es26 (12 kDa, Protein from Rabbit)
40s ribosomal protein es10 (11 kDa, Protein from Rabbit)
40s ribosomal protein us17 (18 kDa, Protein from Rabbit)
40s ribosomal protein us12 (15 kDa, Protein from Rabbit)
Ribosomal protein us14 (6 kDa, Protein from Rabbit)
40s ribosomal protein us11 (16 kDa, Protein from Rabbit)
40s ribosomal protein es27 (9 kDa, Protein from Rabbit)
Ribosomal protein es25 (8 kDa, Protein from Rabbit)
40s ribosomal protein es6 (27 kDa, Protein from Rabbit)
Ls48s+eif3 ic (Complex from Oryctolagus cuniculus)
Eukaryotic translation initiation factor 2 subunit gamma (45 kDa, Protein from Rabbit)
Eukaryotic translation initiation factor 3 subunit h (39 kDa, Protein from Rabbit)
Eukaryotic translation initiation factor 3 subunit k (25 kDa, Protein from Rabbit)
40s ribosomal protein us19 (17 kDa, Protein from Rabbit)
Eukaryotic translation initiation factor 3 subunit l (66 kDa, Protein from Rabbit)
Eukaryotic translation initiation factor 3 subunit m (42 kDa, Protein from Rabbit)
Eukaryotic translation initiation factor 1a (16 kDa, Protein from Rabbit)
40s ribosomal protein us5 (24 kDa, Protein from Rabbit)
40s ribosomal protein es19 (16 kDa, Protein from Rabbit)
Ribosomal protein es31 (8 kDa, Protein from Rabbit)
40s ribosomal protein us10 (13 kDa, Protein from Rabbit)
40s ribosomal protein es21 (8 kDa, Protein from Rabbit)
40s ribosomal protein us9 (15 kDa, Protein from Rabbit)
Eukaryotic translation initiation factor 3 subunit f (30 kDa, Protein from Rabbit)
40s ribosomal protein es4 (29 kDa, Protein from Rabbit)
40s ribosomal protein es8 (23 kDa, Protein from Rabbit)
Initiator methionylated trna (24 kDa, RNA from Rabbit)
Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
40s ribosomal protein es24 (15 kDa, Protein from Rabbit)
Magnesium ion (24 Da, Ligand)
Atp-binding cassette sub-family e member 1 (abce1) (66 kDa, Protein from Rabbit)
Ribosomal protein us15 (17 kDa, Protein from Rabbit)
40s ribosomal protein es12 (14 kDa, Protein from Rabbit)
40s ribosomal protein es30 (6 kDa, Protein from Rabbit)
40s ribosomal protein us13 (17 kDa, Protein from Rabbit)
40s ribosomal protein es17 (15 kDa, Protein from Rabbit)
Beta-globin mrna (14 kDa, RNA from Homo sapiens)
40s ribosomal protein us7 (21 kDa, Protein from Rabbit)
Ribosomal protein es7 (21 kDa, Protein from Rabbit)
40s ribosomal protein us3 (25 kDa, Protein from Rabbit)
Eukaryotic translation initiation factor 3 subunit d (64 kDa, Protein from Rabbit)
18s ribosomal rna (601 kDa, RNA from Rabbit)
40s ribosomal protein us4 (21 kDa, Protein from Rabbit)
Eukaryotic translation initiation factor 3 subunit c (105 kDa, Protein from Rabbit)
Iron/sulfur cluster (351 Da, Ligand)

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