Electron Microscopy Data Bank

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sample_name:"28S ribosomal protein S18c, mitochondrial"

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EMD-15544

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Human mitochondrial ribosome in complex with LRPPRC, SLIRP, A-site, P-site, E-site tRNAs and mRNA

Release date: Aug. 16, 2023
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8any
Q-score: 0.554

Singh V, Conor J, Itoh Y, Soto T, Fontanesi F, Couvillian M, Huynen M, Churchman S, Barrientos A, Amunts A

To Be Published

Sample:

28s ribosomal protein s26, mitochondrial (24 kDa, Protein from Homo sapiens)
39s ribosomal protein l12, mitochondrial (21 kDa, Protein from Homo sapiens)
39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Homo sapiens)
28s ribosomal protein s11, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Homo sapiens)
28s ribosomal protein s12, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s24, mitochondrial (19 kDa, Protein from Homo sapiens)
28s ribosomal protein s29, mitochondrial (45 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
39s ribosomal protein l1, mitochondrial (36 kDa, Protein from Homo sapiens)
16s mitochondrial rrna (500 kDa, RNA from Homo sapiens)
39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Homo sapiens)
39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Homo sapiens)
Valine (117 Da, Ligand)
39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Homo sapiens)
39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Homo sapiens)
Spermine (202 Da, Ligand)
39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Homo sapiens)
Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Homo sapiens)
28s ribosomal protein s16, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s14, mitochondrial (15 kDa, Protein from Homo sapiens)
Sra stem-loop-interacting rna-binding protein, mitochondrial (12 kDa, Protein from Homo sapiens)
28s ribosomal protein s2, mitochondrial (33 kDa, Protein from Homo sapiens)
39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Homo sapiens)
39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Homo sapiens)
Ribosomal protein 63, mitochondrial (12 kDa, Protein from Homo sapiens)
Guanosine-5'-diphosphate (443 Da, Ligand)
28s ribosomal protein s6, mitochondrial (14 kDa, Protein from Homo sapiens)
Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Homo sapiens)
39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Homo sapiens)
39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Homo sapiens)
39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Homo sapiens)
28s ribosomal protein s18c, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s31, mitochondrial (45 kDa, Protein from Homo sapiens)
39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Homo sapiens)
Water (18 Da, Ligand)
39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Homo sapiens)
28s ribosomal protein s17, mitochondrial (14 kDa, Protein from Homo sapiens)
39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Homo sapiens)
39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Homo sapiens)
Spermidine (145 Da, Ligand)
39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Homo sapiens)
28s ribosomal protein s15, mitochondrial (29 kDa, Protein from Homo sapiens)
39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Homo sapiens)
1,4-diaminobutane (88 Da, Ligand)
E/e-trna (22 kDa, RNA from Homo sapiens)
39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Homo sapiens)
39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Homo sapiens)
39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Homo sapiens)
39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Homo sapiens)
Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
A/a-trna (21 kDa, RNA from Homo sapiens)
Mitochondrial trnaval (22 kDa, RNA from Homo sapiens)
28s ribosomal protein s9, mitochondrial (45 kDa, Protein from Homo sapiens)
39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Homo sapiens)
39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Homo sapiens)
28s ribosomal protein s28, mitochondrial (20 kDa, Protein from Homo sapiens)
28s ribosomal protein s22, mitochondrial (41 kDa, Protein from Homo sapiens)
39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Homo sapiens)
Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 (13 kDa, Protein from Homo sapiens)
P/p-trna (22 kDa, RNA from Homo sapiens)
39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Homo sapiens)
39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Homo sapiens)
39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Homo sapiens)
Pentatricopeptide repeat domain-containing protein 3, mitochondrial (78 kDa, Protein from Homo sapiens)
39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Homo sapiens)
39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Homo sapiens)
28s ribosomal protein s25, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Homo sapiens)
28s ribosomal protein s5, mitochondrial (48 kDa, Protein from Homo sapiens)
28s ribosomal protein s18b, mitochondrial (29 kDa, Protein from Homo sapiens)
39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s23, mitochondrial (21 kDa, Protein from Homo sapiens)
28s ribosomal protein s21, mitochondrial (10 kDa, Protein from Homo sapiens)
Leucine-rich ppr motif-containing protein, mitochondrial (158 kDa, Protein from Homo sapiens)
28s ribosomal protein s34, mitochondrial (25 kDa, Protein from Homo sapiens)
28s ribosomal protein s27, mitochondrial (47 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Homo sapiens)
39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Homo sapiens)
28s ribosomal protein s7, mitochondrial (28 kDa, Protein from Homo sapiens)
12s mitochondrial rrna (306 kDa, RNA from Homo sapiens)
39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Homo sapiens)
28s ribosomal protein s10, mitochondrial (23 kDa, Protein from Homo sapiens)
28s ribosomal protein s35, mitochondrial (36 kDa, Protein from Homo sapiens)
28s ribosomal protein s33, mitochondrial (12 kDa, Protein from Homo sapiens)
39s ribosomal protein l36, mitochondrial (11 kDa, Protein from Homo sapiens)
Potassium ion (39 Da, Ligand from Homo sapiens)
Mrna (13 kDa, RNA from Homo sapiens)
Human mitochondrial ribosome bound to lrpprc-slirp, mrna and trnas in the a-site, p-site and e-site (Complex from Homo sapiens)
39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Homo sapiens)
39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Homo sapiens)
Aurora kinase a-interacting protein (22 kDa, Protein from Homo sapiens)
39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Homo sapiens)
39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Homo sapiens)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)

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EMD-13981

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Human mitochondrial ribosome in complex with mRNA, A/A-, P/P- and E/E-tRNAs at 2.63 A resolution

Release date: July 5, 2023
Resolution: 2.63 Å
EM Method: Single-particle
Fitted PDBs: 7qi5
Q-score: 0.594

Singh V, Itoh Y, Del'Olio S, Hassan A, Naschberger A, Flygaard RK, Nobe Y, Izumikawa K, Aibara S, Andrell J, Whitford PC, Barrientos A, Taoka M, Amunts A

bioRxiv (2023) [ Pubmed: 37503168 DOI: doi:10.1101/2023.05.24.542018 ]

Sample:

28s ribosomal protein s26, mitochondrial (24 kDa, Protein from Homo sapiens)
39s ribosomal protein l12, mitochondrial (21 kDa, Protein from Homo sapiens)
39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Homo sapiens)
28s ribosomal protein s11, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Homo sapiens)
28s ribosomal protein s12, mitochondrial (15 kDa, Protein from Homo sapiens)
Mrna (10 kDa, RNA from Homo sapiens)
28s ribosomal protein s24, mitochondrial (19 kDa, Protein from Homo sapiens)
28s ribosomal protein s29, mitochondrial (45 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
39s ribosomal protein l1, mitochondrial (36 kDa, Protein from Homo sapiens)
16s mitochondrial rrna (500 kDa, RNA from Homo sapiens)
39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Homo sapiens)
39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Homo sapiens)
Valine (117 Da, Ligand)
39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Homo sapiens)
39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Homo sapiens)
Spermine (202 Da, Ligand)
39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Homo sapiens)
Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Homo sapiens)
28s ribosomal protein s16, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s14, mitochondrial (15 kDa, Protein from Homo sapiens)
Potassium ion (39 Da, Ligand)
28s ribosomal protein s2, mitochondrial (33 kDa, Protein from Homo sapiens)
39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Homo sapiens)
39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Homo sapiens)
Ribosomal protein 63, mitochondrial (12 kDa, Protein from Homo sapiens)
Guanosine-5'-diphosphate (443 Da, Ligand)
28s ribosomal protein s6, mitochondrial (14 kDa, Protein from Homo sapiens)
Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Homo sapiens)
39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Homo sapiens)
39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Homo sapiens)
39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Homo sapiens)
28s ribosomal protein s31, mitochondrial (45 kDa, Protein from Homo sapiens)
28s ribosomal protein s18c, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Homo sapiens)
Water (18 Da, Ligand)
39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Homo sapiens)
28s ribosomal protein s17, mitochondrial (14 kDa, Protein from Homo sapiens)
39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Homo sapiens)
39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Homo sapiens)
Spermidine (145 Da, Ligand)
39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Homo sapiens)
28s ribosomal protein s15, mitochondrial (29 kDa, Protein from Homo sapiens)
39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Homo sapiens)
1,4-diaminobutane (88 Da, Ligand)
E/e-trna (22 kDa, RNA from Homo sapiens)
39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Homo sapiens)
39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Homo sapiens)
39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Homo sapiens)
39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Homo sapiens)
Human mitochondrial ribosome (Complex from Homo sapiens)
Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
A/a-trna (21 kDa, RNA from Homo sapiens)
Mitochondrial trnaval (22 kDa, RNA from Homo sapiens)
28s ribosomal protein s9, mitochondrial (45 kDa, Protein from Homo sapiens)
39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Homo sapiens)
39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Homo sapiens)
28s ribosomal protein s28, mitochondrial (20 kDa, Protein from Homo sapiens)
28s ribosomal protein s22, mitochondrial (41 kDa, Protein from Homo sapiens)
39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Homo sapiens)
Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 (13 kDa, Protein from Homo sapiens)
P/p-trna (22 kDa, RNA from Homo sapiens)
Mrps21 isoform 1 (10 kDa, Protein from Homo sapiens)
39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Homo sapiens)
39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Homo sapiens)
Pentatricopeptide repeat domain-containing protein 3, mitochondrial (78 kDa, Protein from Homo sapiens)
39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Homo sapiens)
39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Homo sapiens)
28s ribosomal protein s25, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Homo sapiens)
28s ribosomal protein s5, mitochondrial (48 kDa, Protein from Homo sapiens)
28s ribosomal protein s18b, mitochondrial (29 kDa, Protein from Homo sapiens)
39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s23, mitochondrial (21 kDa, Protein from Homo sapiens)
28s ribosomal protein s34, mitochondrial (25 kDa, Protein from Homo sapiens)
28s ribosomal protein s27, mitochondrial (47 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Homo sapiens)
39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Homo sapiens)
28s ribosomal protein s7, mitochondrial (28 kDa, Protein from Homo sapiens)
12s mitochondrial rrna (306 kDa, RNA from Homo sapiens)
39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Homo sapiens)
28s ribosomal protein s10, mitochondrial (23 kDa, Protein from Homo sapiens)
28s ribosomal protein s35, mitochondrial (36 kDa, Protein from Homo sapiens)
28s ribosomal protein s33, mitochondrial (12 kDa, Protein from Homo sapiens)
39s ribosomal protein l36, mitochondrial (11 kDa, Protein from Homo sapiens)
39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Homo sapiens)
39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Homo sapiens)
Aurora kinase a-interacting protein (22 kDa, Protein from Homo sapiens)
39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Homo sapiens)
39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Homo sapiens)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)

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EMD-16897

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55S human mitochondrial ribosome with mtRF1 and P-site tRNA

Release date: June 14, 2023
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8oir
Q-score: 0.434

Saurer M, Leibundgut M, Nadimpalli HP, Scaiola A, Schonhut T, Lee RG, Siira SJ, Rackham O, Dreos R, Lenarcic T, Kummer E, Gatfield D, Filipovska A, Ban N

Science (2023) 380 pp. 531-536 [ Pubmed: 37141370 DOI: doi:10.1126/science.adf9890 ]

Sample:

28s ribosomal protein s26, mitochondrial (24 kDa, Protein from Homo sapiens)
39s ribosomal protein l12, mitochondrial (21 kDa, Protein from Homo sapiens)
39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Homo sapiens)
28s ribosomal protein s11, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Homo sapiens)
28s ribosomal protein s12, mitochondrial (15 kDa, Protein from Homo sapiens)
Fe-s-o hybrid cluster (335 Da, Ligand)
28s ribosomal protein s24, mitochondrial (19 kDa, Protein from Homo sapiens)
28s ribosomal protein s29, mitochondrial (45 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
39s ribosomal protein l1, mitochondrial (36 kDa, Protein from Homo sapiens)
39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Homo sapiens)
39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Homo sapiens)
P-site met-trna(met) (22 kDa, RNA from Homo sapiens)
Valine (117 Da, Ligand)
39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Homo sapiens)
39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Homo sapiens)
39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Homo sapiens)
Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Homo sapiens)
28s ribosomal protein s16, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s14, mitochondrial (15 kDa, Protein from Homo sapiens)
Potassium ion (39 Da, Ligand)
39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Homo sapiens)
28s ribosomal protein s2, mitochondrial (33 kDa, Protein from Homo sapiens)
39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Homo sapiens)
Ribosomal protein 63, mitochondrial (12 kDa, Protein from Homo sapiens)
Guanosine-5'-diphosphate (443 Da, Ligand)
28s ribosomal protein s6, mitochondrial (14 kDa, Protein from Homo sapiens)
Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Homo sapiens)
39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Homo sapiens)
39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Homo sapiens)
12s rrna (306 kDa, RNA from Homo sapiens)
39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Homo sapiens)
28s ribosomal protein s18c, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s31, mitochondrial (45 kDa, Protein from Homo sapiens)
39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Homo sapiens)
Water (18 Da, Ligand)
39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Homo sapiens)
39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Homo sapiens)
28s ribosomal protein s17, mitochondrial (14 kDa, Protein from Homo sapiens)
39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Homo sapiens)
39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Homo sapiens)
28s ribosomal protein s15, mitochondrial (29 kDa, Protein from Homo sapiens)
39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Homo sapiens)
39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Homo sapiens)
39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Homo sapiens)
39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Homo sapiens)
28s ribosomal protein s34, mitochondrial (25 kDa, Protein from Homo sapiens)
28s ribosomal protein s9, mitochondrial (45 kDa, Protein from Homo sapiens)
39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Homo sapiens)
Mrna (7 kDa, RNA from Homo sapiens)
39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Methionine (149 Da, Ligand)
39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Homo sapiens)
39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Homo sapiens)
28s ribosomal protein s28, mitochondrial (20 kDa, Protein from Homo sapiens)
16s rrna (500 kDa, RNA from Homo sapiens)
39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Homo sapiens)
28s ribosomal protein s22, mitochondrial (41 kDa, Protein from Homo sapiens)
Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 (13 kDa, Protein from Homo sapiens)
39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Homo sapiens)
39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Homo sapiens)
39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Homo sapiens)
Pentatricopeptide repeat domain-containing protein 3, mitochondrial (78 kDa, Protein from Homo sapiens)
39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Homo sapiens)
E-site trna (894 Da, RNA from Homo sapiens)
Peptide chain release factor 1, mitochondrial (56 kDa, Protein from Homo sapiens)
55s human mitochondrial ribosome with mtrf1 and p-site trna (50 kDa, Complex from Homo sapiens)
39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Homo sapiens)
28s ribosomal protein s25, mitochondrial (20 kDa, Protein from Homo sapiens)
Cp val-trna(val) (22 kDa, RNA from Homo sapiens)
39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Homo sapiens)
28s ribosomal protein s5, mitochondrial (48 kDa, Protein from Homo sapiens)
39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s18b, mitochondrial (29 kDa, Protein from Homo sapiens)
28s ribosomal protein s23, mitochondrial (21 kDa, Protein from Homo sapiens)
28s ribosomal protein s21, mitochondrial (10 kDa, Protein from Homo sapiens)
28s ribosomal protein s27, mitochondrial (47 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Homo sapiens)
39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Homo sapiens)
28s ribosomal protein s7, mitochondrial (28 kDa, Protein from Homo sapiens)
39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Homo sapiens)
28s ribosomal protein s10, mitochondrial (23 kDa, Protein from Homo sapiens)
28s ribosomal protein s35, mitochondrial (36 kDa, Protein from Homo sapiens)
28s ribosomal protein s33, mitochondrial (12 kDa, Protein from Homo sapiens)
39s ribosomal protein l36, mitochondrial (11 kDa, Protein from Homo sapiens)
39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Homo sapiens)
39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Homo sapiens)
Aurora kinase a-interacting protein (22 kDa, Protein from Homo sapiens)
39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Homo sapiens)
39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Homo sapiens)

[Show more]

EMD-16898

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28S human mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA

Release date: June 14, 2023
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8ois
Q-score: 0.454

Saurer M, Leibundgut M, Nadimpalli HP, Scaiola A, Schonhut T, Lee RG, Siira SJ, Rackham O, Dreos R, Lenarcic T, Kummer E, Gatfield D, Filipovska A, Ban N

Science (2023) 380 pp. 531-536 [ Pubmed: 37141370 DOI: doi:10.1126/science.adf9890 ]

Sample:

28s ribosomal protein s18b, mitochondrial (29 kDa, Protein from Homo sapiens)
28s ribosomal protein s26, mitochondrial (24 kDa, Protein from Homo sapiens)
28s ribosomal protein s23, mitochondrial (21 kDa, Protein from Homo sapiens)
28s ribosomal protein s21, mitochondrial (10 kDa, Protein from Homo sapiens)
28s ribosomal protein s11, mitochondrial (20 kDa, Protein from Homo sapiens)
28s ribosomal protein s12, mitochondrial (15 kDa, Protein from Homo sapiens)
Fe-s-o hybrid cluster (335 Da, Ligand)
28s ribosomal protein s24, mitochondrial (19 kDa, Protein from Homo sapiens)
28s ribosomal protein s29, mitochondrial (45 kDa, Protein from Homo sapiens)
28s ribosomal protein s17, mitochondrial (14 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
28s ribosomal protein s27, mitochondrial (47 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
P-site met-trna(met) (22 kDa, RNA from Homo sapiens)
28s ribosomal protein s28, mitochondrial (20 kDa, Protein from Homo sapiens)
28s ribosomal protein s22, mitochondrial (41 kDa, Protein from Homo sapiens)
28s ribosomal protein s15, mitochondrial (29 kDa, Protein from Homo sapiens)
39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s7, mitochondrial (28 kDa, Protein from Homo sapiens)
Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 (13 kDa, Protein from Homo sapiens)
Peptide chain release factor 1, mitochondrial,mtrf1(aaq) (56 kDa, Protein from Homo sapiens)
28s ribosomal protein s16, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s14, mitochondrial (15 kDa, Protein from Homo sapiens)
Potassium ion (39 Da, Ligand)
Magnesium ion (24 Da, Ligand)
Pentatricopeptide repeat domain-containing protein 3, mitochondrial (78 kDa, Protein from Homo sapiens)
28s ribosomal protein s10, mitochondrial (23 kDa, Protein from Homo sapiens)
28s human mitochondrial small ribosomal subunit with mtrf1, mrna, and p-site trna (50 kDa, Complex from Homo sapiens)
28s ribosomal protein s2, mitochondrial (33 kDa, Protein from Homo sapiens)
28s ribosomal protein s35, mitochondrial (36 kDa, Protein from Homo sapiens)
28s ribosomal protein s33, mitochondrial (12 kDa, Protein from Homo sapiens)
Guanosine-5'-diphosphate (443 Da, Ligand)
28s ribosomal protein s6, mitochondrial (14 kDa, Protein from Homo sapiens)
28s ribosomal protein s25, mitochondrial (20 kDa, Protein from Homo sapiens)
28s ribosomal protein s31, mitochondrial (45 kDa, Protein from Homo sapiens)
28s ribosomal protein s34, mitochondrial (25 kDa, Protein from Homo sapiens)
28s ribosomal protein s9, mitochondrial (45 kDa, Protein from Homo sapiens)
39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Homo sapiens)
Water (18 Da, Ligand)
12s rrna (306 kDa, RNA from Homo sapiens)
Aurora kinase a-interacting protein (22 kDa, Protein from Homo sapiens)
Mrna (7 kDa, RNA from Homo sapiens)
28s ribosomal protein s18c, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s5, mitochondrial (48 kDa, Protein from Homo sapiens)
Methionine (149 Da, Ligand)

[Show more]

EMD-13982

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Human mitochondrial ribosome in complex with mRNA, A/P- and P/E-tRNAs at 2.98 A resolution

Release date: May 17, 2023
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 7qi6
Q-score: 0.539

Singh V, Itoh Y, Del'Olio S, Hassan A, Naschberger A, Flygaard RK, Nobe Y, Izumikawa K, Aibara S, Andrell J, Whitford PC, Barrientos A, Taoka M, Amunts A

bioRxiv (2023) [ Pubmed: 37503168 DOI: doi:10.1101/2023.05.24.542018 ]

Sample:

28s ribosomal protein s26, mitochondrial (24 kDa, Protein from Homo sapiens)
39s ribosomal protein l12, mitochondrial (21 kDa, Protein from Homo sapiens)
39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Homo sapiens)
28s ribosomal protein s11, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Homo sapiens)
28s ribosomal protein s12, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s24, mitochondrial (19 kDa, Protein from Homo sapiens)
28s ribosomal protein s29, mitochondrial (45 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
39s ribosomal protein l1, mitochondrial (36 kDa, Protein from Homo sapiens)
16s mitochondrial rrna (500 kDa, RNA from Homo sapiens)
39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Homo sapiens)
39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Homo sapiens)
Valine (117 Da, Ligand)
39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Homo sapiens)
39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Homo sapiens)
Spermine (202 Da, Ligand)
39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Homo sapiens)
Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Homo sapiens)
28s ribosomal protein s16, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s14, mitochondrial (15 kDa, Protein from Homo sapiens)
Potassium ion (39 Da, Ligand)
28s ribosomal protein s2, mitochondrial (33 kDa, Protein from Homo sapiens)
39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Homo sapiens)
39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Homo sapiens)
Ribosomal protein 63, mitochondrial (12 kDa, Protein from Homo sapiens)
Guanosine-5'-diphosphate (443 Da, Ligand)
28s ribosomal protein s6, mitochondrial (14 kDa, Protein from Homo sapiens)
Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Homo sapiens)
39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Homo sapiens)
39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Homo sapiens)
39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Homo sapiens)
28s ribosomal protein s31, mitochondrial (45 kDa, Protein from Homo sapiens)
28s ribosomal protein s18c, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Homo sapiens)
Water (18 Da, Ligand)
39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Homo sapiens)
28s ribosomal protein s17, mitochondrial (14 kDa, Protein from Homo sapiens)
39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Homo sapiens)
39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Homo sapiens)
Spermidine (145 Da, Ligand)
39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Homo sapiens)
28s ribosomal protein s15, mitochondrial (29 kDa, Protein from Homo sapiens)
39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Homo sapiens)
1,4-diaminobutane (88 Da, Ligand)
39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Homo sapiens)
39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Homo sapiens)
39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Homo sapiens)
39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Homo sapiens)
Human mitochondrial ribosome (Complex from Homo sapiens)
Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
P/e-trna (22 kDa, RNA from Homo sapiens)
A/p-trna (21 kDa, RNA from Homo sapiens)
Mitochondrial trnaval (22 kDa, RNA from Homo sapiens)
28s ribosomal protein s9, mitochondrial (45 kDa, Protein from Homo sapiens)
39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Homo sapiens)
39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Homo sapiens)
28s ribosomal protein s28, mitochondrial (20 kDa, Protein from Homo sapiens)
28s ribosomal protein s22, mitochondrial (41 kDa, Protein from Homo sapiens)
39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Homo sapiens)
Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 (13 kDa, Protein from Homo sapiens)
Mrps21 isoform 1 (10 kDa, Protein from Homo sapiens)
39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Homo sapiens)
39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Homo sapiens)
Pentatricopeptide repeat domain-containing protein 3, mitochondrial (78 kDa, Protein from Homo sapiens)
39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Homo sapiens)
39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Homo sapiens)
28s ribosomal protein s25, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Homo sapiens)
39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Homo sapiens)
39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Homo sapiens)
28s ribosomal protein s5, mitochondrial (48 kDa, Protein from Homo sapiens)
28s ribosomal protein s18b, mitochondrial (29 kDa, Protein from Homo sapiens)
39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s23, mitochondrial (21 kDa, Protein from Homo sapiens)
28s ribosomal protein s34, mitochondrial (25 kDa, Protein from Homo sapiens)
28s ribosomal protein s27, mitochondrial (47 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Homo sapiens)
39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Homo sapiens)
28s ribosomal protein s7, mitochondrial (28 kDa, Protein from Homo sapiens)
12s mitochondrial rrna (306 kDa, RNA from Homo sapiens)
Mrna (10 kDa, RNA from Homo sapiens)
39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Homo sapiens)
28s ribosomal protein s10, mitochondrial (23 kDa, Protein from Homo sapiens)
28s ribosomal protein s35, mitochondrial (36 kDa, Protein from Homo sapiens)
28s ribosomal protein s33, mitochondrial (12 kDa, Protein from Homo sapiens)
39s ribosomal protein l36, mitochondrial (11 kDa, Protein from Homo sapiens)
39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Homo sapiens)
39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Homo sapiens)
Aurora kinase a-interacting protein (22 kDa, Protein from Homo sapiens)
39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Homo sapiens)
39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Homo sapiens)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)

[Show more]

EMD-26966

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Human mitochondrial small subunit assembly intermediate (State A)

Release date: Dec. 14, 2022
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8csp
Q-score: 0.548

Harper NJ, Burnside C, Klinge S

Nature (2023) 614 pp. 175-181 [ Pubmed: 36482135 DOI: doi:10.1038/s41586-022-05621-0 ]

Sample:

28s ribosomal protein s35, mitochondrial (36 kDa, Protein from Homo sapiens)
28s ribosomal protein s28, mitochondrial (20 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
28s ribosomal protein s2, mitochondrial (33 kDa, Protein from Homo sapiens)
28s ribosomal protein s29, mitochondrial (45 kDa, Protein from Homo sapiens)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
28s ribosomal protein s17, mitochondrial (14 kDa, Protein from Homo sapiens)
28s ribosomal protein s31, mitochondrial (45 kDa, Protein from Homo sapiens)
28s ribosomal protein s23, mitochondrial (21 kDa, Protein from Homo sapiens)
28s ribosomal protein s26, mitochondrial (24 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
28s ribosomal protein s24, mitochondrial (19 kDa, Protein from Homo sapiens)
28s ribosomal protein s5, mitochondrial (48 kDa, Protein from Homo sapiens)
28s ribosomal protein s21, mitochondrial (10 kDa, Protein from Homo sapiens)
28s ribosomal protein s10, mitochondrial (23 kDa, Protein from Homo sapiens)
Dimethyladenosine transferase 1, mitochondrial (39 kDa, Protein from Homo sapiens)
28s ribosomal protein s27, mitochondrial (47 kDa, Protein from Homo sapiens)
Pentatricopeptide repeat domain-containing protein 3, mitochondrial (78 kDa, Protein from Homo sapiens)
Iron/sulfur cluster (351 Da, Ligand)
Gtpase era, mitochondrial (48 kDa, Protein from Homo sapiens)
28s ribosomal protein s16, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s18c, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s34, mitochondrial (25 kDa, Protein from Homo sapiens)
28s ribosomal protein s9, mitochondrial (45 kDa, Protein from Homo sapiens)
Potassium ion (39 Da, Ligand)
28s ribosomal protein s12, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s6, mitochondrial (14 kDa, Protein from Homo sapiens)
Nitric oxide-associated protein 1 (78 kDa, Protein from Homo sapiens)
12s mitochondrial rrna (306 kDa, RNA from Homo sapiens)
28s ribosomal protein s18b, mitochondrial (29 kDa, Protein from Homo sapiens)
Malonyl-coa-acyl carrier protein transacylase, mitochondrial (43 kDa, Protein from Homo sapiens)
Methyltransferase-like protein 17, mitochondrial (50 kDa, Protein from Homo sapiens)
28s ribosomal protein s33, mitochondrial (12 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
Guanosine-5'-diphosphate (443 Da, Ligand)
28s ribosomal protein s7, mitochondrial (28 kDa, Protein from Homo sapiens)
28s ribosomal protein s15, mitochondrial (29 kDa, Protein from Homo sapiens)
28s ribosomal protein s14, mitochondrial (15 kDa, Protein from Homo sapiens)
S-adenosylmethionine (398 Da, Ligand)
Human mitochondrial small subunit assembly intermediate, state a (1 MDa, Complex from Homo sapiens)
28s ribosomal protein s22, mitochondrial (41 kDa, Protein from Homo sapiens)
28s ribosomal protein s25, mitochondrial (20 kDa, Protein from Homo sapiens)

[Show more]

EMD-26967

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Human mitochondrial small subunit assembly intermediate (State B)

Release date: Dec. 14, 2022
Resolution: 2.54 Å
EM Method: Single-particle
Fitted PDBs: 8csq
Q-score: 0.566

Harper NJ, Burnside C, Klinge S

Nature (2023) 614 pp. 175-181 [ Pubmed: 36482135 DOI: doi:10.1038/s41586-022-05621-0 ]

Sample:

28s ribosomal protein s35, mitochondrial (36 kDa, Protein from Homo sapiens)
28s ribosomal protein s28, mitochondrial (20 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
28s ribosomal protein s2, mitochondrial (33 kDa, Protein from Homo sapiens)
28s ribosomal protein s29, mitochondrial (45 kDa, Protein from Homo sapiens)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)
28s ribosomal protein s17, mitochondrial (14 kDa, Protein from Homo sapiens)
28s ribosomal protein s31, mitochondrial (45 kDa, Protein from Homo sapiens)
28s ribosomal protein s23, mitochondrial (21 kDa, Protein from Homo sapiens)
28s ribosomal protein s26, mitochondrial (24 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
28s ribosomal protein s24, mitochondrial (19 kDa, Protein from Homo sapiens)
28s ribosomal protein s5, mitochondrial (48 kDa, Protein from Homo sapiens)
28s ribosomal protein s21, mitochondrial (10 kDa, Protein from Homo sapiens)
28s ribosomal protein s10, mitochondrial (23 kDa, Protein from Homo sapiens)
Dimethyladenosine transferase 1, mitochondrial (39 kDa, Protein from Homo sapiens)
28s ribosomal protein s27, mitochondrial (47 kDa, Protein from Homo sapiens)
Pentatricopeptide repeat domain-containing protein 3, mitochondrial (78 kDa, Protein from Homo sapiens)
Iron/sulfur cluster (351 Da, Ligand)
Gtpase era, mitochondrial (48 kDa, Protein from Homo sapiens)
28s ribosomal protein s16, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s18c, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s34, mitochondrial (25 kDa, Protein from Homo sapiens)
28s ribosomal protein s9, mitochondrial (45 kDa, Protein from Homo sapiens)
Potassium ion (39 Da, Ligand)
28s ribosomal protein s12, mitochondrial (15 kDa, Protein from Homo sapiens)
28s ribosomal protein s6, mitochondrial (14 kDa, Protein from Homo sapiens)
12s mitochondrial rrna (306 kDa, RNA from Homo sapiens)
28s ribosomal protein s18b, mitochondrial (29 kDa, Protein from Homo sapiens)
Malonyl-coa-acyl carrier protein transacylase, mitochondrial (43 kDa, Protein from Homo sapiens)
Methyltransferase-like protein 17, mitochondrial (50 kDa, Protein from Homo sapiens)
Aurora kinase a-interacting protein (22 kDa, Protein from Homo sapiens)
28s ribosomal protein s33, mitochondrial (12 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
Guanosine-5'-diphosphate (443 Da, Ligand)
28s ribosomal protein s7, mitochondrial (28 kDa, Protein from Homo sapiens)
28s ribosomal protein s15, mitochondrial (29 kDa, Protein from Homo sapiens)
28s ribosomal protein s14, mitochondrial (15 kDa, Protein from Homo sapiens)
S-adenosylmethionine (398 Da, Ligand)
28s ribosomal protein s22, mitochondrial (41 kDa, Protein from Homo sapiens)
Human mitochondrial small subunit assembly intermediate, state b (1 MDa, Complex from Homo sapiens)
28s ribosomal protein s25, mitochondrial (20 kDa, Protein from Homo sapiens)

[Show more]

EMD-26968

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Human mitochondrial small subunit assembly intermediate (State C)

Release date: Dec. 14, 2022
Resolution: 2.54 Å
EM Method: Single-particle
Fitted PDBs: 8csr
Q-score: 0.563

Harper NJ, Burnside C, Klinge S

Nature (2023) 614 pp. 175-181 [ Pubmed: 36482135 DOI: doi:10.1038/s41586-022-05621-0 ]

Sample:

Aurora kinase a-interacting protein (22 kDa, Protein from human)
28s ribosomal protein s5, mitochondrial (48 kDa, Protein from human)
Putative ribosome-binding factor a, mitochondrial (38 kDa, Protein from human)
Dimethyladenosine transferase 1, mitochondrial (39 kDa, Protein from human)
28s ribosomal protein s27, mitochondrial (47 kDa, Protein from human)
28s ribosomal protein s2, mitochondrial (33 kDa, Protein from human)
28s ribosomal protein s33, mitochondrial (12 kDa, Protein from human)
28s ribosomal protein s23, mitochondrial (21 kDa, Protein from human)
Adenosine-5'-triphosphate (507 Da, Ligand)
28s ribosomal protein s34, mitochondrial (25 kDa, Protein from human)
Zinc ion (65 Da, Ligand)
S-adenosylmethionine (398 Da, Ligand)
28s ribosomal protein s10, mitochondrial (23 kDa, Protein from human)
28s ribosomal protein s12, mitochondrial (15 kDa, Protein from human)
Pentatricopeptide repeat domain-containing protein 3, mitochondrial (78 kDa, Protein from human)
28s ribosomal protein s16, mitochondrial (15 kDa, Protein from human)
28s ribosomal protein s26, mitochondrial (24 kDa, Protein from human)
28s ribosomal protein s21, mitochondrial (10 kDa, Protein from human)
28s ribosomal protein s18c, mitochondrial (15 kDa, Protein from human)
28s ribosomal protein s31, mitochondrial (45 kDa, Protein from human)
28s ribosomal protein s7, mitochondrial (28 kDa, Protein from human)
28s ribosomal protein s18b, mitochondrial (29 kDa, Protein from human)
Malonyl-coa-acyl carrier protein transacylase, mitochondrial (43 kDa, Protein from human)
Human mitochondrial small subunit assembly intermediate, state c (1 MDa, Complex from Homo sapiens)
Potassium ion (39 Da, Ligand)
Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
Iron/sulfur cluster (351 Da, Ligand)
28s ribosomal protein s14, mitochondrial (15 kDa, Protein from human)
28s ribosomal protein s29, mitochondrial (45 kDa, Protein from human)
Guanosine-5'-diphosphate (443 Da, Ligand)
28s ribosomal protein s15, mitochondrial (29 kDa, Protein from human)
28s ribosomal protein s35, mitochondrial (36 kDa, Protein from human)
28s ribosomal protein s25, mitochondrial (20 kDa, Protein from human)
28s ribosomal protein s22, mitochondrial (41 kDa, Protein from human)
Methyltransferase-like protein 17, mitochondrial (50 kDa, Protein from human)
28s ribosomal protein s28, mitochondrial (20 kDa, Protein from human)
12s mitochondrial rrna (306 kDa, RNA from human)
28s ribosomal protein s9, mitochondrial (45 kDa, Protein from human)
Water (18 Da, Ligand)
28s ribosomal protein s11, mitochondrial (20 kDa, Protein from human)
28s ribosomal protein s24, mitochondrial (19 kDa, Protein from human)
28s ribosomal protein s17, mitochondrial (14 kDa, Protein from human)
28s ribosomal protein s6, mitochondrial (14 kDa, Protein from human)
Magnesium ion (24 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)

[Show more]

EMD-26969

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Human mitochondrial small subunit assembly intermediate (State D)

Release date: Dec. 14, 2022
Resolution: 2.36 Å
EM Method: Single-particle
Fitted PDBs: 8css
Q-score: 0.576

Harper NJ, Burnside C, Klinge S

Nature (2023) 614 pp. 175-181 [ Pubmed: 36482135 DOI: doi:10.1038/s41586-022-05621-0 ]

Sample:

Aurora kinase a-interacting protein (22 kDa, Protein from human)
12s mitochondrial rrna (306 kDa, RNA from human)
28s ribosomal protein s5, mitochondrial (48 kDa, Protein from human)
Putative ribosome-binding factor a, mitochondrial (38 kDa, Protein from human)
28s ribosomal protein s27, mitochondrial (47 kDa, Protein from human)
28s ribosomal protein s2, mitochondrial (33 kDa, Protein from human)
28s ribosomal protein s33, mitochondrial (12 kDa, Protein from human)
28s ribosomal protein s23, mitochondrial (21 kDa, Protein from human)
Adenosine-5'-triphosphate (507 Da, Ligand)
28s ribosomal protein s34, mitochondrial (25 kDa, Protein from human)
Zinc ion (65 Da, Ligand)
S-adenosylmethionine (398 Da, Ligand)
28s ribosomal protein s10, mitochondrial (23 kDa, Protein from human)
28s ribosomal protein s12, mitochondrial (15 kDa, Protein from human)
Pentatricopeptide repeat domain-containing protein 3, mitochondrial (78 kDa, Protein from human)
28s ribosomal protein s16, mitochondrial (15 kDa, Protein from human)
28s ribosomal protein s26, mitochondrial (24 kDa, Protein from human)
28s ribosomal protein s21, mitochondrial (10 kDa, Protein from human)
Human mitochondrial small subunit assembly intermediate, state d (1 MDa, Complex from Homo sapiens)
28s ribosomal protein s18c, mitochondrial (15 kDa, Protein from human)
28s ribosomal protein s31, mitochondrial (45 kDa, Protein from human)
28s ribosomal protein s7, mitochondrial (28 kDa, Protein from human)
28s ribosomal protein s18b, mitochondrial (29 kDa, Protein from human)
Malonyl-coa-acyl carrier protein transacylase, mitochondrial (43 kDa, Protein from human)
Potassium ion (39 Da, Ligand)
Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
Iron/sulfur cluster (351 Da, Ligand)
28s ribosomal protein s14, mitochondrial (15 kDa, Protein from human)
28s ribosomal protein s29, mitochondrial (45 kDa, Protein from human)
Guanosine-5'-diphosphate (443 Da, Ligand)
28s ribosomal protein s15, mitochondrial (29 kDa, Protein from human)
28s ribosomal protein s35, mitochondrial (36 kDa, Protein from human)
28s ribosomal protein s25, mitochondrial (20 kDa, Protein from human)
28s ribosomal protein s22, mitochondrial (41 kDa, Protein from human)
Methyltransferase-like protein 17, mitochondrial (50 kDa, Protein from human)
28s ribosomal protein s28, mitochondrial (20 kDa, Protein from human)
28s ribosomal protein s9, mitochondrial (45 kDa, Protein from human)
Water (18 Da, Ligand)
28s ribosomal protein s11, mitochondrial (20 kDa, Protein from human)
28s ribosomal protein s24, mitochondrial (19 kDa, Protein from human)
28s ribosomal protein s17, mitochondrial (14 kDa, Protein from human)
28s ribosomal protein s6, mitochondrial (14 kDa, Protein from human)
Magnesium ion (24 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)

[Show more]

EMD-26970

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Human mitochondrial small subunit assembly intermediate (State E)

Release date: Dec. 14, 2022
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8cst
Q-score: 0.555

Harper NJ, Burnside C, Klinge S

Nature (2023) 614 pp. 175-181 [ Pubmed: 36482135 DOI: doi:10.1038/s41586-022-05621-0 ]

Sample:

Aurora kinase a-interacting protein (22 kDa, Protein from human)
12s mitochondrial rrna (306 kDa, RNA from human)
28s ribosomal protein s5, mitochondrial (48 kDa, Protein from human)
Putative ribosome-binding factor a, mitochondrial (38 kDa, Protein from human)
28s ribosomal protein s27, mitochondrial (47 kDa, Protein from human)
28s ribosomal protein s2, mitochondrial (33 kDa, Protein from human)
28s ribosomal protein s33, mitochondrial (12 kDa, Protein from human)
28s ribosomal protein s23, mitochondrial (21 kDa, Protein from human)
Adenosine-5'-triphosphate (507 Da, Ligand)
28s ribosomal protein s34, mitochondrial (25 kDa, Protein from human)
Zinc ion (65 Da, Ligand)
S-adenosylmethionine (398 Da, Ligand)
28s ribosomal protein s10, mitochondrial (23 kDa, Protein from human)
28s ribosomal protein s12, mitochondrial (15 kDa, Protein from human)
Pentatricopeptide repeat domain-containing protein 3, mitochondrial (78 kDa, Protein from human)
28s ribosomal protein s16, mitochondrial (15 kDa, Protein from human)
28s ribosomal protein s26, mitochondrial (24 kDa, Protein from human)
Human mitochondrial small subunit assembly intermediate, state e (1 MDa, Complex from Homo sapiens)
28s ribosomal protein s21, mitochondrial (10 kDa, Protein from human)
28s ribosomal protein s18c, mitochondrial (15 kDa, Protein from human)
28s ribosomal protein s31, mitochondrial (45 kDa, Protein from human)
28s ribosomal protein s7, mitochondrial (28 kDa, Protein from human)
28s ribosomal protein s18b, mitochondrial (29 kDa, Protein from human)
Potassium ion (39 Da, Ligand)
Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
Iron/sulfur cluster (351 Da, Ligand)
28s ribosomal protein s14, mitochondrial (15 kDa, Protein from human)
28s ribosomal protein s29, mitochondrial (45 kDa, Protein from human)
Guanosine-5'-diphosphate (443 Da, Ligand)
28s ribosomal protein s15, mitochondrial (29 kDa, Protein from human)
28s ribosomal protein s35, mitochondrial (36 kDa, Protein from human)
28s ribosomal protein s25, mitochondrial (20 kDa, Protein from human)
28s ribosomal protein s22, mitochondrial (41 kDa, Protein from human)
Methyltransferase-like protein 17, mitochondrial (50 kDa, Protein from human)
28s ribosomal protein s28, mitochondrial (20 kDa, Protein from human)
28s ribosomal protein s9, mitochondrial (45 kDa, Protein from human)
28s ribosomal protein s11, mitochondrial (20 kDa, Protein from human)
28s ribosomal protein s24, mitochondrial (19 kDa, Protein from human)
28s ribosomal protein s17, mitochondrial (14 kDa, Protein from human)
28s ribosomal protein s6, mitochondrial (14 kDa, Protein from human)
Magnesium ion (24 Da, Ligand)
Fe2/s2 (inorganic) cluster (175 Da, Ligand)

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